Coagulation Tests - Revision history

Fiorecastro at 13:29, 12 April 2022

2022-04-12T13:29:54Z

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JoeWright at 10:31, 25 March 2022

2022-03-25T10:31:36Z

Fiorecastro: /* Authors and References */

2022-03-15T17:31:48Z

Authors and References

Fiorecastro: /* Buccal Mucosal Bleeding Time (BMBT) */

2022-03-10T19:30:06Z

Buccal Mucosal Bleeding Time (BMBT)

Fiorecastro at 19:17, 10 March 2022

2022-03-10T19:17:18Z

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Bara at 17:53, 5 July 2012

2012-07-05T17:53:09Z

Bara: /* References */

2011-09-01T17:16:29Z

References

Bara at 17:16, 1 September 2011

2011-09-01T17:16:02Z

Siobhanbrade: /* Fibrin Degradation Products */

2011-08-30T09:06:47Z

Fibrin Degradation Products

Siobhanbrade: /* References */

2011-08-30T09:05:47Z

References

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 {{OpenPages}}
 [[Category:Blood Samples and Coagulation Tests]]
 [[Category:Clinical Pathology]]
 [[Category:Expert Review]]

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 This test is only validated for dogs. A study to evaluate the concentration of D-dimers in healthy and sick cats, with and without DIC, concluded that the assay had limited value for diagnosis of DIC in this species (Tholen I et al).
-== Authors and References ==
+{{Learning
 |literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Coagulation%22&occuring1=title&rowId=2&options2=AND&q2=tes*&occuring2=title&rowId=3&options3=AND&q3=&occuring3=freetext&x=65&y=9&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Coagulation Tests publications]
 |flashcards = [[Equine Internal Medicine Q&A 03]]
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 #Howard, M R and (2008) '''Haematology: an illustrated colour text''', ''Elsevier Health Sciences''.
 #Mair, TS & Divers, TJ (1997) '''Self-Assessment Colour Review Equine Internal Medicine''' ''Manson Publishing Ltd''

← Older revision		Revision as of 19:30, 10 March 2022
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	The BMBT is influenced by all the aspects of this phase, including vasoconstriction, platelet adherence and plately aggregation. Although this makes BMBT an effective screening test for the vascular/platelet (primary) phase of haemostasis, it also means it is not purely a test for thrombocytopathia, as it is often considered: BMBT depends on an intact vasospastic response and adequate platelet numbers as well as platelet function<sup>3</sup>. BMBT is a fairly crude test, and has been found to be normal in some patients with a known platelet function disorder and vice versa<sup>3</sup>. The results of this test therefore should be interpreted with some caution.		The BMBT is influenced by all the aspects of this phase, including vasoconstriction, platelet adherence and plately aggregation. Although this makes BMBT an effective screening test for the vascular/platelet (primary) phase of haemostasis, it also means it is not purely a test for thrombocytopathia, as it is often considered: BMBT depends on an intact vasospastic response and adequate platelet numbers as well as platelet function<sup>3</sup>. BMBT is a fairly crude test, and has been found to be normal in some patients with a known platelet function disorder and vice versa<sup>3</sup>. The results of this test therefore should be interpreted with some caution.
		+
		+	==== Protocol ====
		+
		+	* Restraint, sedation or anaesthesia may be required depending on the patient. Sedation by the s/c route is recommended due to the possibility of impaired haemostasis
		+	* With the patient in lateral recumbency, the upper lip is folded upwards and held in place with a bandage which is tight enough to result in vessel congestion. (See reference articles for a diagram of this procedure)
		+	* A standard incision is made in the buccal mucosa with the Surgicutt device selecting an area of mucosa without visible blood vessels. Place the device firmly against the buccal
		+
		+	mucosa but do not press. Depress the trigger, commence timing and remove the device approximately one second after triggering
		+
		+	* Blot the flow of blood at 5 second intervals with filter paper, being careful not to touch the edge of the wound, and record the time to cessation of bleeding. The BMBT is the mean bleeding time for the two incisions. If bleeding continues for >20 minutes then the bandage should be removed and timing stopped
		+
		+	==== Interpretation ====
		+	The normal time to cessation of bleeding is:
		+
		+	* 1.7 to 3.3 minutes in restrained, unsedated or unanaesthetised dogs
		+	* <4.3 minutes in sedated or anaesthetised dogs
		+	* <3.3 minutes in anaesthetised cats
		+
		+	A prolonged BMBT may be seen in cases of thrombocytopenia, severe azotaemia and von Willebrands disease. Dogs with coagulation defects may have a normal BMBT although prolonged rebleeding after primary haemostasis may be seen.
		+
		+	Protocol and Interpretation References: [[NationWide Laboratories]]

	=== Clot retraction ===		=== Clot retraction ===

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 Also known as: '''''coagulation profile — clotting profile — clotting tests — tests of haemostasis
 [[Image:Coagulation Cascade.jpg|thumb|right|350px|Coagulation cascade. Source: Wikimedia Commons; Author: Joe D (2007)]]
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 {{review}}
 [[Category:Blood Samples and Coagulation Tests]]
 [[Category:Clinical Pathology]]
 [[Category:Expert Review]]

← Older revision		Revision as of 17:16, 1 September 2011
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	[[Category:Blood Samples and Coagulation Tests]]		[[Category:Blood Samples and Coagulation Tests]]
	[[Category:Clinical Pathology]]		[[Category:Clinical Pathology]]
		+	[[Category:Expert Review]]