Bone Marrow - Revision history

Bara at 19:16, 28 June 2012

2012-06-28T19:16:45Z

Bara at 15:27, 16 March 2012

2012-03-16T15:27:46Z

Ggaitskell at 07:54, 21 July 2011

2011-07-21T07:54:50Z

Bara: /* Others */

2011-01-06T17:17:23Z

Others

Bara: /* Introduction */

2011-01-06T17:16:40Z

Introduction

Bara at 17:16, 6 January 2011

2011-01-06T17:16:21Z

Bara at 16:31, 6 January 2011

2011-01-06T16:31:52Z

Bara at 16:30, 6 January 2011

2011-01-06T16:30:56Z

Bara: /* Others */

2011-01-06T14:30:54Z

Others

Bara at 14:27, 6 January 2011

2011-01-06T14:27:33Z

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 [[Image:LH Bone Marrow 1 Histology.jpg|thumb|200px|'''Bone Marrow''' ©RVC 2008]]
 ==Introduction==
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 <br><br>
 {{Jim Bee 2007}}
 [[Category:Primary Lymphoid Tissue]]
 [[Category:Bone and Cartilage - Anatomy & Physiology]]
 [[Category:A&P Done]]

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 |dragster = [[Blood Histology Resource (IV)|Bone Marrow Histology Dragster]]
 }}
+<br><br>
 [[Category:Primary Lymphoid Tissue]]
 [[Category:Bone and Cartilage - Anatomy & Physiology]]
 [[Category:A&P Done]]

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 ===Others===
 Bone marrow is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation#Plasma cells|plasma cells]]) reside there. [[Macrophages|Macrophages]] and [[T cell differentiation#Dendritic Cells|dendritic cells]] in the marrow remove foreign substance from the blood, a process which also occurs in the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]] and [[Liver - Anatomy & Physiology#Functions|liver]].
 [[Category:Primary Lymphoid Tissue]]
 [[Category:Bone and Cartilage - Anatomy & Physiology]]
 [[Category:A&P Done]]

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 ===Others===
-Bone marrow is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation#Plasma cells|plasma cells]]) reside there. [[Macrophages|Macrophages]] and [[T cell differentiation#Dendritic Cells|dendritic cells]] in the marrow remove foreign substance from the blood, a process which also occurs in the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]] and [[Liver - Anatomy & Physiogy#Functions|liver]].
+Bone marrow is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation#Plasma cells|plasma cells]]) reside there. [[Macrophages|Macrophages]] and [[T cell differentiation#Dendritic Cells|dendritic cells]] in the marrow remove foreign substance from the blood, a process which also occurs in the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]] and [[Liver - Anatomy & Physiology#Functions|liver]].
 [[Category:Primary Lymphoid Tissue]]
 [[Category:Bone and Cartilage - Anatomy & Physiology]]
 [[Category:A&P Done]]

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 [[Image:LH Bone Marrow 1 Histology.jpg|thumb|200px|'''Bone Marrow''' ©RVC 2008]]
 ==Introduction==
-Bone marrow is referred to as [[#Red marrow|red]] or [[#Yellow marrow|yellow]]. Red bone marrow is involved with [[Haemostasis - Overview|haemostasis]] while yellow bone marrow is adipose tissue. Bone marrow occupies the cavities in [[Bones - Anatomy & Physiology#Types of Bone|long bones]] and spaces in [[Bones - Anatomy & Physiology#Lamellar bone|spongy bones]].
+Bone marrow is referred to as [[#Red marrow|red]] or [[#Yellow marrow|yellow]]. Red bone marrow is involved with [[Haemostasis|haemostasis]] while yellow bone marrow is adipose tissue. Bone marrow occupies the cavities in [[Bones - Anatomy & Physiology#Types of Bone|long bones]] and spaces in [[Bones - Anatomy & Physiology#Lamellar bone|spongy bones]].
 ==Development==

@@ Line 1: / Line 1: @@
 [[Image:LH Bone Marrow 1 Histology.jpg|thumb|200px|'''Bone Marrow''' ©RVC 2008]]
 ==Introduction==
-Bone marrow is referred to as [[#Red marrow|red]] or [[#Yellow marrow|yellow]]. Red bone marrow is involved with [[Haemostasis|haemostasis]] while yellow bone marrow is adipose tissue. Bone marrow occupies the cavities in [[Bones - Anatomy & Physiology#Types of Bone|long bones]] and spaces in [[Bones - Anatomy & Physiology#Lamellar bone|spongy bones]].
+Bone marrow is referred to as [[#Red marrow|red]] or [[#Yellow marrow|yellow]]. Red bone marrow is involved with [[Haemostasis - Overview|haemostasis]] while yellow bone marrow is adipose tissue. Bone marrow occupies the cavities in [[Bones - Anatomy & Physiology#Types of Bone|long bones]] and spaces in [[Bones - Anatomy & Physiology#Lamellar bone|spongy bones]].
 ==Development==
 <p>Pluripotential haematopoietic stem cells (PPSC) migrate into bones from the [[Haematopoiesis - Overview#Yolk Sac Phase|embryonic yolk sac]] and the [[Haematopoiesis - Overview#Foetal|foetal liver]] during development, a process called homing. The cells then associate closely with the connective tissues within the bone. The PPSCs continue to constantly divide in the bone marrow with one daughter cell remaining a pluripotential stem cell and the other daughter cells developing into multipotential haematopoietic stem cells. The multipotential stem cells also constantly divide with some daughter cells remaining stem cells and the other daughter cells developing into blood cells ([[Haematopoiesis - Overview|haematopoiesis]]).</p>
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 ==Yellow marrow==
 <p>In young animals the majority of marrow is red. However as the animal matures into an adult significant portions of the haematopoietic tissues is replaced by adipose tissue. In adults all of the marrow in the long bones is adipose tissue and significant portions of marrow in haematopoietically active bones is adipose tissue as well.</p>
 ==Functions==
 ''Functions refer to red marrow''
 === Haematopoietic===
-[[Image:LH Bone Marrow Erythroblasts Histology.jpg|thumb|125px|'''Developing erythrocytes''' ©RVC 2008]]
+[[Image:LH Bone Marrow Erythroblasts Histology.jpg|thumb|200px|'''Developing erythrocytes''' ©RVC 2008]]
 <p>The haematopoietic cells produce the vast majority of blood cells in the body ([[Haematopoiesis - Overview|haematopoiesis]]). In young animals this occurs in most bones in the body but in mature adults this is limited to membranous bones in the body.</p>
 <p>To enter circulation newly formed cells press against the sinusoid wall, temporally fusing to it and creating an opening. The cell then passes directly into the circulation and the membrane repairs itself. Mature [[Erythrocytes|erythrocytes]] immediately enter circulation, however the marrow stores [[Leukocytes|leukocytes]] and consequently contains around ten times more [[Leukocytes|leukocytes]] than found in circulation</p>
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 ===Lymphoid tissue===
 [[Image:LH Bone Marrow Granulocyte Histology.jpg|thumb|125px|'''Developing granulocytes''' ©RVC 2008]]
-*In some primates it acts as a [[:Category:Primary Lymphoid Tissue|primary lymphoid organ]]
+In some primates bone marrow acts as a [[:Category:Primary Lymphoid Tissue|primary lymphoid organ]]. Bone marrow is also a [[:Category:Secondary Lymphoid Tissue|secondary lympoid tissue]] in other species.
 <p>It has little involvement in the primary immune response, but the migration of [[B cell differentiation#Memory cells|memory cells]] into the marrow from the [[Spleen - Anatomy & Physiology|spleen]] and [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] means that during a subsequent exposure to an antigen it produces significant amounts of antibodies.</p>
 ===Others===
-*It is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation#Plasma cells|plasma cells]]) reside in the bone marrow
+Bone marrow is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation#Plasma cells|plasma cells]]) reside there. [[Macrophages|Macrophages]] and [[T cell differentiation#Dendritic Cells|dendritic cells]] in the marrow remove foreign substance from the blood, a process which also occurs in the [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]] and [[Liver - Anatomy & Physiogy#Functions|liver]].
 [[Category:Primary Lymphoid Tissue]]
 [[Category:Bone and Cartilage - Anatomy & Physiology]]

← Older revision		Revision as of 14:30, 6 January 2011
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	[[Category:Primary Lymphoid Tissue]]		[[Category:Primary Lymphoid Tissue]]
−	[[Category:Bone and Cartilage]]	+	[[Category:Bone and Cartilage - Anatomy & Physiology]]