Basophils - Revision history

Rjfrancisrvc: /* Interactions */

2012-05-28T11:56:28Z

Interactions

Tianchee: /* Actions */

2011-06-18T18:40:08Z

Actions

Ctrace at 11:25, 22 February 2011

2011-02-22T11:25:57Z

Ctrace at 11:25, 22 February 2011

2011-02-22T11:25:05Z

Ctrace at 11:23, 22 February 2011

2011-02-22T11:23:43Z

Ctrace at 11:22, 22 February 2011

2011-02-22T11:22:58Z

Kate English at 12:44, 16 February 2011

2011-02-16T12:44:04Z

Suzannah.stacey at 17:44, 21 September 2010

2010-09-21T17:44:52Z

Suzannah.stacey: /* Development */

2010-09-21T17:34:27Z

Development

Suzannah.stacey: /* Introduction */

2010-09-21T13:01:37Z

Introduction

@@ Line 29: / Line 29: @@
 *[[IgE]] and CD40 receptors on the basophils interact with B cells to increase [[IgE]] production
-*Il-8 released by [[Neutrophils|neutrophils]] attracts basophils
+*IL-8 released by [[Neutrophils|neutrophils]] attracts basophils
 *[[Complement]] factor C3a binds to the basophil and causes degranulation

@@ Line 20: / Line 20: @@
 == Actions  ==
-Fc receptors on the basophil surface binds with IgE formed during allergic reactions and causes them to degranulate. The vasoactive substances released from the granules causes vasodialtion allowing for the infiltration of other leukocytes i.e. [[Neutrophils#Movement|neutrophil diapedesis]].
+Fc receptors on the basophil surface binds with IgE formed during allergic reactions and causes them to degranulate. The vasoactive substances released from the granules causes vasodilation allowing for the infiltration of other leukocytes i.e. [[Neutrophils#Movement|neutrophil diapedesis]].
 === Role in pathology  ===

← Older revision		Revision as of 11:25, 22 February 2011
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	<br>		<br>

−	[[Category:Blood_Cells]] [[Category:~~Kate_English_reviewed~~]]	+	[[Category:Blood_Cells]] [[Category:Kate_English_reviewing]]

← Older revision		Revision as of 11:25, 22 February 2011
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	<br>		<br>

−	[[Category:Blood_Cells]] [[Category:~~Kate_English_reviewing~~]]	+	[[Category:Blood_Cells]] [[Category:Kate_English_reviewed]]

@@ Line 3: / Line 3: @@
 == Introduction  ==
-Basophils are derived from the same stem cell line as [[Mast Cells|mast cells]] and while they are similar to mast cells, they are not identical (they are thought by some to be immature mast cells). They are the least common of all the [[Leukocytes|leukocytes]], are a similar size to neutrophils and eosinophils and are characterised by the large number of basophilic staining granules in their cytoplassm. They are present in the circulation but rarely found in tissue.
+Basophils are derived from the same stem cell line as [[Mast Cells|mast cells]] and while they are similar to mast cells, they are not identical (they are thought by some to be immature mast cells). They are the least common of all the [[Leukocytes|leukocytes]], are a similar size to neutrophils and eosinophils and are characterised by the large number of basophilic staining granules in their cytoplasm. They are present in the circulation but rarely found in tissue.
 == Development  ==

@@ Line 1: / Line 1: @@
 [[Image:LH Basophil Histology.jpg|thumb|right|150px|<p><b>Basophil</b></p><sup>©RVC 2008</sup>]] [[Image:LH Avian Basophil Histology.jpg|thumb|right|150px|<p><b>Avian Basophil</b></p><sup>©RVC 2008</sup>]]
-== Introduction ==
+== Introduction  ==
-Basophils are derived from the same stem cell line as [[Mast Cells|mast cells]] and while they are similar to mast cells, they are not identical (they are thought by some to be immature mast cells). They are the least common of all the [[Leukocytes|leukocytes]], are a similar size to neutrophils and eosinophils and are characterised by the large number of basophilic staining granules in their cytoplasm. They are present in the circulation but rarely found in tissue.
+Basophils are derived from the same stem cell line as [[Mast Cells|mast cells]] and while they are similar to mast cells, they are not identical (they are thought by some to be immature mast cells). They are the least common of all the [[Leukocytes|leukocytes]], are a similar size to neutrophils and eosinophils and are characterised by the large number of basophilic staining granules in their cytoplassm. They are present in the circulation but rarely found in tissue.
-== Development ==
+== Development  ==
 The basophil is a [[Blood Cells - Overview|granulocyte]] and has a similar development to the other granulocytes. This process is called [[Leukopoiesis#Granulopoiesis|granulopoiesis]].
-== Granules ==
+== Granules  ==
 Two types of granules are present in basophils:
@@ Line 16: / Line 16: @@
 *Specific granules contain heparin, histamine, leukotrienes and some lysosomes. Heparin has anti-coagulative capabilities and is also involved in assisting lipid uptake from the blood after meals. Histamine causes vasodilation.
-== Actions ==
+Fc receptors on the basophil surface binds with IgE formed during allergic reactions and causes them to degranulate. The vasoactive substances released from the granules causes vasodialtion allowing for the infiltration of other leukocytes i.e. [[Neutrophils#Movement|neutrophil diapedesis]].
-Fc receptors on the basophil surface binds with IgE formed during allergic reactions and causes them to degranulate. The vasoactive substances released from the granules causes vasodialtion allowing for the infiltration of other leukocytes i.e. [[Neutrophils#Movement|neutrophil diapedesis]].
+=== Role in pathology  ===
 *Classically a cell involved in [[Acute Inflammation|acute inflammation]]
-== Interactions ==
+== Interactions  ==
 *[[IgE]] and CD40 receptors on the basophils interact with B cells to increase [[IgE]] production
@@ Line 32: / Line 32: @@
 *[[Complement]] factor C3a binds to the basophil and causes degranulation
 <br>
-[[Category:Blood_Cells]] [[Category:Kate English reviewing]]
+[[Category:Blood_Cells]] [[Category:Kate_English_reviewing]]

@@ Line 5: / Line 5: @@
 ==Development==
-<p>The basophil is a [[Granulocytes|granulocyte]] and has a similar development to the other [[Granulocytes|granulocytes]]. This process is called [[Leukopoiesis#Granulopoiesis|granulopoiesis]] and further details can be found [[Leukopoiesis#Basophils|here]].</p>
+The basophil is a [[Blood Cells - Overview|granulocyte]] and has a similar development to the other granulocytes. This process is called [[Leukopoiesis#Granulopoiesis|granulopoiesis]].
 ==Granules==

@@ Line 2: / Line 2: @@
 [[Image:LH Avian Basophil Histology.jpg|right|thumb|150px|<p>'''Avian Basophil'''</p><sup>©RVC 2008</sup>]]
 ==Introduction==
-Basophils are derived from the same stem cell line as [[Mast Cells|mast cells]] and while they are similar to [[Mast Cells|mast cells]], they are not identical (thought by some to be immature mast cells). They are the least common of all the [[Leukocytes|leukocytes]], are a similar size to neutrophils and eosinophils and are characterised by the large number of basophilic staining granule in their cytoplasm. They are present in circulation but rarely found in tissue.
+Basophils are derived from the same stem cell line as [[Mast Cells|mast cells]] and while they are similar to mast cells, they are not identical (they are thought by some to be immature mast cells). They are the least common of all the [[Leukocytes|leukocytes]], are a similar size to neutrophils and eosinophils and are characterised by the large number of basophilic staining granules in their cytoplasm. They are present in the circulation but rarely found in tissue.
 ==Development==
 <p>The basophil is a [[Granulocytes|granulocyte]] and has a similar development to the other [[Granulocytes|granulocytes]]. This process is called [[Leukopoiesis#Granulopoiesis|granulopoiesis]] and further details can be found [[Leukopoiesis#Basophils|here]].</p>