Dermatophytosis - Donkey - Revision history

Bara at 08:55, 20 October 2010

2010-10-20T08:55:41Z

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2010-03-18T12:17:10Z

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Bara at 13:02, 4 March 2010

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2010-02-25T10:20:40Z

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Bara at 15:23, 18 February 2010

2010-02-18T15:23:57Z

Bara: Protected "Dermatophytosis - Donkey" [edit=sysop:move=sysop]

2010-02-18T15:21:51Z

Protected "Dermatophytosis - Donkey" [edit=sysop:move=sysop]

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2010-02-18T15:21:45Z

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+==Introduction==
 ==Clinical signs==
-[[Image:Dermatophytosis donkey.jpg|right|thumb|200px|<small><center>A dermatophyte infection of the neck of a donkey. Note the lack of circular lesions commonly thought to be a characteristic feature of ‘ringworm’. (Image courtesy of  [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
+Donkeys present in the usual manner with '''centrifugally expanding roughly circular or coalescing patches of alopecia, scaling and mild exudation'''. There is seldom any significant pruritus, but the donkey may respond to gentle rubbing of the lesion with nose and mouth twitching suggesting some pleasurable relief. More extensive, less well defined areas
 may develop in cases affected with certain of the ''Trichophyton spp.''
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 Immunity is reasonably effective and repeat infection with the same organism should not occur for over two years. Vaccine technology has not yet reached the donkey!
 ==References==

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		+	==Clinical signs==
		+
		+	[[Image:Dermatophytosis donkey.jpg\|right\|thumb\|200px\|<small><center>A dermatophyte infection of the neck of a donkey. Note the lack of circular lesions commonly thought to be a characteristic feature of ‘ringworm’. (Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
		+	Donkeys are liable to [[Dermatophytosis\|dermatophyte]] (ringworm) infestation, but the clinical features are often less obvious than in horses. Ringworm due to ''Trichophyton'' and ''Microsporum'' dermatophytes are the most common fungal infection in
		+	most temperate climates and present in the usual manner with '''centrifugally expanding roughly circular or coalescing patches of alopecia, scaling and mild exudation'''. There is seldom any significant pruritus, but the donkey may respond to gentle rubbing of the lesion with nose and mouth twitching suggesting some pleasurable relief. More extensive, less well defined areas
		+	may develop in cases affected with certain of the ''Trichophyton spp.''
		+
		+	==Diagnosis==
		+
		+	Diagnosis is typically by '''hair pluckings''' from the active, outer margin of the lesion, or appropriately '''stained biopsies'''. Little is known of the range of dermatophytes affecting donkeys nor of any specific clinical features that
		+	might permit an informed guess as to the species involved in any particular case. Most cases are presented very late in the course of the disease and [[Bacterial Skin Infections - Donkey\|secondary bacterial infection]], self-trauma and often ill-advised attempts at treatment can result in complicated multifactorial dermatitis.
		+
		+	==Treatment==
		+
		+	The large majority of dermatophytosis cases '''resolve spontaneously''' (as in horses), but there may be a delay if the donkey is either immunocompromised or is malnourished. Topical treatment with [[Antifungal Drugs#The Azoles\|'''konazoles''']] (such as enilconazole, miconazole) or natamycin washes will help to clear the infection and limit the environmental contamination with the highly resistant spores.
		+
		+	<u>Oral [[Antifungal Drugs#Griseofulvin\|griseofulvin]] should probably be avoided.</u> It has no proven efficacy, it is expensive, it requires daily administration per os, and it has teratogenic properties for pregnant jennies.
		+
		+	==Control==
		+
		+	Environmental hygiene with individual tack, blankets and harnesses is a major aspect of the control of the disease. Spread to other donkeys must be prevented by good hygiene and isolation of affected cases. There are also important '''zoonotic aspects''' although most of the species identified in donkeys have a low zoonotic capability.
		+
		+	Immunity is reasonably effective and repeat infection with the same organism should not occur for over two years. Vaccine technology has not yet reached the donkey!
		+
		+	==References==
		+
		+	* Knottenbelt, D. (2008) Skin disorders In Svendsen, E.D., Duncan, J. and Hadrill, D. (2008) ''The Professional Handbook of the Donkey'', 4th edition, Whittet Books, Chapter 8
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