Liver Pigmentation - Revision history

Bara at 23:09, 25 July 2011

2011-07-25T23:09:40Z

Bara at 22:06, 25 July 2011

2011-07-25T22:06:11Z

Bara at 13:40, 20 April 2011

2011-04-20T13:40:51Z

Kthompson at 15:43, 30 March 2011

2011-03-30T15:43:15Z

Kthompson at 15:41, 30 March 2011

2011-03-30T15:41:51Z

Bara at 18:39, 15 February 2011

2011-02-15T18:39:59Z

Eca02csb: /* Bile */

2010-08-20T18:09:36Z

Bile

Bara at 22:24, 28 June 2010

2010-06-28T22:24:40Z

Bara: moved Liver Pigmentation - Pathology to Liver Pigmentation

2010-06-07T12:21:18Z

moved Liver Pigmentation - Pathology to Liver Pigmentation

Bara at 12:21, 7 June 2010

2010-06-07T12:21:12Z

@@ Line 36: / Line 36: @@
 {{review}}
 [[Category:Liver_-_Degenerative Pathology]]
-[[Category:Expert_Review - Pathology]]
+[[Category:Nicola Parry reviewing]]

@@ Line 20: / Line 20: @@
 Bile can be stained with Fouchet stain - and appears green. Bile pigmentation is especially prominent in obstructive [[jaundice]]. Underlying causes must be addressed for treatment of this condition.
-==Test yourself with the Liver Pathology Flashcards==
+{{Learning
+|flashcards = [[Liver_Flashcards_-_Pathology|Liver Pathology Flashcards]]
-[[Liver_Flashcards_-_Pathology|Liver Pathology Flashcards]]
+}}
 == References ==

@@ Line 1: / Line 1: @@
 Various substances and conditions can cause pigmentation of the liver.
 ==Congenital melanosis==
 Can occur in calves and lambs at birth. It is not related to clinical disease. Black discolouration occurs in the capsule and stroma of the [[Liver - Anatomy & Physiology|liver]] and these are an abnormal accumulation of melanin pigments.
 ==Haemosiderin==
-Acuumulation of this pigment occurs in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage. The pigment is found within the Kupfer cells (macrophages of the liver) and this can be visualised using Perl's Prussian Blue stain.
+Accumulation of this pigment occurs in chronic passive congestion and surrounding areas where there has been prior [[Liver Necrosis|necrosis]] and haemorrhage. The pigment is found within the Kupfer cells (macrophages of the liver) and can be visualised using Perl's Prussian Blue stain.
 <br>
 ==Lipofuscin==
 Is a pigment of cellular ageing (it is also names the 'senility pigment') and is insoluble and golden brown in colour.
 <br>
-It occurs within heptatocytes and can be identified using Schmorl's stain where the pigment will appear dark blue. It is commonly seen in hepatocytes near to the centrilobular vein in older cats and is of no clinical significance.
+It occurs within hepatocytes and can be identified using Schmorl's stain where the pigment will appear dark blue. It is commonly seen in hepatocytes near to the centrilobular vein in older cats and is of no clinical significance.
 <br>
-==Bile==
+==Test yourself with the Liver Pathology Flashcards==
-<br>
+[[Liver_Flashcards_-_Pathology|Liver Pathology Flashcards]]
 == References ==
-Blood, D.C. and Studdert, V. P. (1999) Saunders Comprehensive Veterinary Dictionary (2nd Edition), Elsevier Science.
+Blood, D.C. and Studdert, V. P. (1999) '''Saunders Comprehensive Veterinary Dictionary''' (2nd Edition),'' Elsevier Science.''
 <br>
-Ettinger, S.J, Feldman, E.C. (2005) Textbook of Veterinary Internal Medicine (6th edition, volume 2), W.B. Saunders Company.
+Ettinger, S.J, Feldman, E.C. (2005) '''Textbook of Veterinary Internal Medicine '''(6th edition, volume 2),'' W.B. Saunders Company.''
 <br>
-Fossum, T. W. et. al. (2007) Small Animal Surgery (Third Edition), Mosby Elsevier.
+Fossum, T. W. et. al. (2007) '''Small Animal Surgery '''(Third Edition), ''Mosby Elsevier.''
 <br>
-Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition), Mosby Elsevier.
+Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine '''(Fourth Edition), ''Mosby Elsevier. ''
 [[Category:Liver_-_Degenerative Pathology]]
-[[Category:To_Do_-_Review]]
+[[Category:Expert_Review - Pathology]]

← Older revision		Revision as of 15:43, 30 March 2011
Line 27:		Line 27:

	<br>		<br>
		+
		+	== References ==
		+	Blood, D.C. and Studdert, V. P. (1999) Saunders Comprehensive Veterinary Dictionary (2nd Edition), Elsevier Science.
		+	<br>
		+	Ettinger, S.J, Feldman, E.C. (2005) Textbook of Veterinary Internal Medicine (6th edition, volume 2), W.B. Saunders Company.
		+	<br>
		+	Fossum, T. W. et. al. (2007) Small Animal Surgery (Third Edition), Mosby Elsevier.
		+	<br>
		+	Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition), Mosby Elsevier.

	==Test yourself with the Liver Pathology Flashcards==		==Test yourself with the Liver Pathology Flashcards==

@@ Line 1: / Line 1: @@
-{{review}}
+Various substances and conditions can cause pigmentation of the liver.
 ==Congenital melanosis==
-*in calves and lambs
+Can occur in calves and lambs at birth. It is not related to clinical disease. Black discolouration occurs in the capsule and stroma of the [[Liver - Anatomy & Physiology|liver]] and these are an abnormal accumulation of melanin pigments.
 ==Haemosiderin==
-*in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage
+Acuumulation of this pigment occurs in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage. The pigment is found within the Kupfer cells (macrophages of the liver) and this can be visualised using Perl's Prussian Blue stain.
-*found within the Kuppfer cells
+<br>
-*use Perls' stain
+The condition does not cause clinical signs alone, but is the consequence of haemorrhage so this will cause clinical signs. Deposition of large amounts of haemosiderin may result in liver failure.
 ==Lipofuscin==
-*an insoluble golden brown pigment which occurs within hepatocytes
+Is a pigment of cellular ageing (it is also names the 'senility pigment') and is insoluble and golden brown in colour.
-*use Schmorl's stain - dark blue
+<br>
-*increases with age - called the ''''senility' pigment'''
+It occurs within heptatocytes and can be identified using Schmorl's stain where the pigment will appear dark blue. It is commonly seen in hepatocytes near to the centrilobular vein in older cats and is of no clinical significance.
-*it is commonly seen in hepatocytes near to the centrilobular vein in older cats
-*no clinical significance
+<br>
 ==Bile==
-*especially prominent in obstructive jaundice
+Bile pigment discolours tissues green and therefore is very noticeable at necropsy. Often, intrahepatic bile caniculi are distended with a greenish pigment and are known as 'bile lakes'. Larger foci are seen in long standing cases when the hepatocytes rupture: the discharged bile is then surrounded by macrophages and perhaps giant cells.
-*discolours the tissues green
+<br>
-*intrahepatic bile canaliculi are distended with a greenish pigment - called '''bile plugs'''
+Bile can be stained with Fouchet stain - and appears green.
-*larger foci are seen in long standing cases when the hepatocytes rupture: the discharged bile is then surrounded by macrophages and perhaps giant cells - called '''bile lakes'''
+Bile pigmentation is especially prominent in obstructive jaundice. Underlying causes must be addressed for treatment of this condition.
-*use Fouchet stain - green
 ==Test yourself with the Liver Pathology Flashcards==
@@ Line 30: / Line 33: @@
 [[Category:Liver_-_Degenerative Pathology]]
-[[Category:To_Do_-_Clinical]]
+[[Category:To_Do_-_Review]]

← Older revision		Revision as of 22:24, 28 June 2010
Line 25:		Line 25:
	*use Fouchet stain - green		*use Fouchet stain - green
	[[Category:Liver_-_Pathology]]		[[Category:Liver_-_Pathology]]
		+	[[Category:To_Do_-_Clinical]]

← Older revision	Revision as of 12:21, 7 June 2010
(No difference)