Category:Enteritis, Villus Atrophy - Revision history

Bara at 18:32, 15 February 2011

2011-02-15T18:32:36Z

Bara at 11:07, 6 June 2010

2010-06-06T11:07:20Z

Bara at 11:05, 6 June 2010

2010-06-06T11:05:32Z

Bara at 11:05, 6 June 2010

2010-06-06T11:05:03Z

Bara: /* Enteritis Particularly Associated with Villus Atrophy */

2010-06-06T11:03:10Z

Enteritis Particularly Associated with Villus Atrophy

Bara: Created page with '==Villus Atrophy== * Commonly seen in enteric disease. * Occurs when more enterocytes are lost than are produced in the crypts. * Causes malabsorption of nutrients and water. …'

2010-06-06T11:02:31Z

Created page with '==Villus Atrophy== * Commonly seen in enteric disease. * Occurs when more enterocytes are lost than are produced in the crypts. * Causes malabsorption of nutrients and water. …'

New page

==Villus Atrophy==

* Commonly seen in enteric disease.
* Occurs when more enterocytes are lost than are produced in the crypts.
* Causes malabsorption of nutrients and water.
* There are two main types of villus atrophy:

===Villus atrophy with intact/hypertrophic crypt glands===

* Insult affects the villus enterocytes leading to increased loss.
** Under mild insult, villi may fully regenerate.
** Severe insult leads to immature cells on the villus.
*** Secrete water and electrolytes into lumen.
* Examples include:
** '''Rotavirus, Coronavirus'''
*** Infect villus enterocytes.
** '''Coccidia'''
*** Infect surface enterocytes.
** '''Nematodes'''
*** Abrase surface.

===Villus atrophy with damage to crypts===

* The primary insult is to crypt cells.
** Crypt cell death leads to dilated gland lumens (cysts).
** Production is impaired, eventually leading to insufficient cells for villi.
* Enterocytes lost to lumen are replaced by increasingly immature cells.
** Gives rise to severe malabsorption.
* If damage is severe, erosions/ulcers may form which may eventually heal.
** Even if there are no ulcers, damage can be long-term
*** Causes long-term malabsorption.
* Examples include:
** '''Parvovirus'''
*** Target crypt cells.
** '''Lymphoma'''
*** Numerous neoplastic lymphocytes compress crypts.
** '''Cytotoxic chemicals'''
*** Dividing crypt cells are susceptible.

==Enteritis Particularly Associated with Villus Atrophy==

===[[Reoviridae#Rotaviruses|Rotavirus]]===

===[[Cryptosporidium|Cryptosporidium]]===

* Small coccidial parasite.
* Affects calf, lamb, piglet, kitten.
* Increasingly important as part of the neonatal [[Intestine Diarrhoea - Pathology|diarrhoea]] complex in calves.
* Zoonosis.

====Pathology====

=====Gross=====

* Intestines diffusely reddened, with fluid contents.

=====Histological=====

* Tiny parasites on surface of epithelium.
* Villus atrophy and fusion.
* Iinflammation (mainly lymphoid) in crypts and lamina propria.

[[Category:Intestine_-_Inflammatory_Pathology_by_Type]]

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 </b></big>
-|logo =
+|logo =path-logo.png
 }}
 [[Category:Intestine_-_Inflammatory_Pathology_by_Type]]

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-==Villus Atrophy==
+{{frontpage
+|pagetitle =Enteritis, Villus Atrophy
-* Commonly seen in enteric disease.
+|pagebody = * Commonly seen in enteric disease.
 * Occurs when more enterocytes are lost than are produced in the crypts.
 * Causes  malabsorption of nutrients and water.
-* There are two main types of villus atrophy:
+* There are two main types of villus atrophy, with and without damage to the crypts.
+|contenttitle =Content
-===[[Villus atrophy with intact/hypertrophic crypt glands]]===
+|contentbody =<big><b>
 [[Category:Intestine_-_Inflammatory_Pathology_by_Type]]

← Older revision		Revision as of 11:03, 6 June 2010
Line 47:		Line 47:
	===[[Cryptosporidium\|Cryptosporidium]]===		===[[Cryptosporidium\|Cryptosporidium]]===

−	* Small coccidial parasite.
−	* Affects calf, lamb, piglet, kitten.
−	* Increasingly important as part of the neonatal [[Intestine Diarrhoea - Pathology\|diarrhoea]] complex in calves.
−	* Zoonosis.

−	~~====Pathology====~~
−
−	~~=====Gross=====~~
−
−	* Intestines diffusely reddened, with fluid contents.
−
−	~~=====Histological=====~~
−
−	* Tiny parasites on surface of epithelium.
−	* Villus atrophy and fusion.
−	* Iinflammation (mainly lymphoid) in crypts and lamina propria.

	[[Category:Intestine_-_Inflammatory_Pathology_by_Type]]		[[Category:Intestine_-_Inflammatory_Pathology_by_Type]]

@@ Line 9: / Line 9: @@
-===Villus atrophy with damage to crypts===
+===[[Villus atrophy with damage to crypts]]===
-* The primary insult is to crypt cells.
 ==Enteritis Particularly Associated with Villus Atrophy==