Arteriosclerosis - Revision history

Bara at 14:22, 15 October 2013

2013-10-15T14:22:15Z

Bara at 16:18, 15 February 2011

2011-02-15T16:18:36Z

Eca02csb at 20:55, 20 August 2010

2010-08-20T20:55:32Z

Bara at 13:05, 1 July 2010

2010-07-01T13:05:57Z

Bara at 12:45, 1 July 2010

2010-07-01T12:45:53Z

Bara: New page: Encompasses a group of diseases characterised by degeneration of the arterial walls with fibrous thickening. The disease is chronic and non-inflammatory. As the vessels lose their elasti...

2010-07-01T12:44:09Z

New page: Encompasses a group of diseases characterised by degeneration of the arterial walls with fibrous thickening. The disease is chronic and non-inflammatory. As the vessels lose their elasti...

New page

Encompasses a group of diseases characterised by degeneration of the arterial walls with fibrous thickening. The disease is chronic and non-inflammatory. As the vessels lose their elasticity the lumen becomes narrowed and the end result is ischaemia if the tissue bed supplied.
[[Image:Arteriosclerosis.jpg|right|thumb|125px|<small><center>'''Arteriosclerosis'''. Courtesy of A. Jefferies</center></small>]]
''Incidence:''
*Horse: mainly in the aorta and branch points of arteries.
*Dog: commonly seen in th myocardium. Contributes to myocardial scarring and damage preceding myocardial failure.
*Also occurs in cattle.

Thought to be aetiologically related to haemodynamic damage to the endothelial layer. Perhaps initiated by:
*Platelet endothelial interaction.
*Plasma constituents entering the sub-endothelial layer.

Changes may be:

====Hyperplastic====

Chronically raised intraluminal pressure stimulates hyperplasia of the smooth muscle layer, reducing the size of the vessel lumen.
The elastic lamina may become duplicated or split allowing penetration of hyperplastic smooth muscle cells into the intima. Fibrous plaques form.

====Hyaline====
[[Image:Arterial hyalinisation.jpg|right|thumb|125px|<small><center>'''Aterial hyalinisation'''. Courtesy of A. Jefferies</center></small>]]
May occur alongside hyperplastic lesions or alone as a primary lesion. The intima becomes more permeable, allowing penetration of plasma contents into the vessel wall which becomes degenerate.

A combination of hyerplastic and hyaline change is often seen in the coronary arteries of the dog. Associated with ischaemic necrosis of the myocardium and therefore heart failure.

Also seen in uterine and ovarian arteries of pregnant animals. Thought to be clinically insignificant but indicated raised intraluminal pressure.
[[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Arterial_Pathology]]

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 Also seen in uterine and ovarian arteries of pregnant animals.  Thought to be clinically insignificant but indicated raised intraluminal pressure.
-==Test yourself with the Vascular Pathology Flashcards==
+{{Learning
+|flashcards = [[Vascular Pathology Flashcards]]
-[[Vascular Pathology Flashcards]]
+}}
 [[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Arterial_Pathology]]
 [[Category:To_Do_-_Cardiovascular]]
 [[Category:Cardiovascular_System_-_Degenerative_Pathology]]

@@ Line 27: / Line 27: @@
 ==Test yourself with the Vascular Pathology Flashcards==
-[[Vascular_Pathology_Flashcards_-_Pathology|Vascular Pathology Flashcards]]
+[[Vascular Pathology Flashcards]]
 [[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Arterial_Pathology]]
 [[Category:To_Do_-_Cardiovascular]]
 [[Category:Cardiovascular_System_-_Degenerative_Pathology]]

@@ Line 24: / Line 24: @@
 Also seen in uterine and ovarian arteries of pregnant animals.  Thought to be clinically insignificant but indicated raised intraluminal pressure.
 [[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Arterial_Pathology]]
 [[Category:To_Do_-_Cardiovascular]]
 [[Category:Cardiovascular_System_-_Degenerative_Pathology]]

← Older revision		Revision as of 13:05, 1 July 2010
Line 26:		Line 26:
	[[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Arterial_Pathology]]		[[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Arterial_Pathology]]
	[[Category:To_Do_-_Cardiovascular]]		[[Category:To_Do_-_Cardiovascular]]
		+	[[Category:Cardiovascular_System_-_Degenerative_Pathology]]

← Older revision		Revision as of 12:45, 1 July 2010
Line 25:		Line 25:
	Also seen in uterine and ovarian arteries of pregnant animals. Thought to be clinically insignificant but indicated raised intraluminal pressure.		Also seen in uterine and ovarian arteries of pregnant animals. Thought to be clinically insignificant but indicated raised intraluminal pressure.
	[[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Arterial_Pathology]]		[[Category:Cardiovascular_System_-_Vascular_Pathology]][[Category:Arterial_Pathology]]
		+	[[Category:To_Do_-_Cardiovascular]]