Feline Herpesvirus 1 - Revision history

BaraStudent: /* References */

2016-01-19T09:42:20Z

References

Bara at 09:17, 14 November 2014

2014-11-14T09:17:25Z

Gd49: /* Clinical Signs */

2014-02-20T16:22:45Z

Clinical Signs

Bara at 23:11, 7 August 2012

2012-08-07T23:11:36Z

Bara: /* Links */

2011-05-10T14:41:28Z

Links

Bara at 14:41, 10 May 2011

2011-05-10T14:41:12Z

Bara at 17:43, 21 March 2011

2011-03-21T17:43:32Z

Kthompson at 15:03, 17 March 2011

2011-03-17T15:03:04Z

Bara: Text replace - "[[Trachea Inflammatory - Pathology" to "[[Tracheitis"

2011-02-19T14:43:36Z

Text replace - "[[Trachea Inflammatory - Pathology" to "[[Tracheitis"

Bara at 16:27, 17 February 2011

2011-02-17T16:27:58Z

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 {{Learning
 |powerpoints = [[E-Lecture:Feline Herpesvirus-1]]
 }}

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 Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition), Merial
-== Links  ==
+{{Learning
+|powerpoints = [[E-Lecture:Feline Herpesvirus-1]]
-[http://www.abcd-vets.org/guidelines/feline_herpesvirus/index.asp ABCD information]
+}}

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 == Clinical Signs  ==
-Upper respiratory tract signs such as [[rhinitis]], [[tracheitis]] and [[sinusitis]] as well as keratitis and corneal ulcers. In combination with other agents, will cause 'cat flu' which will include sneezing, coughing, gummy eyes, nasal discharge, dyspnoea and conjunctivitis.
+Upper respiratory tract signs such as [[rhinitis]], [[tracheitis]] and [[sinusitis]] as well as keratitis and [[Corneal Ulceration - Dogs and Cats|corneal ulcers]]. The corneal ulcers intially have a '''dendritic''' appearence, which is considered pathognomic. In combination with other agents, will cause 'cat flu' which will include sneezing, coughing, gummy eyes, nasal discharge, dyspnoea and conjunctivitis.
 == Diagnosis  ==

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 == Introduction  ==
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 {{review}}
 [[Category:Herpesviridae]] [[Category:Expert_Review - Small Animal]] [[Category:Cat_Viruses]] [[Category:Respiratory_Diseases_-_Cat]] [[Category:Respiratory_Viral_Infections]]
 [[Category:Hepatitis, Viral]]

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+{{review}}
 [[Category:Herpesviridae]] [[Category:Expert_Review - Small Animal]] [[Category:Cat_Viruses]] [[Category:Respiratory_Diseases_-_Cat]] [[Category:Respiratory_Viral_Infections]]
 [[Category:Hepatitis, Viral]]

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 == Introduction  ==
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 The virus is widespread and common. It can cause serious infections as well as latent infections which can be reactivated on boarding or at other periods of stress.
 == Clinical Signs  ==
 Upper respiratory tract signs such as [[rhinitis]], [[tracheitis]] and [[sinusitis]] as well as keratitis and corneal ulcers. In combination with other agents, will cause 'cat flu' which will include sneezing, coughing, gummy eyes, nasal discharge, dyspnoea and conjunctivitis.
 == Diagnosis  ==
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 '''Nasal swabs''' on first week of infection can be cultured for virus isolation, plus a swab of the eye.
 == Treatment  ==
 For keratitis with corneal ulcers treat with subcutaneous omega interferon and give topical trifluorothymidine (thymidine analogue) on eyes.
 == Control  ==
 Killed and live '''[[vaccines]]''' are available. Live vaccines have provoked symptoms in immunosuppressed kittens and are no longer used in the UK.
 == References  ==
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 Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition), Merial
 == Links  ==
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-[[Category:Herpesviridae]] [[Category:Expert_Review]] [[Category:Cat_Viruses]] [[Category:Respiratory_Diseases_-_Cat]] [[Category:Respiratory_Viral_Infections]]
+[[Category:Herpesviridae]] [[Category:Expert_Review - Small Animal]] [[Category:Cat_Viruses]] [[Category:Respiratory_Diseases_-_Cat]] [[Category:Respiratory_Viral_Infections]]

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-{{unfinished}}
+== Introduction<br>  ==
-rarely causes skin infections
+Feline Herpes virus causes an upper respiratory tract infection: Feline Viral Rhinotracheitis.&nbsp;
-====Epidemiology====
+Viruses and bacteria are involved in the complex, with the most frequent aetiologic agent being FHV-1, and less frequently feline calicivirus and/or ''[[Chlamydophila psittaci]]''. All three agents infect URT respiratory epithelium, although FHV-1 has the highest affinity for this epithelium.&nbsp;Feline calicivirus more frequently infects the oral mucosa -&gt; ulcerative stomatitis and&nbsp;C.psittaci more frequently infects the conjunctival epithelium -&gt; chronic conjunctivitis. All three together will result in the disease complex 'cat flu'.
-====Diagnosis====
+Infection of the respiratory epithelium by FHV-1 results in a typical neutrophilic rhinitis with intraepitheial intranuclear eosinophilic inclusion bodies, with expected clinical signs. Resolution of these clinical signs usually occurs by 7-14 days, however, FHV-1 remains '''latent''' in the trigeminal ganglion, and can reactivate at times of stress: Can infect the cornea -&gt; ulcerative keratitis. FHV- 1 is the most common cause of keratitis and corneal ulcers in cats and gummy eyes in kittens.
-====Treatment====
+Occasional mortality can occur in the kitten or immunocompromised animals usually associated with secondary bacterial infections.&nbsp;
-====Control====
+The virus is widespread and common. It can cause serious infections as well as latent infections which can be reactivated on boarding or at other periods of stress.<span style="font-weight: bold;">
-*Killed and live '''vaccines''' are available
+</span>&lt;span style="font-weight: bold;" /&gt;
-===Feline viral rhinotracheitis===
+<br>
-*Caused by a [[Herpesviridae|herpesvirus]]
+== Clinical Signs  ==
-==Links==
+Upper respiratory tract signs such as rhinitis, tracheitis and sinusitis as well as keratitis and corneal ulcers. In combination with other agents, will cause 'cat flu' which will include sneezing, coughing, gummy eyes, nasal discharge, dyspnoea and conjunctivitis.
-[http://www.abcd-vets.org/guidelines/feline_herpesvirus/index.asp ABCD information]
+<br>
-[[Category:Herpesviridae]][[Category:To_Do_-_Clinical/Viruses]][[Category:Cat Viruses]][[Category:Respiratory Diseases - Cat]]
+Clinical signs and history are usually used as a presumptive diagnosis prior to defintive diagnosis via laboratory tests.
 [[Category:Respiratory_Viral_Infections]]

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 *Caused by a [[Herpesviridae|herpesvirus]]
-*Tends to be more [[Rhinitis#Infectious causes of rhinitis|rhinitis]] than [[Trachea Inflammatory - Pathology#Infectious causes of tracheitis|tracheitis]], may extend to [[Sinusitis|sinusitis]]
+*Tends to be more [[Rhinitis#Infectious causes of rhinitis|rhinitis]] than [[Tracheitis#Infectious causes of tracheitis|tracheitis]], may extend to [[Sinusitis|sinusitis]]
 *Feline herpesvirus -1
 **One of the causes of Feline viral rhinotracheitis