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| − | {{review}}
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| | | | |
| | ==Drug administration== | | ==Drug administration== |
| | | | |
| − | The parenteral (e.g. intravenous, intramuscular, subcutaneous, intra-articular) | + | The parenteral (''e.g.'' intravenous, intramuscular, subcutaneous, intra-articular) |
| | or oral routes are used most commonly to administer drugs to donkeys. | | or oral routes are used most commonly to administer drugs to donkeys. |
| | The choice of administration route depends on a number of factors, | | The choice of administration route depends on a number of factors, |
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| | drugs by this route, e.g. atropine has systemic effects following ophthalmic | | drugs by this route, e.g. atropine has systemic effects following ophthalmic |
| | administration. | | administration. |
| | + | |
| | + | <center>'''Factors to consider when selecting an administration route.''' |
| | + | |
| | + | |
| | + | {| cellpadding="10" cellspacing="0" border="1" |
| | + | |'''intravenous (i.v.)''' |
| | + | | '''intramuscular (i.m.)/ subcutaneous (s.c.)''' |
| | + | | '''''per os'', oral (p.o.)''' |
| | + | |- |
| | + | |Rapidly produces high drug concentrations in the circulation |
| | + | |I.m. gives better and more consistent absorption than s.c. |
| | + | |Rate and extent of absorption can be highly variable |
| | + | |- |
| | + | |Can titrate to effect(''e.g.'' anaesthetics) |
| | + | |No more than 30ml per injection site |
| | + | |Bioavailability of drugs can be substantially decreased |
| | + | |- |
| | + | |Increased chance of adverse reactions |
| | + | |Donkeys less sensitive to local side effects (irritation, infection) than horses |
| | + | |Absorption can be delayed or biphasic due to adsorption onto feed |
| | + | |- |
| | + | |Bioavailability 100% |
| | + | |. |
| | + | |Usually safe |
| | + | |- |
| | + | |} |
| | + | </center> |
| | + | |
| | | | |
| | ==References== | | ==References== |
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| | |linkpage =Pharmacology - Donkey | | |linkpage =Pharmacology - Donkey |
| | |linktext =Pharmacology - Donkey | | |linktext =Pharmacology - Donkey |
| − | |rspace={{Donkey}}
| |
| | |pagetype=Donkey | | |pagetype=Donkey |
| | }} | | }} |
| | + | {{infotable |
| | + | |Maintitle = [[Sponsors#The Donkey Sanctuary|This page was sponsored and content provided by '''THE DONKEY SANCTUARY''']] |
| | + | |Maintitlebackcolour = B4CDCD |
| | + | }}[[Category:Donkey]] |
| | + | [[Category:Pharmacology_-_Donkey]] |