Category:Paramyxoviridae - Revision history

Kitnmre at 00:00, 16 June 2016

2016-06-16T00:00:10Z

Suzannah.stacey at 09:23, 24 August 2010

2010-08-24T09:23:16Z

Bara at 16:32, 18 August 2010

2010-08-18T16:32:04Z

Bara: Text replace - "Category:To_Do_-_Viruses" to "Category:To_Do_-_Clinical/Viruses"

2010-07-30T12:27:36Z

Text replace - "Category:To_Do_-_Viruses" to "Category:To_Do_-_Clinical/Viruses"

Bara at 22:43, 26 June 2010

2010-06-26T22:43:59Z

Bara at 12:49, 23 May 2010

2010-05-23T12:49:26Z

Bara at 11:36, 22 May 2010

2010-05-22T11:36:24Z

Bara: /* Bovine */

2010-05-22T11:35:46Z

Bovine

Bara: /* Types and Subtypes */

2010-05-22T11:32:29Z

Types and Subtypes

Bara: /* Rodentia */

2010-05-22T11:20:53Z

Rodentia

← Older revision		Revision as of 00:00, 16 June 2016
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	}}		}}

		+
		+	{{Learning \|Vetstream = <p>[https://www.vetstream.com/canis/Content/Bug/bug00215.asp Canine Distemper]</p><p>[https://www.vetstream.com/canis/Content/Bug/bug00210.asp Canine Parainfluenza Virus 2]</p>}}

	[[Category:Viral Organisms]]		[[Category:Viral Organisms]]

← Older revision		Revision as of 09:23, 24 August 2010
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−	[[Category:~~Viruses~~]]	+	[[Category:Viral Organisms]]

← Older revision		Revision as of 16:32, 18 August 2010
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	}}		}}

−	~~==Morphology==~~
−	*Single-stranded negative-sense unsegmented RNA virus
−	*Reassortment and antigenic shift cannot occur
−	*Spike proteins include
−	**'''HN''' (Haemagglutinin and Neuraminidase)
−	**'''F''' (Fusion glycoprotein), which allows the virus to fuse directly to the plasma membrane and release its RNA
−	***F also causes syncitium to form, which aids diagnosis
−	***Host antibody response to the F protein is the basis for vaccination
−
−	~~==Virulence==~~
−	*Paramyxoviruses replicate in the epithelium of the upper respiratory tract as well as occasionally in the gut
−	**Sites of spike protein cleavage
−	*Virulence varies by virus, see below
−
−	~~==Types and Subtypes==~~
−	~~Paramoyxoviridae was reclassified in 2000 to include 2 subfamilies and 5 genera, of interest including:~~
−	*Subfamily: ''[[Paramyxovirinae]]'':
−
−	*Subfamily: ''[[Pneumovirinae]]''
−
−	~~==Antigenic Variation==~~
−	*Antigenic conservation allows some cross protection by vaccination:
−	**Conservation of major virus-specific F/HN antigens means vaccines protect against '''all isolates''' of the same virus
−	**Minor morbillivirus-specific epitopes on F allows some cross protection between '''canine distemper, measles, and rinderpest'''
−	*Antigenic "fingerprinting" is possible for some viruses based on minor variable epitopes of HN, F and NP on specific isolates as detected by monoclonal antibodies
−	**These are detected by immunostaining infected cells
−
−	~~=Other resources=~~
−	*[http://www.pitt.edu/~super1/lecture/lec3401/index.htm On line Paramyxoviridae lecture by P. Russell]

	[[Category:Viruses]]		[[Category:Viruses]]
−	~~[[Category:To_Do_-_Clinical/Viruses]]~~

← Older revision		Revision as of 12:27, 30 July 2010
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	[[Category:Viruses]]		[[Category:Viruses]]
−	[[Category:To_Do_-~~_Viruses~~]]	+	[[Category:To_Do_-_Clinical/Viruses]]

← Older revision		Revision as of 22:43, 26 June 2010
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	[[Category:Viruses]]		[[Category:Viruses]]
		+	[[Category:To_Do_-_Viruses]]

← Older revision		Revision as of 12:49, 23 May 2010
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−	{{~~unfinished~~}}	+	{{frontpage
		+	\|pagetitle =Paramyxoviridae
		+	\|pagebody =
		+	\|contenttitle =Content
		+	\|contentbody =<big><b>
		+
		+	<categorytree mode=pages>Paramyxoviridae</categorytree>
		+	\|logo =
		+	}}

	==Morphology==		==Morphology==

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 *Antigenic "fingerprinting" is possible for some viruses based on minor variable epitopes of HN, F and NP on specific isolates as detected by monoclonal antibodies
 **These are detected by immunostaining infected cells
 =Other resources=

@@ Line 39: / Line 39: @@
 ==Bovine==
-===[[Bovine Parainfluenza - 3 (PI-3)]]===
+===[[Bovine Parainfluenza - 3]]===
-===[[Bovine Respiratory Syncytial Virus (BRSV)]]===
+===[[Bovine Respiratory Syncytial Virus]]===
 ==Equine==

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 *Subfamily: ''[[Paramyxovirinae]]'':
-*Subfamily: ''Pneumovirinae''
+*Subfamily: ''[[Pneumovirinae]]''
 ==Antigenic Variation==

@@ Line 55: / Line 55: @@
 ==Rodentia==
-===Murine Parainfluenza - 1 (Sendai virus)===
+===Murine Parainfluenza - 1 ([[Sendai Virus]])===
 =Other resources=