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==Introduction==
 
==Introduction==
Porcine reproductive and respiratory syndrome (PRRS) first appeared in the USA in 1987, although subsequent serologic evidence indicated that it had been circulating for some time prior to being recognised. The disease was seen in Europe in 1990 and reported in Humberside in the UK in 1991. PRRS is caused by an arterivirus, and leads to abortions, mortality and reduced growth, significantly impacting pig welfare and production economics worldwide.
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Porcine reproductive and respiratory syndrome (PRRS) first appeared in the USA in 1987, although subsequent serologic evidence indicated that it had been circulating for some time prior to being recognised. The disease was seen in Europe in 1990 and reported in Humberside in the UK in 1991. PRRS is caused by an arterivirus, and leads to abortions, mortality and reduced growth, significantly impacting pig welfare and production economics worldwide. This disease is now found in most areas of the world where pigs are raised. Besides Europe and North America, it was identified in China in 1995 and is present in Japan, Vietnam, the Philippines, Malaysia, and Korea among other countries in Asia. Australia, New Zealand, several European countries are currently free of the disease.
    
==Aetiology==
 
==Aetiology==
The virus that causes PRRS is an aterivirus, within the [[:Category:Arteriviridae|Arteriviridae]] family. The arteriviruses are the only genus contained within the Arterivirdae family, and other members include the agent responsible for [[Equine Viral Arteritis|equine viral arteritis]] and lactate dehydrogenase-elevating virus of mice. The viruses are host-specific and antigenically distinct, and establish persistent infections after invasion.  
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The virus that causes PRRS is an arterivirus, within the [[:Category:Arteriviridae|Arteriviridae]] family. The arteriviruses are the only genus contained within the Arterivirdae family, and other members include the agent responsible for [[Equine Viral Arteritis|equine viral arteritis]] and lactate dehydrogenase-elevating virus of mice. The viruses are host-specific and antigenically distinct, and establish persistent infections after invasion.
    
==Transmission and Epidemiology==
 
==Transmission and Epidemiology==
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Both modified live and killed vaccines are available. These are effective in controlling outbreaks and preventing economic losses.
 
Both modified live and killed vaccines are available. These are effective in controlling outbreaks and preventing economic losses.
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==Literature Search==
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{{Learning
[[File:CABI logo.jpg|left|90px]]
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|powerpoints = [[E-Lecture:Porcine Reproductive and Respiratory Syndrome]]
 
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|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Porcine+Reproductive+and+Respiratory+Syndrome&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=2000&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=41&y=7 Porcine Reproductive and Respiratory Syndrome publications since 2000]
 
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|full text = [http://www.cabi.org/cabdirect/FullTextPDF/2006/20063124592.pdf ''' What's new with PRRS and SIV from the diagnostic lab.''' Rossow, K.; The North American Veterinary Conference, Gainesville, USA, Large animal. Proceedings of the North American Veterinary Conference, Volume 20, Orlando, Florida, USA, 7-11 January, 2006, 2006, pp 330-331, 1 ref.]
Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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}}
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[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Porcine+Reproductive+and+Respiratory+Syndrome&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&publishedstart=2000&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all&x=41&y=7 Porcine Reproductive and Respiratory Syndrome publications since 2000]
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[http://www.cabi.org/cabdirect/FullTextPDF/2006/20063124592.pdf ''' What's new with PRRS and SIV from the diagnostic lab.''' Rossow, K.; The North American Veterinary Conference, Gainesville, USA, Large animal. Proceedings of the North American Veterinary Conference, Volume 20, Orlando, Florida, USA, 7-11 January, 2006, 2006, pp 330-331, 1 ref. - '''Full Text Article''']
      
==Links==
 
==Links==
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#OIE (2008) [http://www.oie.int/downld/Doc_OIE/PRRS_guide_web_bulletin.pdf PRRS: the disease, its diagnosis, prevention and control.] ''Report of the OIE ad hoc Group on Porcine Reproductive and Respiratory Syndrome''.
 
#OIE (2008) [http://www.oie.int/downld/Doc_OIE/PRRS_guide_web_bulletin.pdf PRRS: the disease, its diagnosis, prevention and control.] ''Report of the OIE ad hoc Group on Porcine Reproductive and Respiratory Syndrome''.
 
#Laegreid, W (2006) Porcine Reproductive and Respiratory Syndrome. ''Proceedings of the Annual Meeting of the American College of Veterinary Pathologists and American Society for Veterinary Clinical Pathology''.
 
#Laegreid, W (2006) Porcine Reproductive and Respiratory Syndrome. ''Proceedings of the Annual Meeting of the American College of Veterinary Pathologists and American Society for Veterinary Clinical Pathology''.
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#OIE (2011) [http://www.oie.int/doc/ged/D13986.PDF Porcine reproductive and respiratory syndrome-General Disease Information Sheets] ''Porcine Reproductive and Respiratory Syndrome''.
     
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