Diffuse Fibrosing Alveolitis - Revision history

Bara at 18:50, 19 February 2011

2011-02-19T18:50:53Z

Bara at 18:13, 19 February 2011

2011-02-19T18:13:28Z

Bara at 16:00, 19 February 2011

2011-02-19T16:00:05Z

Bara: Text replace - "Category:To Do - Blood" to "Category:To Do - BloodCategory:To Do - Clinical"

2010-08-20T10:54:38Z

Text replace - "Category:To Do - Blood" to "Category:To Do - Blood Category:To Do - Clinical"

Bara: Created page with "Diffuse Fibrosing Alveolitis/ Interstitial Pneumonia Diffuse inflammatory process which occurs distal to the terminal bronchioles Characterised by thickening and fibrosis of t..."

2010-08-11T14:24:34Z

Created page with "Diffuse Fibrosing Alveolitis/ Interstitial Pneumonia *Diffuse inflammatory process which occurs distal to the terminal bronchioles *Characterised by thickening and fibrosis of t..."

New page

Diffuse Fibrosing Alveolitis/ Interstitial Pneumonia

*Diffuse inflammatory process which occurs distal to the terminal bronchioles
*Characterised by thickening and fibrosis of the alveolar walls
*The precise underlying aetiology of this condition is obscure and it is likely to represent the end stage of a variety of initial insults including '''EAA''' and [[Lungs Inflammatory - Pathology#Acute bovine pulmonary emphysema and oedema (ABPEE)|fog fever]]
*Progression from an acute exudative phase through a proliferative phase (proliferation of type II pneumocytes) to a final irreversible stage of fibrosis is the hallmark of DFA
*The rate of the ensuing fibrosis is heavily dependant on the intensity of the inflammation associated with it
*Underlying pathogenesis of the fibrosis is complex and involves a relative increase of type I collagen fibres (dense, high tensile strength) over type III fibres (reticulin)
*Stimulation of fibroblast proliferation and collagen deposition are thought to be induced by macrophage derived cytokines, e.g. IL-1, TGFalpha and TGFbeta, GM-CSF

[[Category:Allergic Respiratory Diseases]][[Category:To Do - Blood]]

← Older revision		Revision as of 16:00, 19 February 2011
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	[[Category:Allergic Respiratory Diseases]][[Category:To Do - Blood]][[Category:To Do - Clinical]]		[[Category:Allergic Respiratory Diseases]][[Category:To Do - Blood]][[Category:To Do - Clinical]]
		+	[[Category:Type III Hypersensitivity Diseases]]
		+	[[Category:Bronchi and Bronchioles - Pathology]]
		+	[[Category:Respiratory System - Inflammatory Pathology]]

← Older revision		Revision as of 10:54, 20 August 2010
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−	[[Category:Allergic Respiratory Diseases]][[Category:To Do - Blood]]	+	[[Category:Allergic Respiratory Diseases]][[Category:To Do - Blood]][[Category:To Do - Clinical]]

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 *Diffuse inflammatory process which occurs distal to the terminal bronchioles
 *Characterised by thickening and fibrosis of the alveolar walls
-*The precise underlying aetiology of this condition is obscure and it is likely to represent the end stage of a variety of initial insults including '''EAA''' and [[Lungs Inflammatory - Pathology#Acute bovine pulmonary emphysema and oedema (ABPEE)|fog fever]]
+*The precise underlying aetiology of this condition is obscure and it is likely to represent the end stage of a variety of initial insults including '''EAA''' and [[Acute Bovine Pulmonary Emphysema and Oedema|fog fever]]
 *Progression from an acute exudative phase through a proliferative phase (proliferation of type II pneumocytes) to a final irreversible stage of fibrosis is the hallmark of DFA
 *The rate of the ensuing fibrosis is heavily dependant on the intensity of the inflammation associated with it