https://en.wikivet.net/index.php?action=history&feed=atom&title=Copper_Toxicity 2026-08-27T00:15:14Z Revision history for this page on the wiki MediaWiki 1.35.0 https://en.wikivet.net/index.php?title=Copper_Toxicity&diff=115463&oldid=prev 2011-05-13T11:43:37Z

<p></p> <table class="diff diff-contentalign-left diff-editfont-monospace" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:43, 13 May 2011</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l44" >Line 44:</td> <td colspan="2" class="diff-lineno">Line 44:</td></tr> <tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*[[Liver - Anatomy &amp; Physiology|liver]] is small and fibrosed</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*[[Liver - Anatomy &amp; Physiology|liver]] is small and fibrosed</div></td></tr> <tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*jaundice is not a consistent feature</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*jaundice is not a consistent feature</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Hepatotoxicity,_Chronic]][[Category:Liver Diseases - Sheep]]</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Hepatotoxicity,_Chronic]][[Category:Liver Diseases - Sheep]]</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category:To_Do_-<del class="diffchange diffchange-inline">_Clinical</del>]][[Category:Liver Diseases - Dog]]</div></td><td class='diff-marker'>+</td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category:To_Do_-<ins class="diffchange diffchange-inline">_Alimentary]][[Category:To Do - Major</ins>]][[Category:Liver Diseases - Dog]]</div></td></tr> </table>

Bara https://en.wikivet.net/index.php?title=Copper_Toxicity&diff=105405&oldid=prev 2011-01-20T18:58:36Z

<p>Created page with &quot;==Hepatotoxicity== *sheep are very susceptible **they have poor ability to excrete copper in the bile *copper accumulates in hepatocytes until it reaches a critical level **the h...&quot;</p> <p><b>New page</b></p><div>==Hepatotoxicity==<br /> *sheep are very susceptible<br /> **they have poor ability to excrete copper in the bile<br /> *copper accumulates in hepatocytes until it reaches a critical level<br /> **the hepatocytes die and release the copper into the blood<br /> **causes haemolysis of the red blood cells<br /> *this haemolysis further damages the hepatocytes<br /> **releases even more copper<br /> ====Predisposing factors====<br /> *contamination of foodstuffs and pasture with copper<br /> *any damage to the biliary system as in ragwort poisoning<br /> *pastures low in molybdenum<br /> **increases the availability of dietary copper<br /> **molybdenum combines with copper to form insoluble complexes in the gut<br /> <br /> ====Gross====<br /> *carcass<br /> **jaundiced<br /> **reddish<br /> *[[Liver - Anatomy &amp; Physiology|liver]] <br /> **swollen<br /> **soft<br /> **orange in colour<br /> *[[Urinary System Overview - Anatomy &amp; Physiology#Upper Urinary Tract|kidneys]]<br /> **deep red<br /> **red urine due to haemoglobinuria<br /> <br /> ====Microscopically====<br /> *periacinar hepatic necrosis and profuse bile due to haemolysis and cholestasis<br /> *copper can be demonstrated with special stain - rhodanine<br /> <br /> ====Genetic inheritance====<br /> *Bedlington and West Highland White Terriers<br /> *copper toxicosis susceptibility<br /> *inherited as autosomal defect<br /> *copper levels can be very high in the [[Liver - Anatomy &amp; Physiology|livers]] of these animals<br /> *there is no haemolytic crisis<br /> <br /> =====Clinical=====<br /> *ill thrift<br /> *progressive neurological signs due to [[Liver - Anatomy &amp; Physiology|liver]] failure<br /> <br /> =====Gross=====<br /> *[[Liver - Anatomy &amp; Physiology|liver]] is small and fibrosed<br /> *jaundice is not a consistent feature<br /> <br /> [[Category:Hepatotoxicity,_Chronic]][[Category:Liver Diseases - Sheep]]<br /> [[Category:To_Do_-_Clinical]][[Category:Liver Diseases - Dog]]</div>

Bara