Immunoglobulin D - Revision history

Bara at 16:06, 2 July 2012

2012-07-02T16:06:09Z

2012-05-25T09:21:22Z

Function

2012-05-25T09:16:55Z

2012-05-25T09:15:24Z

Function

2012-03-16T15:58:50Z

2011-01-10T14:23:49Z

2011-01-09T14:40:25Z

2011-01-09T14:39:52Z

2011-01-09T14:38:42Z

2011-01-09T14:37:27Z

@@ Line 1: / Line 1: @@
 [[Image:LH IgD.png|thumb|250px|right|'''IgD''']]
 [[Image:IgD.jpg|thumb|right|250px|IgD - B. Catchpole, RVC 2008]]
 ''Shortened to IgD''.
@@ Line 29: / Line 29: @@
 <br><br>
 {{Jim Bee 2007}}
 [[Category:Immunoglobulins]]
 [[Category:A&P Done]]

← Older revision		Revision as of 09:21, 25 May 2012
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	IgD is only expressed in association with [[IgM]]. It is thought to be important in B-cell development, although it has been shown in δ chain knockout mice (so they have no functional IgD) do not have any noticeable defects in immune function.		IgD is only expressed in association with [[IgM]]. It is thought to be important in B-cell development, although it has been shown in δ chain knockout mice (so they have no functional IgD) do not have any noticeable defects in immune function.
		+	<p> Interestingly IgD serum levels increase in allergic reactions, although it is not known why this is.</p>

	==Links==		==Links==

@@ Line 9: / Line 9: @@
 ==Structure==
-IgD is Y-shaped. In rodents, it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.
+IgD is Y-shaped. In rodents, it has two δ heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.
 ==Function==

@@ Line 13: / Line 13: @@
 ==Function==
-IgD is only expressed in association with [[IgM]]. It is important in B-cell development.
+IgD is only expressed in association with [[IgM]]. It is thought to be important in B-cell development, although it has been shown in δ chain knockout mice (so they have no functional IgD) do not have any noticeable defects in immune function.
 ==Links==

@@ Line 26: / Line 26: @@
 [[Immunoglobulin M|Immunoglobulin M]]
+<br><br>
 [[Category:Immunoglobulins]]
 [[Category:A&P Done]]

← Older revision		Revision as of 14:23, 10 January 2011
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	[[Category:Immunoglobulins]]		[[Category:Immunoglobulins]]
−	[[Category:~~Image Review]]~~	+	[[Category:A&P Done]]
−	~~[[Category:To Do - AimeeHicks]][[Category:To Do - Review~~]]

@@ Line 3: / Line 3: @@
 ==Overview==
-''Shortened to IgD''
+''Shortened to IgD''.
 IgD is present in ruminants, pigs, dogs and rodents but has not been identified in horses, cats, rabbits and chickens.  It is mainly expressed on the surface of B-cells i.e. it is never secreted.
@@ Line 20: / Line 20: @@
 [[Immunoglobulin A|Immunoglobulin A]]
 [[Immunoglobulin E|Immunoglobulin E]]
@@ Line 31: / Line 29: @@
 [[Category:Immunoglobulins]]
 [[Category:Image Review]]
-[[Category:To Do - AimeeHicks]]
+[[Category:To Do - AimeeHicks]][[Category:To Do - Review]]

@@ Line 1: / Line 1: @@
 <br>
 <p>''Shortened to IgD''</p>
-[[Image:LH IgD.png|thumb|150px|right|'''IgD''']]
-[[Image:IgD.jpg|thumb|right|150px|IgD - B. Catchpole, RVC 2008]]
+[[Image:LH IgD.png|thumb|250px|right|'''IgD''']]
-<p>IgD is present in ruminants, pigs, (dogs) and rodents but has not been identified in horses, cats, rabbits and chickens.  It is mainly expressed on the surface of B-cells i.e. it is never secreted.</p>
 ==Structure==
-<p>IgD is Y-shaped and in rodents it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.</p>
 ==Function==
-<p>
-*IgD is only expressed in association with [[IgM]]
+IgD is only expressed in association with [[IgM]]. It is important in B-cell development.
 ----
 <center><b><sup>[[Immunoglobulins|Immunoglobulins]]: [[Immunoglobulin A|Immunoglobulin A]], [[Immunoglobulin D|Immunoglobulin D]], [[Immunoglobulin E|Immunoglobulin E]], [[Immunoglobulin G|Immunoglobulin G]] & [[Immunoglobulin M|Immunoglobulin M]]</sup></b></center>