Inclusion Body Rhinitis - Revision history

Bara at 14:00, 17 August 2012

2012-08-17T14:00:44Z

Bara: Text replace - "Category:CABI Expert Review Completed" to "Category:CABI Expert Review CompletedCategory:CABI AHPC Pages"

2012-04-13T15:09:54Z

Text replace - "Category:CABI Expert Review Completed" to "Category:CABI Expert Review Completed Category:CABI AHPC Pages"

Bara at 17:27, 22 December 2011

2011-12-22T17:27:20Z

Bara: /* References */

2011-09-29T21:49:01Z

References

Bara at 21:48, 29 September 2011

2011-09-29T21:48:41Z

HelenD: /* Diagnosis */

2011-09-20T15:13:24Z

Diagnosis

HelenD at 15:39, 9 September 2011

2011-09-09T15:39:48Z

Bara: /* References */

2011-08-12T16:25:38Z

References

Bara at 23:13, 5 July 2011

2011-07-05T23:13:41Z

Bara at 23:10, 5 July 2011

2011-07-05T23:10:17Z

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 {{Podcasts
 |link = http://media.bloomsburymediacloud.org/podcasts/wikivet-english/inclusion-body-rhinitis
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 |date = 09 September 2011}}
 [[Category:CABI Expert Review Completed]][[Category:CABI AHPC Pages]]

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-[[Category:CABI Expert Review Completed]]
+[[Category:CABI Expert Review Completed]][[Category:CABI AHPC Pages]]
 [[Category:Pig Viruses]]
 [[Category:Respiratory Diseases - Pig]]
 [[Category:Reproductive Diseases - Pig]]

← Older revision		Revision as of 17:27, 22 December 2011
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		+	{{Podcasts
		+	\|link = http://media.bloomsburymediacloud.org/podcasts/wikivet-english/inclusion-body-rhinitis
		+	}}
	Also Known As: '''''IBR — Cytomegalic Inclusion Disease'''''		Also Known As: '''''IBR — Cytomegalic Inclusion Disease'''''

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-[[Cstegory:CABI Expert Review Completed]]
+[[Category:CABI Expert Review Completed]]
 [[Category:Pig Viruses]]
 [[Category:Respiratory Diseases - Pig]]
 [[Category:Reproductive Diseases - Pig]]

@@ Line 37: / Line 37: @@
 '''Antigen''' can be detected serologically by [[FAT|'''fluorescent antibody test (FAT)]].'''
-'''Antibody''' can be detected by '''Indirect Fluorescent Antibody Test (IFAT) and ELISA.'''
+'''Antibody''' can be detected by '''Indirect Fluorescent Antibody Test (IFAT) and [[ELISA testing|ELISA]].'''
 '''PCR''' tests for PCMV have now also been developed and are very sensitive.
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 <br><br>
-This article was expert reviewed by [http://www.rvc.ac.uk/Staff/mnevel.cfm Dr Mandy Nevel] on 09/09/11.
+{{Mandy Nevel
 [[Category:Pig Viruses]]
 [[Category:Respiratory Diseases - Pig]]
 [[Category:Reproductive Diseases - Pig]]

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 '''PCR''' tests for PCMV have now also been developed and are very sensitive.
-On '''post-mortem''', petechiation of the heart, kidneys, intestine, lungs, lymph nodes and meninges is seen in neonatal and foetal pigs. Pulmonary congestion is marked and the bronchial and mediastinal lymph nodes are dramatically enlarged. Ventral aspects of lung lobes are often '''discoloured purple'''. The nasal mucosa is congested with a mucoid exudates.
+On '''post-mortem''', petechiation of the heart, kidneys, intestine, lungs, lymph nodes and meninges is seen in neonatal and foetal pigs. Pulmonary congestion is marked and the bronchial and mediastinal lymph nodes are dramatically enlarged. Ventral aspects of lung lobes are often '''discoloured purple'''. The nasal mucosa is congested with a mucoid exudate.
 Histologically, large '''basophilic intranuclear inclusion bodies are present in the mucosal epithelial cells''' of the turbinates, salivary glands and kidney tissues.

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 PCMV may pose a risk to humans through '''transplanted organs''' and this is currently being researched. It is not currently considered a zoonosis due to its host range being highly restricted to only the pig.
-This disease is '''notifiable''' to the World Organisation for Animal Health [http://www.oie.int/ (OIE)].
+==Epidemiology==
 '''Global'''. No country has established freedom from or eradication of disease. Prevalence of infected herds and infected pigs within a herd is very high albeit with a low incidence of clinical disease.
@@ Line 38: / Line 36: @@
 '''Antigen''' can be detected serologically by [[FAT|'''fluorescent antibody test (FAT)]].'''
 '''Antibody''' can be detected by '''Indirect Fluorescent Antibody Test (IFAT).'''
 '''PCR''' tests for PCMV have now also been developed and are very sensitive.
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 Histologically, large '''basophilic intranuclear inclusion bodies are present in the mucosal epithelial cells''' of the turbinates, salivary glands and kidney tissues.
 Electron microscopy can also be used for the same purpose.
 ==Treatment==
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 |date =16 June 2011
 }}
-<br><br><br>
+<br><br>
 [[Category:CABI Expert Review]]
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 [[Category:Respiratory Diseases - Pig]]
 [[Category:Reproductive Diseases - Pig]]

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 ==References==
 <references/>
-Animal Health & Production Compendium, '''Inclusion Body Rhinitis datasheet''', accessed 16/06/2011 @ http://www.cabi.org/ahpc/
+{{CABI source
+|datasheet = [http://www.cabi.org/ahpc/?compid=3&dsid=79245&loadmodule=datasheet&page=2144&site=160 inclusion body rhinitis] and [http://www.cabi.org/ahpc/Default.aspx?site=160&page=2144&LoadModule=datasheet&CompID=3&dsID=62346 suid herpesvirus 2]
 {{review}}

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-Also Known As – '''''Inclusion Body Rhinitis – Atrophic Rhinitis – IBR – Cytomegalic Inclusion Disease'''''
+Also Known As: '''''IBR — Cytomegalic Inclusion Disease'''''
-Caused By – ''Suid Herpesvirus 2 – SHV-2 – Inclusion Body Rhinitis Virus – Pig Cytomegalovirus – IBRV - PCMV''
+Caused By: '''''Porcine Cytomegalovirus — Suid Herpesvirus 2 — SHV-2 — Inclusion Body Rhinitis Virus — Pig Cytomegalovirus — IBRV — PCMV''
 ==Introduction==
-[[File:Cytomegalovirus infection.jpg|thumb|200px|right|Cytomegalovirus infection histology - note basophilic nuclear inclusino bodies and peri-nuclear halo. Wikimedia Commons]]
+[[File:Cytomegalovirus infection.jpg|thumb|200px|right|Cytomegalovirus infection histology - note basophilic nuclear inclusion bodies and peri-nuclear halo. Wikimedia Commons]]
-Porcine Cytomegalovirus is a '''[[Herpesviridae | herpesvirus]]''' causing '''Inclusion Body Rhinitis''' in pigs.
+Porcine Cytomegalovirus is a '''[[Herpesviridae |herpesvirus]]''' causing '''Inclusion Body Rhinitis''' in pigs.
 PCMV may pose a risk to humans through '''transplanted organs''' and this is currently being researched. It is not currently considered a zoonosis due to its host range being highly restricted to only the pig.
-This disease is '''notifiable''' to the World Organisation for Animal Health [http://www.oie.int/ (OIE)]
+This disease is '''notifiable''' to the World Organisation for Animal Health [http://www.oie.int/ (OIE)].
 ==Distribution==
-'''Global'''. No country has established freedom from or eradication of disease.
+'''Global'''. No country has established freedom from or eradication of disease. Prevalence of infected herds and infected pigs within a herd is very high albeit with a low incidence of clinical disease.
 PCMV can cross the placenta facilitating '''vertical transmission. Horizontal transmission''' between infected pigs is also important.
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 ==Clinical Signs==
-'''Rhinitis – Snuffling, sneezing, coughing, production of purulent/catarrhal discharge, increased lacrimation, conjunctivititis, ocular discharge, epistaxis, dyspnoea.'''
+Respiratory signs:
+<br>'''Rhinitis is most common, causing snuffling, sneezing, coughing, production of purulent/catarrhal discharge, increased lacrimation, conjunctivitis, ocular discharge, epistaxis, dyspnoea.'''
-Anorexia, anaemia,  lethargy, pyrexia and sudden death.
+<br>'''Pneumonia''' may occur.
-'''Pneumonia''' may occur.
+Anorexia, anaemia,  lethargy, pyrexia and sudden death may all be noted.
 '''Reproductive failure''' caused by PCMV is characterised by '''abortion, mummified piglets and birth of stillborn''', weak or stunted pigs. Ulcers and erosions may form on the external genitalia. Sows may develop agalactia.
@@ Line 39: / Line 37: @@
 '''Black discolouration around the eyes''' due to conjunctival exudate is also suggestive.
-'''Antigen''' can be detected serologically by '''Fluorescent Antibody Test (FAT).'''
+'''Antigen''' can be detected serologically by [[FAT|'''fluorescent antibody test (FAT)]].'''
 '''Antibody''' can be detected by '''Indirect Fluorescent Antibody Test (IFAT).'''
@@ Line 67: / Line 65: @@
 Animal Health & Production Compendium, '''Inclusion Body Rhinitis datasheet''', accessed 16/06/2011 @ http://www.cabi.org/ahpc/
-[[Category:To Do - CABI review]]