Complement Flashcards - Revision history

Rjfrancisrvc: /* Complement Fixation Pathways */

2012-05-24T08:20:21Z

Complement Fixation Pathways

Bara at 17:21, 17 March 2012

2012-03-17T17:21:16Z

Bara: Text replace - "Category:Flashcards - Immunology" to "Category:Immunology Flashcards"

2011-02-07T14:51:16Z

Text replace - "Category:Flashcards - Immunology" to "Category:Immunology Flashcards"

Bara: Text replace - "Category:Flash Cards - WikiBlood" to "Category:Flashcards - Immunology"

2010-08-13T13:01:27Z

Text replace - "Category:Flash Cards - WikiBlood" to "Category:Flashcards - Immunology"

Bara: moved Complement Flashcards - WikiBlood to Complement Flashcards

2010-08-13T12:28:49Z

moved Complement Flashcards - WikiBlood to Complement Flashcards

Bara at 12:16, 13 August 2010

2010-08-13T12:16:47Z

A.allison: Text replace - 'Complement - WikiBlood' to 'Complement'

2010-06-12T16:03:21Z

Text replace - 'Complement - WikiBlood' to 'Complement'

A.allison at 11:14, 20 February 2010

2010-02-20T11:14:47Z

Show changes

A.allison: New page: {{toplink |backcolour = FFE4E1 |linkpage =Complement - WikiBlood |linktext =COMPLEMENT |sublink1 =Flash Cards - WikiBlood |subtext1 =WIKIBLOOD FLASHCARDS |pagetype =Blood }} ==
2008-09-05T15:22:39Z

New page: {{toplink |backcolour = FFE4E1 |linkpage =Complement - WikiBlood |linktext =COMPLEMENT |sublink1 =Flash Cards - WikiBlood |subtext1 =WIKIBLOOD FLASHCARDS |pagetype =Blood }} ==<font color...

New page
{{toplink
|backcolour = FFE4E1
|linkpage =Complement - WikiBlood
|linktext =COMPLEMENT
|sublink1 =Flash Cards - WikiBlood
|subtext1 =WIKIBLOOD FLASHCARDS
|pagetype =Blood
}}

==Complement Fixation Pathways==
{| border="3" cellpadding="8"
!width="400"|'''Question'''
!width="400"|'''Answer'''
!width="150"|'''Article'''
|-
|<big>'''What are the names of the different pathways of the complement cascade?'''
|| <big>
'''''Classical'''''
'''''Alternative'''''
'''''Mannose-binding Lectin'''''
||[[Complement - WikiBlood#Compelment Fixation Pathways|Link to Answer Article]]
|-
|<big>'''Which immunoglobulins can activate the classical pathway?'''
|| <big>
'''''IgM'''''
'''''IgG'''''
||[[Complement - WikiBlood#Compelment Fixation Pathways|Link to Answer Article]]
|-
|<big>'''What are the components of the C1 complex'''
|| <big>
'''''C1q'''''
'''''C1r'''''
'''''C1s'''''
||[[Complement - WikiBlood#Compelment Fixation Pathways|Link to Answer Article]]
|-
|<big>'''Which two complexes bind to make the enzyme C3 convertase?'''
|| <big>
'''''C2b'''''
'''''C4b'''''
||[[Complement - WikiBlood#Compelment Fixation Pathways|Link to Answer Article]]
|-
|<big>'''What initiates the membrane attack complex (MAC)?'''
|| <big>
'''''C3b'''''
||[[Complement - WikiBlood#Compelment Fixation Pathways|Link to Answer Article]]
|-
|<big>'''What functions do the Ca fragments have?'''
|| <big>
'''''Chemotactic for neutrophils'''''
'''''Induces acute inflammation'''''
'''''Increases vascular permeability'''''
'''''Causes mast cell and basophil degranulation'''''
||[[Complement - WikiBlood#Compelment Fixation Pathways|Link to Answer Article]]
|-
|<big>'''What are efficient activators of the alternative pathway?'''
|| <big>
'''''Gram-negative bacteria'''''
'''''Yeasts'''''
'''''Fungi'''''
||[[Complement - WikiBlood#Alternative Pathway|Link to Answer Article]]
|-
|<big>'''What are the main functions of the alternative pathway?'''
|| <big>
'''''To coat bacteria with iC3b'''''
'''''To induce an acute inflammatory response'''''
||[[Complement - WikiBlood#Alternative Pathway|Link to Answer Article]]
|-
|<big>'''What are lectins?'''
|| <big>
'''''Proteins which bind carbohydrates'''''
||[[Complement - WikiBlood#MB-Lectin Pathway|Link to Answer Article]]
|-
|<big>'''What does MASP stand for?'''
|| <big>
'''''Mannose-binding lectin associated proteases'''''
||[[Complement - WikiBlood#MB-Lectin Pathway|Link to Answer Article]]
|}
 
 
==Complement Inhibitors==
{| border="3" cellpadding="8"
!width="400"|'''Question'''
!width="400"|'''Answer'''
!width="150"|'''Article'''
|-
|<big>'''Which complement inhibitor exorts control over the classical pathway and how does it function?'''
|| <big>
*'''''Delay acclerating factor (DAF)'''''
**'''''Increases the degredation of C1 esterase'''''
||[[Complement - WikiBlood#Complement Inhibitors|Link to Answer Article]]
|-
|<big>'''What do factors I and H do?'''
|| <big>
'''''Breaks down C3b'''''
'''''Controls positive feedback by inhibiting C3b¯Bb'''''
'''''Prevents the complement cascade from running to exhaustion every time it is activated'''''
||[[Complement - WikiBlood#Complement Inhibitors|Link to Answer Article]]
|-
|<big>'''Which complement inhibitor binds inflammatory immune complexes in the plasma, transporting them to the liver for phagocytosis?'''
|| <big>
'''''Complement receptor 1 (CR1)'''''
||[[Complement - WikiBlood#Complement Inhibitors|Link to Answer Article]]
|-
|<big>'''What does CD59 do?'''
|| <big>
'''''Prevents cell lysis and pore formation'''''
'''''It is a protective mechanism for cells'''''
||[[Complement - WikiBlood#Complement Inhibitors|Link to Answer Article]]
|}
 
 

==Functions of the Complement Cascade==
{| border="3" cellpadding="8"
!width="400"|'''Question'''
!width="400"|'''Answer'''
!width="150"|'''Article'''
|-
|<big>'''What are the stages of opsonisation?'''
|| <big>
'''''The complement system deposits a shell of protein on the bacterial cell surface, e.g. complement fragments'''''
'''''Complement fragments released are chemotactic for phagocytes'''''
'''''iC3b acts as a target for phagocytosis'''''
'''''Phagocytes bind with the complement fragments destroying the bacteria'''''
||[[Complement - WikiBlood#Functions|Link to Answer Article]]
|-
|<big>'''What role do complement fragments have to promote inflammation?'''
|| <big>
'''''Smaller complement fragments attract granulocytes to the site of inflammation'''''
'''''Smaller complement fragments stimulate the degranulation of granulocytes'''''
||[[Complement - WikiBlood#Functions|Link to Answer Article]]
|-
|<big>'''By which process can C5-C9 directly kill pathogens?'''
|| <big>
*'''''Cell lysis'''''
||[[Complement - WikiBlood#Functions|Link to Answer Article]]
|}

@@ Line 20: / Line 20: @@
 |q4=Which two complexes bind to make the enzyme C3 convertase?
 |a4=
-*C2b
+*C2a
 *C4b
 |l4=Complement#Compelment Fixation Pathways
@@ Line 26: / Line 26: @@
 |a5=C3b
 |l5=Complement#Compelment Fixation Pathways
-|q6=What functions do the Ca fragments have?
+|q6=What functions do the C fragments C3a, C4a, C5a and C2b have?
 |a6=
 *Chemotactic for neutrophils
@@ Line 51: / Line 51: @@
 |l10=Complement#MB-Lectin Pathway
 </FlashCard>
 ===Complement Inhibitors===
 <FlashCard questions="4">

@@ Line 92: / Line 92: @@
 </FlashCard>
+<br><br>
 [[Category:Immunology Flashcards]]

← Older revision		Revision as of 14:51, 7 February 2011
Line 93:		Line 93:


−	[[Category:Flashcards ~~- Immunology~~]]	+	[[Category:Immunology Flashcards]]

← Older revision		Revision as of 13:01, 13 August 2010
Line 93:		Line 93:


−	[[Category:~~Flash Cards~~ - ~~WikiBlood~~]]	+	[[Category:Flashcards - Immunology]]

@@ Line 1: / Line 1: @@
 ===Complement Fixation Pathways===
 <FlashCard questions="10">
@@ Line 98: / Line 91: @@
 |l3=Complement#Functions
 </FlashCard>

← Older revision	Revision as of 12:28, 13 August 2010
(No difference)

@@ Line 1: / Line 1: @@
 {{toplink
-|linkpage =Complement - WikiBlood
+|linkpage =Complement
 |linktext =COMPLEMENT
 |sublink1 =Flash Cards - WikiBlood
@@ Line 13: / Line 13: @@
 *Alternative
 *Mannose-binding Lectin
-|l1=Complement - WikiBlood#Compelment Fixation Pathways
+|l1=Complement#Compelment Fixation Pathways
 |q2=Which immunoglobulins can activate the classical pathway?
 |a2=
 *IgM
 *IgG
-|l2=Complement - WikiBlood#Compelment Fixation Pathways
+|l2=Complement#Compelment Fixation Pathways
 |q3=What are the components of the C1 complex
 |a3=
@@ Line 24: / Line 24: @@
 *C1r
 *C1s
-|l3=Complement - WikiBlood#Compelment Fixation Pathways
+|l3=Complement#Compelment Fixation Pathways
 |q4=Which two complexes bind to make the enzyme C3 convertase?
 |a4=
 *C2b
 *C4b
-|l4=Complement - WikiBlood#Compelment Fixation Pathways
+|l4=Complement#Compelment Fixation Pathways
 |q5=What initiates the membrane attack complex (MAC)?
 |a5=C3b
-|l5=Complement - WikiBlood#Compelment Fixation Pathways
+|l5=Complement#Compelment Fixation Pathways
 |q6=What functions do the Ca fragments have?
 |a6=
@@ Line 39: / Line 39: @@
 *Increases vascular permeability
 *Causes mast cell and basophil degranulation
-|l6=Complement - WikiBlood#Compelment Fixation Pathways
+|l6=Complement#Compelment Fixation Pathways
 |q7=What are efficient activators of the alternative pathway?
 |a7=
@@ Line 45: / Line 45: @@
 *Yeasts
 *Fungi
-|l7=Complement - WikiBlood#Alternative Pathway
+|l7=Complement#Alternative Pathway
 |q8=What are the main functions of the alternative pathway?
 |a8=
 *To coat bacteria with iC3b
 *To induce an acute inflammatory response
-|l8=Complement - WikiBlood#Alternative Pathway
+|l8=Complement#Alternative Pathway
 |q9=What are lectins?
 |a9=Proteins which bind carbohydrates
-|l9=Complement - WikiBlood#MB-Lectin Pathway
+|l9=Complement#MB-Lectin Pathway
 |q10=What does MASP stand for?
 |a10=Mannose-binding lectin associated proteases
-|l10=Complement - WikiBlood#MB-Lectin Pathway
+|l10=Complement#MB-Lectin Pathway
 </FlashCard>
 ===Complement Inhibitors===
@@ Line 64: / Line 64: @@
 *Delay acclerating factor (DAF)
 **Increases the degredation of C1 esterase
-|l1=Complement - WikiBlood#Complement Inhibitors
+|l1=Complement#Complement Inhibitors
 |q2=What do factors I and H do?
 |a2=
@@ Line 70: / Line 70: @@
 *Controls positive feedback by inhibiting C3b¯Bb
 *Prevents the complement cascade from running to exhaustion every time it is activated
-|l2=Complement - WikiBlood#Complement Inhibitors
+|l2=Complement#Complement Inhibitors
 |q3=Which complement inhibitor binds inflammatory immune complexes in the plasma, transporting them to the liver for phagocytosis?
 |a3=Complement receptor 1 (CR1)
-|l3=Complement - WikiBlood#Complement Inhibitors
+|l3=Complement#Complement Inhibitors
 |q4=What does CD59 do?
 |a4=
 *Prevents cell lysis and pore formation
 *It is a protective mechanism for cells
-|l4=Complement - WikiBlood#Complement Inhibitors
+|l4=Complement#Complement Inhibitors
 </FlashCard>
 ===Functions of the Complement Cascade===
@@ Line 88: / Line 88: @@
 *iC3b acts as a target for phagocytosis
 *Phagocytes bind with the complement fragments destroying the bacteria
-|l1=Complement - WikiBlood#Functions
+|l1=Complement#Functions
 |q2=What role do complement fragments have to promote inflammation?
 |a2=
 *Smaller complement fragments attract granulocytes to the site of inflammation
 *Smaller complement fragments stimulate the degranulation of granulocytes
-|l2=Complement - WikiBlood#Functions
+|l2=Complement#Functions
 |q3=By which process can C5-C9 directly kill pathogens?
 |a3=Cell lysis
-|l3=Complement - WikiBlood#Functions
+|l3=Complement#Functions
 </FlashCard>