Leukopoiesis - Revision history

Fiorecastro at 16:04, 11 April 2022

2022-04-11T16:04:02Z

Fiorecastro at 13:05, 16 March 2022

2022-03-16T13:05:11Z

JoeWright at 08:54, 16 March 2022

2022-03-16T08:54:39Z

Fiorecastro at 15:33, 23 February 2022

2022-02-23T15:33:08Z

Fiorecastro at 17:38, 21 February 2022

2022-02-21T17:38:54Z

Fiorecastro: /* Granulopoiesis */

2022-02-14T18:43:11Z

Granulopoiesis

Rjfrancisrvc: /* Lymphopoiesis */

2012-05-28T11:23:42Z

Lymphopoiesis

Rjfrancisrvc: /* Eosinophils */

2012-05-28T11:22:35Z

Eosinophils

Rjfrancisrvc: /* Basophils */

2012-05-28T11:22:22Z

Basophils

Rjfrancisrvc: /* Neutrophils */

2012-05-28T11:22:01Z

Neutrophils

@@ Line 8: / Line 8: @@
 All granulocytes develop from the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] cells.
 ===Summary of pathways===
 {| cellpadding="10" cellspacing="0" border="1" align="left"
+|
@@ Line 17: / Line 15: @@
 !Basophil
 !Eosinophil
-|rowspan="10"|<p>[[Image:LH_Developing_granulocytes_Histology.jpg|200px|Developing granulocytes]]</p><sup>©RVC 2008</sup>
+| rowspan="10" |<p>[[Image:LH_Developing_granulocytes_Histology.jpg|200px|Developing granulocytes]]</p><sup>©RVC 2008</sup>
 |-
 !Stem cell
-|colspan="4"|CFU-GEMM
+| colspan="4" |CFU-GEMM
 |-
 !CFU
@@ Line 31: / Line 29: @@
 |<p>GM-CSF</p><p>IL-3</p><p>M-CSF</p>
 |<p>GM-CSF</p><p>IL-3</p><p>G-CSF</p>
-|valign="top"|<p>GM-CSF</p><p>IL-3</p>
+| valign="top" |<p>GM-CSF</p><p>IL-3</p>
 |<p>GM-CSF</p><p>IL-3</p><p>IL-5</p>
 |-
-!Rowspan="6"|Stages
+! rowspan="6" |Stages
 |Monoblast
-|colspan="3"|Myelocyte
+| colspan="3" |Myelocyte
 |-
 |Promonocyte
-|colspan="3"|Promyelocyte
+| colspan="3" |Promyelocyte
 |-
-|rowspan="4"|Monocyte
+| rowspan="4" |Monocyte
 |Neutrophilic Myelocyte
 |Basophilic Myelocyte
@@ Line 47: / Line 45: @@
 |-
 |Neutrophilic Metamyelocyte
-|rowspan="2"|Basophilic Metamyelocyte
+| rowspan="2" |Basophilic Metamyelocyte
-|rowspan="2"|Eosinophilic Metamyelocyte
+| rowspan="2" |Eosinophilic Metamyelocyte
 |-
 |Band Cell
@@ Line 56: / Line 54: @@
 |Eosinophil
 |}
 <Br clear="left">
@@ Line 160: / Line 157: @@
 <p>'''Note:'''
 *Between the 'pre-[type] cell' stage and the final mature all the lymphocytes are referred to as 'immature [type] cells'.
-* T cell differentiation into helper, cytotoxic and T cells with regulator functions is induced by IL-10 & TNF-γ</p>
+* T cell differentiation into helper, cytotoxic and T cells with regulator functions is induced by IL-10 & TNF-γ
 [[Category:Haematopoiesis]]

@@ Line 162: / Line 162: @@
 * T cell differentiation into helper, cytotoxic and T cells with regulator functions is induced by IL-10 & TNF-γ</p>
 [[File:NationWide Logo.jpeg|right|link=https://www.nwlabs.co.uk/|alt=NationWide Logo|240x240px|In Partnership with NationWide Laboratories|frameless|thumb|]]
 [[Category:Haematopoiesis]]

@@ Line 161: / Line 161: @@
 *Between the 'pre-[type] cell' stage and the final mature all the lymphocytes are referred to as 'immature [type] cells'.
 * T cell differentiation into helper, cytotoxic and T cells with regulator functions is induced by IL-10 & TNF-γ</p>
 [[Category:Haematopoiesis]]

@@ Line 8: / Line 8: @@
 All granulocytes develop from the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] cells.
-A left shift is seen when immature granulocytes are released due to increased tissue demands. These immature cells are predominantly band neutrophils although metamyelocytes and occasionally myelocytes may be seen. Reference: Nation Wide
+A left shift is seen when immature granulocytes are released due to increased tissue demands. These immature cells are predominantly band neutrophils although metamyelocytes and occasionally myelocytes may be seen. Reference: [[NationWide Laboratories]]
 ===Summary of pathways===
 <div style="text-align: center;">

@@ Line 8: / Line 8: @@
 All granulocytes develop from the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] cells.
-A left shift is seen when immature granulocytes are released due to increased tissue demands. These immature cells are predominantly band neutrophils although metamyelocytes and occasionally myelocytes may be seen. (NW)
+A left shift is seen when immature granulocytes are released due to increased tissue demands. These immature cells are predominantly band neutrophils although metamyelocytes and occasionally myelocytes may be seen. Reference: Nation Wide
 ===Summary of pathways===
 <div style="text-align: center;">

@@ Line 130: / Line 130: @@
 |colspan="4"|CFU-L
 |-align="center"
-|style="background-color:#ffffcc"|<sup>▼Il-7 & Il-11</sup>
+|style="background-color:#ffffcc"|<sup>▼IL-7 & IL-11</sup>
-|colspan="3" style="background-color:#e6e6fa"|<sup>▼Il-7 & SCF</sup>
+|colspan="3" style="background-color:#e6e6fa"|<sup>▼IL-7 & SCF</sup>
 |-align="center"
 |style="background-color:#ffffcc"|B lymphoid cell progenitor
 |colspan="3" style="background-color:#e6e6fa"|T lymphoid cell progenitor
 |-align="center"
-|style="background-color:#ffffcc"|<sup>▼Il-3 & Il-7</sup>
+|style="background-color:#ffffcc"|<sup>▼IL-3 & IL-7</sup>
-|style="background-color:#e6e6fa"|<sup>▼Il-7</sup>
+|style="background-color:#e6e6fa"|<sup>▼IL-7</sup>
-|style="background-color:#e6e6fa"|<sup>▼Il-2, IL-12 & Il-18</sup>
+|style="background-color:#e6e6fa"|<sup>▼IL-2, IL-12 & IL-18</sup>
-|style="background-color:#e6e6fa"|<sup>▼Il-3, Il-6, GM-CSF & SCF</sup>
+|style="background-color:#e6e6fa"|<sup>▼IL-3, IL-6, GM-CSF & SCF</sup>
 |-align="center"
 |style="background-color:#ffffcc"|Pre-B cell
@@ Line 158: / Line 158: @@
 <p>'''Note:'''
 *Between the 'pre-[type] cell' stage and the final mature all the lymphocytes are referred to as 'immature [type] cells'.
-* T cell differentiation into helper, cytotoxic and T cells with regulator functions is induced by Il-10 & TNF-γ</p>
+* T cell differentiation into helper, cytotoxic and T cells with regulator functions is induced by IL-10 & TNF-γ</p>
 [[Category:Haematopoiesis]]

@@ Line 92: / Line 92: @@
 ==Eosinophils==
-Under the stimulation of GM-CSF, Il-3 and Il-5 the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] differentiates into the [[Haematopoiesis - Overview#Colony Forming Units|CFU-Eo]].
+Under the stimulation of GM-CSF, IL-3 and IL-5 the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] differentiates into the [[Haematopoiesis - Overview#Colony Forming Units|CFU-Eo]].
 ===Stages:===
 ====Myeloblast & Promyelocyte====

@@ Line 79: / Line 79: @@
 ==Basophils==
-Under the stimulation of GM-CSF and Il-3, the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] differentiates into [[Haematopoiesis - Overview#Colony Forming Units|CFU-Ba]].
+Under the stimulation of GM-CSF and IL-3, the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] differentiates into [[Haematopoiesis - Overview#Colony Forming Units|CFU-Ba]].
 ===Stages:===
 ====Myeloblast & Promyelocyte====

@@ Line 58: / Line 58: @@
 ==Neutrophils==
-Under the stimulation of [[Cytokines|cytokines]] GM-CSF, G-CSF and Il-3 the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] differentiates into the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GM]], the common precursor for both neutrophils and monocytes. This then further differentiates into [[Haematopoiesis - Overview#Colony Forming Units|CFU-G]].
+Under the stimulation of [[Cytokines|cytokines]] GM-CSF, G-CSF and IL-3 the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] differentiates into the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GM]], the common precursor for both neutrophils and monocytes. This then further differentiates into [[Haematopoiesis - Overview#Colony Forming Units|CFU-G]].
 ===Stages:===
 ====Myeloblast====