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| ===''Eschericia coli'' (''E. coli'') overview=== | | ===''Eschericia coli'' (''E. coli'') overview=== |
− | | + | [[File:Ecoli.jpg|200px|right]] |
| *Member of ''Enterobacteriacae'' family of Gram-negative bacilli | | *Member of ''Enterobacteriacae'' family of Gram-negative bacilli |
| *'''Facultative anaerobe''' | | *'''Facultative anaerobe''' |
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| *Capsular polysaccharides produced by some strains prevent phagocytosis and interfere with complement | | *Capsular polysaccharides produced by some strains prevent phagocytosis and interfere with complement |
| *Endotoxin is a lipolysaccharide component of the cell wall of Gram-negative bacteria, composed of lipid A, a core polysaccharide and various side chains | | *Endotoxin is a lipolysaccharide component of the cell wall of Gram-negative bacteria, composed of lipid A, a core polysaccharide and various side chains |
− | *'''Endotoxin''' is realeased when bacteria die, and causes endothelial damage leading to [[Disseminated Intravascular Coagulation|'''disseminated intravascular coagulation''']] and e'''ndotoxic shock'''; it is also a '''pyrogen''' | + | *'''Endotoxin''' is realeased when bacteria die, and causes endothelial damage leading to [[Disseminated Intravascular Coagulation|'''disseminated intravascular coagulation''']] and '''endotoxic shock'''; it is also a '''pyrogen''' |
| *Enterotoxins, verotoxins and cytotoxic necrotising factors produced by many pathogenic ''E. coli''; these produce cell damage at their site of action | | *Enterotoxins, verotoxins and cytotoxic necrotising factors produced by many pathogenic ''E. coli''; these produce cell damage at their site of action |
| *'''Alpha-haemolysin''' may increase iron availability for invading organisms | | *'''Alpha-haemolysin''' may increase iron availability for invading organisms |
| *'''Siderophores''' are made by certain pathogenic strains, and are responsible for iron aquisition; they include aerobactin and enterobactin | | *'''Siderophores''' are made by certain pathogenic strains, and are responsible for iron aquisition; they include aerobactin and enterobactin |
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| ==Extra-intestinal infection== | | ==Extra-intestinal infection== |
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| ***Most common organism infecting urinary tract | | ***Most common organism infecting urinary tract |
| ***Ascending infections of urinary tract | | ***Ascending infections of urinary tract |
− | ***Causes pyometra in the dog and cat and [[Kidney Tubulointerstitial Disease - Pathology#Pyelonephritis|pyelonephritis]] | + | ***Causes pyometra in the dog and cat and [[Pyelonephritis|pyelonephritis]] |
| ***Cystitis in the bitch | | ***Cystitis in the bitch |
| ***Prostatitis in dogs via opportunistic infection | | ***Prostatitis in dogs via opportunistic infection |