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− | {{toplink
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− | |backcolour = D1EEEE
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− | |linkpage =Cardiorespiratory System - Pathology
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− | |linktext =Cardiorespiratory System
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− | |maplink = Cardiorespiratory System (Content Map) - Pathology
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− | |pagetype =Pathology
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− | |sublink1=Lungs - Pathology
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− | |subtext1=LUNGS
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− | }}
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− | <br>
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| ==Classification== | | ==Classification== |
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| *However, primary tumours are more common in dogs and cats than in other animals | | *However, primary tumours are more common in dogs and cats than in other animals |
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− | *Classification of pulmonary tumours can be difficult due to the [[General Pathology - Disorders of Cell Growth#Metaplasia|metaplasia]] which can occur in both inflammation and in neoplasia | + | *Classification of pulmonary tumours can be difficult due to the [[Cell Growth Disorders#Metaplasia|metaplasia]] which can occur in both inflammation and in neoplasia |
| **Bronchial papilloma | | **Bronchial papilloma |
| **Bronchial adenoma/ carcinoma (arising from major airways) | | **Bronchial adenoma/ carcinoma (arising from major airways) |
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− | ===Sheep pulmonary adenomatosis (SPA/ Jaagsiekte)=== | + | ===[[Sheep Pulmonary Adenomatosis]] (SPA/ Jaagsiekte)=== |
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− | *Also called '''pulmonary carcinomatosis'''
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− | *Infectious [[Bronchi and Bronchioles Inflammatory - Pathology#Infectious causes of bronchitis or bronchiolitis|bronchiolar]]-[[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|alveolar]] carcinoma caused by a [[Retroviridae|retrovirus]]
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− | *Commonest under intensive management systems which favour aerosol transmission and close contact of disease
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− | *Behaves like chronic pneumonia
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− | *Takes months to years to express itself clinically as coughing and exercise intolerance
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− | *Gross pathology:
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− | **Heavy lungs which fail to collapse
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− | **The lesions progress from small firm grey/white nodular lesions to extensive confluent areas with replacement by neoplastic tissue
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− | **Cut surface oozes fluid
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− | **There is often coexistent infection present
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− | **Occasional metastases to bronchial and mediastinal lymph nodes can occur
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− | *Histopathology:
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− | **Widespread proliferation of alveolar (Type 2) and terminal bronchiolar epithelium, lining the alveoli and lower airways
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− | **Multiple neoplastic foci of cuboidal/columnar cells forming papillary projections into the lumen
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− | **Metastases of the same in the bronchial and mediastinal lymph nodes
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− | *There is no serological test, and diagnosis depends upon raising the animal by the hind limbs whereupon a clear fluid issues from the nose = "Wheelbarrow test"
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| ===Carcinoids=== | | ===Carcinoids=== |
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| *Also called '''myoblastomas''' | | *Also called '''myoblastomas''' |
| *Mesenchymal origin | | *Mesenchymal origin |
− | *Occurs in [[Hindgut Fermenters - Horse - Anatomy & Physiology|horses]] | + | *Occurs in [[Alimentary System - Horse Anatomy|horses]] |
| *Grossly: | | *Grossly: |
| **Multiple discrete of partially confluent nodules | | **Multiple discrete of partially confluent nodules |
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| **Mammary carcinoma (dog and cat) | | **Mammary carcinoma (dog and cat) |
| **Haemangiosarcomas | | **Haemangiosarcomas |
− | **[[Bones - hyperplastic and neoplastic#Osteosarcoma (OSA)|Osteosarcomas]] | + | **[[Osteosarcoma|Osteosarcomas]] |
| **Uterine adenocarcinoma (cattle) | | **Uterine adenocarcinoma (cattle) |
| **Malignant melanoma (horse) | | **Malignant melanoma (horse) |
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| *'''In horses''' | | *'''In horses''' |
− | **cranial mediastinal lymphosarcoma | + | **cranial mediastinal [[lymphosarcoma]] |
| **pulmonary granular cell tumour | | **pulmonary granular cell tumour |
| **malignant melanoma | | **malignant melanoma |
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− | <big>A space occupying lesion in the canine lung may produce periosteal thickening of the long bone - [[Bones - hyperplastic and neoplastic#Hypertrophic osteopathy|'''Hypertrophic Osteopathy''']]</big> | + | <big>A space occupying lesion in the canine lung may produce periosteal thickening of the long bone - [[Hypertrophic Osteopathy|'''Hypertrophic Osteopathy''']]</big> |
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| + | ==Test yourself with the Lungs Pathology Flashcards== |
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| + | [[Lungs_Flashcards_-_Pathology|Lungs Pathology Flashcards]] |
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| + | [[Category:Lungs - Pathology]] |
| + | [[Category:Respiratory System - Hyperplastic/Neoplastic Pathology]] |