Mammary Hyperplasia - Revision history

Bara at 12:16, 9 August 2012

2012-08-09T12:16:13Z

Bara at 15:28, 8 September 2011

2011-09-08T15:28:39Z

HelenD: /* Treatment */

2011-08-10T10:01:11Z

Treatment

HelenD: Created page with "Also know as: '''''Fibroadenomatous hyperplasia — Fibroepithelial hyperplasia''''' ==Introduction== Mammary hyperplasia is a disorder characterised by '''rapid and dramatic en..."

2011-08-10T09:59:46Z

Created page with "Also know as: '''''Fibroadenomatous hyperplasia — Fibroepithelial hyperplasia''''' ==Introduction== Mammary hyperplasia is a disorder characterised by '''rapid and dramatic en..."

New page

Also know as: '''''Fibroadenomatous hyperplasia — Fibroepithelial hyperplasia'''''

==Introduction==
Mammary hyperplasia is a disorder characterised by '''rapid and dramatic enlargement of multiple mammary glands''' in '''cats'''.

It typically occurs in '''young, cycling females''' but is also occasionally seen in males and spayed females.

It has been related to the high levels of progesterone in pregnancy, but can also occur with exogenous progesterone administration.

It is a benign condition, but must be differentiated from mammary neoplasia.

==Clinical signs==
There is usually '''rapid onset of signs''', usually with enlargement of all the mammary glands and involvement of both epithelial and mesenchymal tissue.

The swelling is generally '''not painful''', although secondary infection of the glands may occur. There may then be pain, erythema and ulceration of the glands.

'''Milk production''' may occur even though most affected cats are not lactating.

==Diagnosis==
The main aim is to differentiate this condition from [[Mammary Neoplasia|mammary neoplasia]].

The rapid and dramatic symmetrical enlargement of the glands is usually diagnostic, however it might be useful to confirm this by performing a '''biopsy and histopathology''' of the mammary tissue.

'''Histologically''', there is marked proliferation of the intralobular duct system. The branching ducts are lined with epithelial cells often three to four layers thick. There is no evidence of stromal invasion of epithelial cells. This is the appearance of '''mammary tissue in early pregnancy''' when it is first coming under the influence of progesterone.

'''Cytology of mammary secretions''' can also be performed and this fluid should be void of any neoplastic cells.

==Treatment==
The source of the progesterone should be withdrawn if possible and the condition will resolve in a few weeks.

'''Unspayed females should be spayed'''. A flank incision may be preferable to avoid the hyperplastic mammary tissue in the midline.

Cats not receiving exogenous progesterone usually have '''remission within a few weeks'''.

Other '''symptomatic treatments''' include:

''Analgesics'': if the cat is in pain

''Mastectomy'': if ulceration of the glands has occurred or if remission is taking time

''Prolactin inhibitor'': it is not licence in cats and has many side effects including vomiting and anorexia.

{{Learning
|flashcards = [[Feline Medicine Q&A 18]]
}}

==References==
Norsworthy, G. (2011) '''The Feline Patient''' ''John Wiley and Sons''

Moulton, J. (1978) '''Tumors in domestic animals''' ''University of California Press''

Arndt, J. '''Feline Mammary Hyperplasia''' ''UC Davis publication''

[[Category:To Do - Helen]]
[[Category:To Do - Review]]

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 Also know as: '''''Fibroadenomatous Hyperplasia — Fibroepithelial Hyperplasia'''''
@@ Line 50: / Line 51: @@
 {{review}}
 [[Category:Dermatological Diseases - Cat]]
 [[Category:Expert Review - Small Animal]]

@@ Line 1: / Line 1: @@
-Also know as: '''''Fibroadenomatous hyperplasia — Fibroepithelial hyperplasia'''''
+Also know as: '''''Fibroadenomatous Hyperplasia — Fibroepithelial Hyperplasia'''''
 ==Introduction==
 Mammary hyperplasia is a disorder characterised by '''rapid and dramatic enlargement of multiple mammary glands''' in '''cats'''.
-It typically occurs in '''young, cycling females''' but is also occasionally seen in males and spayed females.
+It typically occurs in '''young, cycling females''' but is also occasionally seen in males and spayed females. It has been related to the high levels of progesterone in pregnancy, but can also occur with exogenous progesterone administration. It is a benign condition, but must be differentiated from mammary neoplasia.
-It has been related to the high levels of progesterone in pregnancy, but can also occur with exogenous progesterone administration.
+==Clinical Signs==
 There is usually '''rapid onset of signs''', usually with enlargement of all the mammary glands and involvement of both epithelial and mesenchymal tissue. The swelling is generally '''not painful''', although secondary infection of the glands may occur. There may then be pain, erythema and ulceration of the glands.
 '''Milk production''' may occur even though most affected cats are not lactating.
@@ Line 39: / Line 33: @@
 ''Mastectomy'': if ulceration of the glands has occurred or if remission is taking time
-''Prolactin inhibitor'': it is not licenced in cats and has many side effects including vomiting and anorexia.
+''Prolactin inhibitor'': it is not licensed in cats and has many side effects including vomiting and anorexia.
-''Progesterone Receptor Antagonist'': can also be used although it is not licenced and may cause abortion in pregnant queens.
+''Progesterone Receptor Antagonist'': can also be used although it is not licensed and may cause abortion in pregnant queens.
 {{Learning
@@ Line 54: / Line 48: @@
 Arndt, J. '''Feline Mammary Hyperplasia''' ''UC Davis publication''
-[[Category:To Do - Helen]]
-[[Category:To Do - Review]]
+{{review}}