Adaptive Immunity to Viruses - Revision history

Bara at 16:16, 2 July 2012

2012-07-02T16:16:05Z

Rjfrancisrvc: /* Cell-Mediated */

2012-05-17T09:46:47Z

Cell-Mediated

Bara at 19:12, 16 March 2012

2012-03-16T19:12:51Z

Bara at 18:59, 13 January 2011

2011-01-13T18:59:53Z

Bara at 18:59, 13 January 2011

2011-01-13T18:59:16Z

Suzannah.stacey at 20:07, 21 October 2010

2010-10-21T20:07:10Z

Bara: Text replace - "Category:To Do - Review" to "Category:To Do - AP Review"

2010-10-18T12:14:37Z

Text replace - "Category:To Do - Review" to "Category:To Do - AP Review"

Aimee.e.hicks at 11:32, 6 September 2010

2010-09-06T11:32:37Z

Aimee.e.hicks at 11:32, 6 September 2010

2010-09-06T11:32:07Z

Aimee.e.hicks at 11:29, 6 September 2010

2010-09-06T11:29:49Z

@@ Line 1: / Line 1: @@
 [[Image:virusimmunity.jpg|350px|right]]
 ==Humoral==
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 <br><br>
 {{Jim Bee 2007}}
 [[Category:Adaptive Immune System]]

← Older revision		Revision as of 09:46, 17 May 2012
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	==Cell-Mediated==		==Cell-Mediated==
−	The cell-mediated response to viruses involves [[Lymphocytes#Cytotoxic CD8+\|CD8+ T-cell]] mediated killing of virus infected cells. They are the main cells involved in the immune response to '''intracellular''' virus infection. Viruses are detected by the recognition of [[Major Histocompatability Complexes#MHC I\|MHC I]]-peptide complex and infected cells are killed by apoptosis. Perforin and granzymes activate the caspase cascade and Fas-ligand triggers the Fas-mediated apoptosis pathway. Cytotoxic [[Cytokines\|cytokines]] (especially TNF-α & TNF-β lymphotoxin) act on TNF receptors to induce programmed cell death.	+	The cell-mediated response to viruses involves [[Lymphocytes#Cytotoxic CD8+\|CD8<sup>+</sup> T-cell]] mediated killing of virus infected cells. They are the main cells involved in the immune response to '''intracellular''' virus infection. Viruses are detected by the recognition of [[Major Histocompatability Complexes#MHC I\|MHC I]]-peptide complex and infected cells are killed by apoptosis. Perforin and granzymes activate the caspase cascade and Fas-ligand triggers the Fas-mediated apoptosis pathway. Cytotoxic [[Cytokines\|cytokines]] (especially TNF-α & TNF-β lymphotoxin) act on TNF receptors to induce programmed cell death.

← Older revision		Revision as of 19:12, 16 March 2012
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−		+	<br><br>
		+	{{Jim Bee 2007}}
	[[Category:Adaptive Immune System]]		[[Category:Adaptive Immune System]]

@@ Line 1: / Line 1: @@
-[[Image:virusimmunity.jpg|thumb|350px|right|'''''']]
+[[Image:virusimmunity.jpg|350px|right]]
 ==Humoral==
 The humoral response to viruses involves the production of '''neutralising antibody''' and '''Antibody-dependent cell mediated cytotoxicity (ADCC)'''. [[Immunoglobulins|Antibody]]-labelled cells can be targeted by [[Lymphocytes#Natural Killer (NK) cells|NK Cells]] as another defence against viral infection. The antibody produced against viral protein can attach to infected cells during their budding phase, which effectively labels them for [[Lymphocytes#Natural Killer (NK) cells|NK]] targeting. [[Lymphocytes#Natural Killer (NK) cells|NK]] cells express Fc&gamma; receptors with which to detect such cells. Once activated, they release a host of enzymes to induce apoptosis of the budding cell.

@@ Line 1: / Line 1: @@
 [[Image:virusimmunity.jpg|thumb|350px|right|'''''']]
 ==Humoral==
-The humoral response to viruses involves the production of '''neutralising antibody''' and '''Antibody-dependent cell mediated cytotoxicity (ADCC)'''. [[Immunoglobulins|Antibody]]-labelled cells can be targeted by [[Lymphocytes#Natural Killer (NK) cells|NK Cells]] as another defence against viral infection.  The antibody produced against viral protein can attach to infected cells during their budding phase, which effectively labels them for [[Lymphocytes#Natural Killer (NK) cells|NK]] targeting. [[Lymphocytes#Natural Killer (NK) cells|NK]] cells express Fc&gamma; receptors with which to detect such cells.  Once activated, they release a host of enzymes to induce apoptosis of the budding cell.
+The humoral response to viruses involves the production of '''neutralising antibody''' and '''Antibody-dependent cell mediated cytotoxicity (ADCC)'''. [[Immunoglobulins|Antibody]]-labelled cells can be targeted by [[Lymphocytes#Natural Killer (NK) cells|NK Cells]] as another defence against viral infection. The antibody produced against viral protein can attach to infected cells during their budding phase, which effectively labels them for [[Lymphocytes#Natural Killer (NK) cells|NK]] targeting. [[Lymphocytes#Natural Killer (NK) cells|NK]] cells express Fc&gamma; receptors with which to detect such cells. Once activated, they release a host of enzymes to induce apoptosis of the budding cell.
 ==Cell-Mediated==
-The cell-mediated response to viruses involves [[Lymphocytes#Cytotoxic CD8+|CD8+ T-cell]] mediated killing of virus infected cells. They are the main cells involved in the immune response to '''intracellular''' virus infection. Viruses are detected by the recognition of [[Major Histocompatability Complexes#MHC I|MHC I]]-peptide complex and infected cells are killed by apoptosis. perforin and granzymes activate the caspase cascade and Fas-ligand triggers the Fas-mediated apoptosis pathway. Cytotoxic [[Cytokines|cytokines]] (especially TNF-α & TNF-β lymphotoxin) act on TNF receptors to induce programmed cell death.
+The cell-mediated response to viruses involves [[Lymphocytes#Cytotoxic CD8+|CD8+ T-cell]] mediated killing of virus infected cells. They are the main cells involved in the immune response to '''intracellular''' virus infection. Viruses are detected by the recognition of [[Major Histocompatability Complexes#MHC I|MHC I]]-peptide complex and infected cells are killed by apoptosis. Perforin and granzymes activate the caspase cascade and Fas-ligand triggers the Fas-mediated apoptosis pathway. Cytotoxic [[Cytokines|cytokines]] (especially TNF-α & TNF-β lymphotoxin) act on TNF receptors to induce programmed cell death.
 [[Category:Adaptive Immune System]]

← Older revision		Revision as of 12:14, 18 October 2010
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−	[[Category:To Do - AimeeHicks]][[Category:To Do - Review]]	+	[[Category:To Do - AimeeHicks]][[Category:To Do - AP Review]]
	[[Category:Adaptive Immune System]]		[[Category:Adaptive Immune System]]

@@ Line 1: / Line 1: @@
-[[Image:virusimmunity.jpg|thumb|300px|right|'''''']]
+[[Image:virusimmunity.jpg|thumb|350px|right|'''''']]
@@ Line 12: / Line 12: @@
 The cell-mediated response to viruses involves [[Lymphocytes#Cytotoxic CD8+|CD8+ T-cell]] mediated killing of virus infected cells. They are the main cells involved in the immune response to '''intracellular''' virus infection. Viruses are detected by the recognition of [[Major Histocompatability Complexes#MHC I|MHC I]]-peptide complex and infected cells are killed by apoptosis. perforin and granzymes activate the caspase cascade and Fas-ligand triggers the Fas-mediated apoptosis pathway. Cytotoxic [[Cytokines|cytokines]] (especially TNF-α & TNF-β lymphotoxin) act on TNF receptors to induce programmed cell death.
 <big>'''Also see [[Immunity to Viruses]]'''</big>
-[[Category:To Do - AimeeHicks]]
+[[Category:To Do - AimeeHicks]][[Category:To Do - Review]]
 [[Category:Adaptive Immune System]]