Ischaemia - Revision history

Bara at 16:45, 15 October 2013

2013-10-15T16:45:33Z

Bara at 15:04, 14 February 2011

2011-02-14T15:04:33Z

Bara: Created page with " * Ischaemia is the failure or reduction of arterial blood supply to an organ or tissue. ===Causes=== * Arteriospasm Arterial trauma Ergotism ** Other drug effects * Co..."

2011-02-14T15:00:12Z

Created page with " * Ischaemia is the failure or reduction of arterial blood supply to an organ or tissue. ===Causes=== * Arteriospasm ** Arterial trauma ** Ergotism ** Other drug effects * Co..."

New page

* Ischaemia is the failure or reduction of arterial blood supply to an organ or tissue.

===Causes===

* Arteriospasm
** Arterial trauma
** Ergotism
** Other drug effects
* Compression of arteries/ arterioles
** Ligatures
** Tourniquets
* Thromboembolism
** Vascular impaction by embolic fragments

===Sequelae===

* Several factors determine the extent and consequences of arterial obstruction.
*# Degree of occlusion
*#* May be partial or complete.
*# Rapidity of occlusion
*#* May be sudden or gradual.
*# Presence and extent of a collateral circulation, such as
*#* Anastomoses
*#* Whether end areterioles are functional or actual.
*#* Efficient alternative arterial supplies.
*# Vulnerability of tissues/ cells to ischemia.
*#* For example, their oxygen dependency and metabolic rate.
*#** E.g. neurones and cardiac myocytes are much more susceptible than fibrous tissue.

* There are two possible scenarios in ischeamia, each with their own sequelae.
*# '''Complete, sudden failure of blood supply'''
*#* Unless there is a good alternative collateral supply, this results in necrosis of tissue.
*#** Collateral supplies may be inadequate to compensate if the blockage is severe.
*#* This focal type of lesion is known as [[Ischaemia and Infarction - Pathology#Infarction|'''infarction''']].
*# '''Incomplete, gradual failure of blood supply'''
*#* Results in “accommodation”.
*#** Manifests as atrophy, sometimes with fibrosis, following cellular hypoxia.
*#*** Minimal fibrosis occurs if collateral/ alternative supplies are good.

[[Category:Circulatory Disorders - Pathology]]

← Older revision		Revision as of 16:45, 15 October 2013
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	[[Category:Circulatory Disorders - Pathology]]		[[Category:Circulatory Disorders - Pathology]]
		+	[[Category:Cardiology Section]]

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 * Ischaemia is the failure or reduction of arterial blood supply to an organ or tissue.
@@ Line 33: / Line 32: @@
 *#* Unless there is a good alternative collateral supply, this results in necrosis of tissue.
 *#** Collateral supplies may be inadequate to compensate if the blockage is severe.
-*#* This focal type of lesion is known as [[Ischaemia and Infarction - Pathology#Infarction|'''infarction''']].
+*#* This focal type of lesion is known as [[Infarction|'''infarction''']].
 *# '''Incomplete, gradual failure of blood supply'''
 *#* Results in “accommodation”.

Ischaemia - Revision history

Bara at 16:45, 15 October 2013

Bara at 15:04, 14 February 2011

Bara: Created page with " * Ischaemia is the failure or reduction of arterial blood supply to an organ or tissue. ===Causes=== * Arteriospasm ** Arterial trauma ** Ergotism ** Other drug effects * Co..."

Bara: Created page with " * Ischaemia is the failure or reduction of arterial blood supply to an organ or tissue. ===Causes=== * Arteriospasm Arterial trauma Ergotism ** Other drug effects * Co..."