Mice (Laboratory) - Pathology - Revision history

Jrodgers at 07:44, 27 February 2012

2012-02-27T07:44:56Z

2012-02-27T07:44:22Z

Changed "white" to "albino" as these mice have non pigmented eyes.

2011-02-15T15:42:17Z

2010-08-31T10:03:22Z

References

2010-08-27T15:38:15Z

2010-08-27T15:37:53Z

2010-08-27T15:30:32Z

Genetically Engineered Mice

2010-08-27T15:28:51Z

Genetically Engineered Mice

2010-08-27T15:26:53Z

Strain Information

2010-08-27T15:24:15Z

Strain Information

@@ Line 1: / Line 1: @@
 {{review}}
-[[Image:White_mouse.jpg|200px|thumb|right|''Albino Mice''' WikiCommons]]
+[[Image:White_mouse.jpg|200px|thumb|right|''Albino Mice'' WikiCommons]]
 ==Anatomic features==
 The laboratory mouse has several unique characteristics, and there are vast differences in normal anatomy, physiology, and behaviour among different strains of mice, many of which represent abnormalities arising from homozygosity of recessive or mutant traits in inbred mice.

@@ Line 1: / Line 1: @@
 {{review}}
-[[Image:White_mouse.jpg|200px|thumb|right|'''White Mice''' WikiCommons]]
+[[Image:White_mouse.jpg|200px|thumb|right|''Albino Mice''' WikiCommons]]
 ==Anatomic features==
 The laboratory mouse has several unique characteristics, and there are vast differences in normal anatomy, physiology, and behaviour among different strains of mice, many of which represent abnormalities arising from homozygosity of recessive or mutant traits in inbred mice.

@@ Line 1: / Line 1: @@
 {{review}}
-{{toplink
 [[Image:White_mouse.jpg|200px|thumb|right|'''White Mice''' WikiCommons]]
 ==Anatomic features==
@@ Line 51: / Line 46: @@
 *http://jaxmice.jax.org/type/gemm/index.html

← Older revision		Revision as of 10:03, 31 August 2010
Line 49:		Line 49:
	== References==		== References==
	*{{citation\|initiallast = Percy\|initialfirst = D.H\|2last = and Barthold\|2first = S.W\|finallast = \|year = 2007\|title = Pathology of laboratory rodents and rabbits\|pub = Blackwell Publishing. pp. 3-123}}		*{{citation\|initiallast = Percy\|initialfirst = D.H\|2last = and Barthold\|2first = S.W\|finallast = \|year = 2007\|title = Pathology of laboratory rodents and rabbits\|pub = Blackwell Publishing. pp. 3-123}}
		+
		+	*http://jaxmice.jax.org/type/gemm/index.html

@@ Line 6: / Line 6: @@
 |pagetype =Pathology
 }}
-[[Image:White_mouse.jpg|200px|thumb|right|'''White Mouse''' WikiCommons]]
+[[Image:White_mouse.jpg|200px|thumb|right|'''White Mice''' WikiCommons]]
 ==Anatomic features==
 The laboratory mouse has several unique characteristics, and there are vast differences in normal anatomy, physiology, and behaviour among different strains of mice, many of which represent abnormalities arising from homozygosity of recessive or mutant traits in inbred mice.

@@ Line 32: / Line 32: @@
 '''For more information on specific strains and the pathology associated with them, click [[Laboratory mice strain information|here]]
-==[[Genetically Engineered Mice]]==
+==Genetically Engineered Mice==
 ===Terminology===
 Genetically engineered mice have induced mutations, including transgenes, targeted mutations (knockouts or knockins), and retroviral, proviral, or chemically-induced mutations.

@@ Line 33: / Line 33: @@
 ==[[Genetically Engineered Mice]]==
 == References==
 *{{citation|initiallast = Percy|initialfirst = D.H|2last = and Barthold|2first = S.W|finallast = |year = 2007|title = Pathology of laboratory rodents and rabbits|pub = Blackwell Publishing. pp. 3-123}}

@@ Line 26: / Line 26: @@
 '''Melanosis''' occurs in several organs, including the anteroventral meninges of the olfactory bulbs, optic nerves, parathyroid glands, heart valves, and spleens of melanotic mouse strains, such as B6 mice.
-==[[Laboratory mice strain information|Strain Information]]==
+==Strain Information==
 Most laboratory mice have contributions from both Mus musculus musculus and Mus musculus domesticus. There is evidence that smaller contributions also may have come from Mus musculus molossinus and Mus musculus castaneus. Therefore, they should not be referred to by species name, but rather as laboratory mice or by use of a specific strain or stock name. (In addition, some recently developed laboratory mouse strains are derived wholly from other Mus species or other subspecies, such as M. spretus). The laboratory mouse genome, including its retroelements, is a mosaic and an artificial creation, and there is no true "wildtype" laboratory mouse.
 There are over 450 inbred strains that have arisen during the last century but the great majority of biomedical resaerch, including genomic research, is based on a relatively few mouse strains, including C57BL/6, BALB/c, C3H/He, 129, FVB, and outbred Swiss stocks.
 ==[[Genetically Engineered Mice]]==

← Older revision		Revision as of 15:24, 27 August 2010
Line 27:		Line 27:

	==[[Laboratory mice strain information\|Strain Information]]==		==[[Laboratory mice strain information\|Strain Information]]==
		+	Most laboratory mice have contributions from both Mus musculus musculus and Mus musculus domesticus. There is evidence that smaller contributions also may have come from Mus musculus molossinus and Mus musculus castaneus. Therefore, they should not be referred to by species name, but rather as laboratory mice or by use of a specific strain or stock name. (In addition, some recently developed laboratory mouse strains are derived wholly from other Mus species or other subspecies, such as M. spretus). The laboratory mouse genome, including its retroelements, is a mosaic and an artificial creation, and there is no true "wildtype" laboratory mouse.
		+	There are over 450 inbred strains that have arisen during the last century but the great majority of biomedical resaerch, including genomic research, is based on a relatively few mouse strains, including C57BL/6, BALB/c, C3H/He, 129, FVB, and outbred Swiss stocks.

	==[[Genetically Engineered Mice]]==		==[[Genetically Engineered Mice]]==