Category:Yersinia species - Revision history

Bara at 10:42, 25 June 2010

2010-06-25T10:42:45Z

A.allison at 12:31, 12 June 2010

2010-06-12T12:31:44Z

Bara at 11:27, 6 June 2010

2010-06-06T11:27:40Z

Bara at 13:11, 24 May 2010

2010-05-24T13:11:40Z

Bara at 13:43, 12 May 2010

2010-05-12T13:43:36Z

Bara at 13:42, 12 May 2010

2010-05-12T13:42:07Z

Bara: Created page with 'Category:Enterobacteriaceae'

2010-05-12T13:38:27Z

Created page with 'Category:Enterobacteriaceae'

New page

[[Category:Enterobacteriaceae]]

← Older revision		Revision as of 10:42, 25 June 2010
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	[[Category:Enterobacteriaceae]]		[[Category:Enterobacteriaceae]]
		+	[[Category:To_Do_-_Bacteria]]

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 *Survive in phagolysosomes and do not interfere with degranulation or lysosomal fusion
 *Resistant to macrophage killing mechanisms
-*Antiphagocytic proteins secreted by the organisms interfere with host [[Neutrophils - WikiBlood|neutrophils]]
+*Antiphagocytic proteins secreted by the organisms interfere with host [[Neutrophils|neutrophils]]
 *[[Yersinia pestis|''Y. pestis'']] is more invasive than the other species and also possesses and antiphagocytic capsule and a plasminogen activator which aids systemic spread; endotoxin also contributes to its pathogenicity
 *Transport within macrophages to mesenteric lymph nodes

@@ Line 10: / Line 10: @@
 ===Overview===
-*Cause [[Intestine Pathogens - Pathology|intestinal disease]] in animals and are important zoonoses
+*Cause intestinal disease in animals and are important zoonoses
 *10 species of which [[Yersinia pestis|''Y. pestis'']], [[Yersinia pseudotuberculosis|''Y. pseudotuberculosis]] and [[Yersinia enterocolitica|''Y. enterocolitica'']] are pathogenic to animals and humans; [[Yersinia pestis|''Y. pestis'']] is the most pathogenic
 *Rodents provide a reservoir of [[Yersinia pestis|''Y. pestis'']], which is the cause of human plague; fleas transmit the infection to other animals and humans

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-{{review}}
+{{frontpage
 ===Overview===
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 *Replication in lymph nodes and development of necrotic lesions, with neutrophil invasion
 *The bacteria destroy the macrophages causing septicaemia
 ===Diagnosis===
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 *Biochemical tests to identify particular species
 *Specific fluorescent antibody staining of lymph node aspirates to identify ''Y. pestis''
 ===Control===
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 *Control ''Y. pestis'' by controlling rodent population and flea control of cats
 *Control of other ''Yersinia'' species difficult due to their ubiquity
 ===Treatment===

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 ===Clinical infections===
-*''[[Yersinia pestis]]''
+<big>'''''<ncl style=bullet maxdepth=2 headings=bullet headstart=2 showcats=1 showarts=1>Category:{{PAGENAME}}</ncl></big>
 ===Diagnosis===

← Older revision		Revision as of 13:42, 12 May 2010
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		+	{{review}}
		+
		+	===Overview===
		+	*Cause [[Intestine Pathogens - Pathology\|intestinal disease]] in animals and are important zoonoses
		+	*10 species of which [[Yersinia pestis\|''Y. pestis'']], [[Yersinia pseudotuberculosis\|''Y. pseudotuberculosis]] and [[Yersinia enterocolitica\|''Y. enterocolitica'']] are pathogenic to animals and humans; [[Yersinia pestis\|''Y. pestis'']] is the most pathogenic
		+	*Rodents provide a reservoir of [[Yersinia pestis\|''Y. pestis'']], which is the cause of human plague; fleas transmit the infection to other animals and humans
		+	*[[Yersinia pseudotuberculosis\|''Y. pseudotuberculosis'']] and [[Yersinia enterocolitica\|''Y. enterocolitica'']] reside in the intestine of domestic and wild animals and birds
		+	*Birds may cause mechanical transfer of the organisms
		+
		+
		+	===Characteristics===
		+
		+	*Enterobacteria, but grow more slowly and at lower temperatures than other enterobacteria
		+	*Gram negative, non-spore forming, facultative anaerobes - rods or colibacilli
		+	*Non-lactose fermentors
		+	*Facultative intracellular pathogens
		+	*Show bipolar staining in Giemsa-stained smears from animal tissue
		+	*Pathogenic strains identified by serotyping and biotyping
		+
		+
		+	===Pathogenesis===
		+
		+	*[[Yersinia enterocolitica\|''Y. enterocolitica'']] and [[Yersinia pseudotuberculosis\|''Y. pseudotuberculosis'']] enter the intestinal mucosa via M cells of the Peyer's patches
		+	*Engulfed by macrphages in the mucosa
		+	*All three invasive species are facultative intracellular organisms and grow inside macrophages
		+	*Plasmid and chromosomal-encoded virulence factors required for survival and multiplication in macrophages
		+	*Survive in phagolysosomes and do not interfere with degranulation or lysosomal fusion
		+	*Resistant to macrophage killing mechanisms
		+	*Antiphagocytic proteins secreted by the organisms interfere with host [[Neutrophils - WikiBlood\|neutrophils]]
		+	*[[Yersinia pestis\|''Y. pestis'']] is more invasive than the other species and also possesses and antiphagocytic capsule and a plasminogen activator which aids systemic spread; endotoxin also contributes to its pathogenicity
		+	*Transport within macrophages to mesenteric lymph nodes
		+	*Replication in lymph nodes and development of necrotic lesions, with neutrophil invasion
		+	*The bacteria destroy the macrophages causing septicaemia
		+
		+
		+	===Clinical infections===
		+
		+	*''[[Yersinia pestis]]''
		+
		+	*''[[Yersinia pseudotuberculosis]]''
		+
		+	*''[[Yersinia enterocolitica]]''
		+
		+	===Diagnosis===
		+
		+	*''Yersinia'' species grow on blood agar and MacConkey agar at room temperature.
		+	*''Y. pseudotuberculosis'' and ''Y. enerocolica'' are motile, unlike ''Y. pestis''
		+	*Biochemical tests to identify particular species
		+	*Specific fluorescent antibody staining of lymph node aspirates to identify ''Y. pestis''
		+
		+
		+	===Control===
		+
		+	*Control ''Y. pestis'' by controlling rodent population and flea control of cats
		+	*Control of other ''Yersinia'' species difficult due to their ubiquity
		+
		+
		+	===Treatment===
		+
		+	*Euthanase or isolate animals suspected of ''Y. pestis'' infection; Streptomycin, doxycycline, gentamicin or chloramphinol
		+	*Long-acting tetracyclines, trimethoprim-sulphonamides, aminoglycosides and chloramphicol effective against ''Y. pseudotuberculosis'' and ''Y. enterocolica''
		+
		+
		+
		+
		+
		+
	[[Category:Enterobacteriaceae]]		[[Category:Enterobacteriaceae]]