Bovine Leukocyte Adhesion Deficiency - Revision history

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Bara at 22:41, 7 November 2010

2010-11-07T22:41:01Z

Bara: Text replace - "Category:To Do - Blood" to "Category:To Do - BloodCategory:To Do - Clinical"

2010-08-20T10:52:55Z

Text replace - "Category:To Do - Blood" to "Category:To Do - Blood Category:To Do - Clinical"

Bara: Created page with "(BLAD) Occurs in Holstein cattle Missence mutation of -Asp-128-Gly in CD18 molecule *Recurrent infection, e.g. pneumonia Category:Primary Innate Immunity Deficiencies [[Cat..."

2010-08-12T13:50:36Z

Created page with "(BLAD) *Occurs in Holstein cattle *Missence mutation of -Asp-128-Gly in CD18 molecule *Recurrent infection, e.g. pneumonia Category:Primary Innate Immunity Deficiencies [[Cat..."

New page

(BLAD)
*Occurs in Holstein cattle
*Missence mutation of -Asp-128-Gly in CD18 molecule
*Recurrent infection, e.g. pneumonia
[[Category:Primary Innate Immunity Deficiencies]]
[[Category:Cattle]]
[[Category:To Do - Blood]]

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 Also known as '''''BLAD'''''
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 Test the herd and eliminate carrier animals.
-== Literature Search ==
+{{Learning
 == References ==
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 {{review}}
 [[Category:Primary_Innate_Immunity_Deficiencies]] [[Category:Lymphoreticular_and_Haematopoietic_Diseases_-_Cattle]] [[Category:Expert_Review - Farm Animal]]

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 Also known as '''''BLAD'''''
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 Affected calves will appear normal at birth but then become clinically ill within the first few weeks. Life expectancy is generally not more than one year old.
 == Clinical Signs ==
 Chronic recurrent infections such as pneumonia, diarrhoea, dermatitis, gingivitis or vasculitis. The infection will always reappear, even following antibiotic doses usually high enough to cure the infection.
 == Diagnosis ==
 There are tests available in the US to diagnose heterozygous carriers and homozygous calves.
 == Control ==
 Test the herd and eliminate carrier animals.
 == Literature Search ==
@@ Line 30: / Line 24: @@
 <br> Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation). <br><br><br> [http://www.cabi.org/cabdirect/FullTextPDF/2010/20103049446.pdf '''Bovine leukocyte adhesion deficiency syndrome (BLAD): a recessive disorder in Holstein Friesian cattle - a review.''' Vijay Kumar; Ashwani Sharma; Agricultural Research Communication Centre, Karnal, India, Agricultural Reviews, 2009, 30, 4, pp 293-300, many ref. - '''Full Text Article''']
 == References ==
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+{{review}}
 [[Category:Primary_Innate_Immunity_Deficiencies]] [[Category:Lymphoreticular_and_Haematopoietic_Diseases_-_Cattle]] [[Category:Expert_Review - Farm Animal]]

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-Also known as "BLAD".
+{{review}}
-== Introduction<br> ==
+Also known as '''''BLAD'''''
-This is an autosomal recessive disorder seen in Holstein Cattle mainly in the USA and is caused by a missence mutation of -Asp-128-Gly in CD18 molecule. It is is characterised by premature death and chronic bacterial infections such as recurrent pneumonia. All animals with this mutation can be traced to sire many years ago. In the USA, around 15% of cattle have this mutation.
+== Introduction ==
-Affected calves will appear normal at birth but then become clinically ill within the first few weeks. Life expectancy is generally not more than one year old.<br>
+This is an autosomal recessive disorder seen in Holstein Cattle mainly in the USA and is caused by a missence mutation of -Asp-128-Gly in CD18 molecule. It is characterised by premature death and chronic bacterial infections such as recurrent [[:Category:Pneumonia|pneumonia]]. All animals with this mutation can be traced to sire many years ago. In the USA, around 15% of cattle have this mutation.
-<br>
+Affected calves will appear normal at birth but then become clinically ill within the first few weeks. Life expectancy is generally not more than one year old.
-Chronic recurrent infections such as pneumonia, diarrhoea, dermatitis, gingivitis or vasulitis. The infection will always reappear, even following doses usually high enough to cure the infection. <br>
+== Clinical Signs ==
-<br>
+Chronic recurrent infections such as pneumonia, diarrhoea, dermatitis, gingivitis or vasculitis. The infection will always reappear, even following antibiotic doses usually high enough to cure the infection.
-There are tests avaliable in the US to diagnose heterozygous carriers and homozygous calves.<br>
+== Diagnosis ==
-<br>
+There are tests available in the US to diagnose heterozygous carriers and homozygous calves.
-Test the herd and eliminate carrier animals.<br>
+== Control ==
-<br>
+Test the herd and eliminate carrier animals.
-Andrews, A.H, Blowey, R.W, Boyd, H and Eddy, R.G. (2004) Bovine Medicine (Second edition), Blackwell Publishing<br>
+== Literature Search ==
-Radostits, O.M, Arundel, J.H, and Gay, C.C. (2000) Veterinary Medicine: a textbook of the diseases of cattle, sheep, pigs, goats and horses Elsevier Health Sciences<br>
+[[Image:CABI logo.jpg|left|90px]]
-== Literature Search ==
+== References ==
-[[Category:Primary_Innate_Immunity_Deficiencies]] [[Category:Lymphoreticular_and_Haematopoietic_Diseases_-_Cattle]] [[Category:To_Do_-_Blood]] [[Category:To_Do_-_Review]]
+[[Category:Primary_Innate_Immunity_Deficiencies]] [[Category:Lymphoreticular_and_Haematopoietic_Diseases_-_Cattle]] [[Category:Expert_Review - Farm Animal]]

@@ Line 1: / Line 1: @@
-(BLAD)
+Also known as "BLAD".
-==Literature Search==
+== Introduction<br> ==
-Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
+Affected calves will appear normal at birth but then become clinically ill within the first few weeks. Life expectancy is generally not more than one year old.<br>
-[[Category:Primary Innate Immunity Deficiencies]]
+== Clinical Signs<br> ==
-[[Category:Lymphoreticular and Haematopoietic Diseases - Cattle]]
-[[Category:To Do - Blood]][[Category:To Do - Kate]]
+Chronic recurrent infections such as pneumonia, diarrhoea, dermatitis, gingivitis or vasulitis. The infection will always reappear, even following doses usually high enough to cure the infection. <br>

@@ Line 15: / Line 15: @@
 [[Category:Primary Innate Immunity Deficiencies]]
 [[Category:Lymphoreticular and Haematopoietic Diseases - Cattle]]
-[[Category:To Do - Blood]][[Category:To Do - Clinical]]
+[[Category:To Do - Blood]][[Category:To Do - Kate]]

@@ Line 3: / Line 3: @@
 *Missence mutation of -Asp-128-Gly in CD18 molecule
 *Recurrent infection, e.g. pneumonia
 [[Category:Primary Innate Immunity Deficiencies]]
 [[Category:Cattle]]
 [[Category:To Do - Blood]][[Category:To Do - Clinical]]