Porcine Circoviruses - Revision history

Timfee: /* Treatment and Control */

2013-11-01T11:05:43Z

Treatment and Control

Bara at 17:21, 30 July 2012

2012-07-30T17:21:35Z

Bara at 22:28, 16 June 2011

2011-06-16T22:28:18Z

Bara at 15:10, 26 April 2011

2011-04-26T15:10:23Z

Kthompson at 13:53, 19 April 2011

2011-04-19T13:53:19Z

Bara at 18:33, 19 February 2011

2011-02-19T18:33:25Z

Bara: /* Literature Search */

2011-01-17T18:36:52Z

Literature Search

Bara: /* Literature Search */

2011-01-17T18:36:24Z

Literature Search

Bara: /* Literature Search */

2010-11-14T12:24:13Z

Literature Search

Bara at 12:19, 14 November 2010

2010-11-14T12:19:09Z

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 == Treatment and Control ==
-There are currently no vaccines available for this condition. [[Antibiotics]] can be used to treat/prevent any secondary bacterial infections.
+Vaccines are available for control of PMWS. [[Antibiotics]] can be used to treat/prevent any secondary bacterial infections.
 Control measures include good ventilation, bio-security and proper management. Passive antibody can sometimes be used in severe circumstances.

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 Also known as: '''''Post-weaning Multisystemic Wasting Syndrome — PMWS — Porcine Dermatitis and Nephropathy Syndrome — PDNS — PCV '''''
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 {{review}}
 [[Category:Circoviridae]][[Category:Pig Viruses]]
 [[Category:Expert_Review - Farm Animal]]
 [[Category:Respiratory_Viral_Infections]]
 [[Category:Musculoskeletal Diseases - Pig]][[Category:Intestinal Diseases - Pig]][[Category:Respiratory Diseases - Pig]][[Category:Urological Diseases - Pig]]

@@ Line 35: / Line 35: @@
 Control measures include good ventilation, bio-security and proper management. Passive antibody can sometimes be used in severe circumstances.
+{{Learning
-Use these links to find recent scientific publications via CABI Abstracts (log in required unless accessing from a subscribing organisation).
+|full text = [http://www.cabi.org/cabdirect/FullTextPDF/2008/20083075304.pdf ''' Porcine circovirus structure and replication: a minireview.''' Weingartl, H. M.; University of Maribor, Faculty of Agriculture, Maribor, Slovenia, Agricultura (Slovenia), 2002, 1, 1, pp 11-14, 28 ref.]
-<br><br><br>
+}}

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 == Introduction ==
 There are two serotypes of porcine circovirus, which are as follows; PCV1 which is harmless and PCV2 which is virulent. The virulent serotype, PCV2, causes Post-weaning Multisystemic Wasting Syndrome (PMWS) in young pigs and Porcine Dermatitis and Nephropathy Syndrome (PDNS) in older pigs.
 <br>
-PCV2 is the most important widespread porcine virus as it causes detrimental losses to the industry and predisposes to secondary infection, which obviously can therefore result in further losses. It is easily misdiagnosed. Route of transmission is via the faeco-oral route or venereal route. The host often mounts a poor immune response to the condition.
+PCV2 is the most important widespread porcine virus as it causes detrimental losses to the industry and predisposes to secondary infection, which obviously can result in further losses. It is easily misdiagnosed. Route of transmission is via the faeco-oral route or venereal route. The host often mounts a poor immune response to the virus.
 == PMWS ==
-This disease causes enlarged lymph nodes and lymphopenia, as the virus concentrates in germinal centers.
+This disease causes enlarged lymph nodes and [[lymphopenia]], as the virus concentrates in germinal centers.
 === Signalment ===
 Typically strikes '''weaners''' of around 8-12 weeks old.
 === Clinical Signs ===
-Clinical signs include pale skin colour and/ or jaundiced skin, enlarged lymph nodes and kidneys, and unthrifty appearance and lameness. There may also be signs of respiratory disease, such as mild [[Interstitial Pneumonia|interstitial pneumonia]], failure of lungs to collpse on opening the thoracic cavity and also diarrhoea. Some may present as sudden death and mortality rates can reach 40% in an outbreak.
+Clinical signs include pale skin colour and/or jaundiced skin, enlarged lymph nodes and kidneys, and unthrifty appearance and lameness. There may also be signs of respiratory disease, such as mild [[Interstitial Pneumonia|interstitial pneumonia]], failure of lungs to collapse on opening the thoracic cavity and also diarrhoea. Some may present as sudden death and mortality rates can reach 40% in an outbreak.
 === Differential Diagnoses ===
-There are a large range of differentials, particularly [[Classical Swine Fever|Swine Fever]], African Swine Fever, ''Pasteurella'', and colisepticemia
+There are a large range of differentials, particularly [[Classical Swine Fever]], [[African Swine Fever]], ''Pasteurella'', and colisepticemia.
 == PDNS ==
-This condition can follow PMWS or can be seen as a stand alone condition and presents as an immune-mediated '''necrotising vasculitis'''
+This condition can follow PMWS or can be seen as a stand alone condition and presents as an immune-mediated '''necrotising vasculitis'''.
 === Signalment ===
 It is typically seen in growers and finishers.
 === Clinical Signs ===
 Signs can include extensive hemorrhages of kidneys and skin, especially in the scrotal region, accompanied by pyrexia.
 == Diagnosis ==
 Diagnosis of these conditions is based on clinical signs and history and signalment. Definitive diagnosis can be achieved by performing a PCR for the PCv nucleic acid, however some positive animals can show no clinical signs. Differentials such as Classical Swine Fever must be ruled out.
-<br>
+== Treatment and Control ==
 Control measures include good ventilation, bio-security and proper management. Passive antibody can sometimes be used in severe circumstances.
 ==Literature Search==
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 [[Category:Circoviridae]][[Category:Pig Viruses]]
+[[Category:Expert_Review - Farm Animal]]
 [[Category:Respiratory_Viral_Infections]]
 [[Category:Musculoskeletal Diseases - Pig]][[Category:Intestinal Diseases - Pig]][[Category:Respiratory Diseases - Pig]][[Category:Urological Diseases - Pig]]

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-{{unfinished}}
+== Introduction ==
-====Antigenicity====
+<br>
-====Pathogenesis====
+== PMWS ==
-'''PMWS''':
+This disease causes enlarged lymph nodes and lymphopenia, as the virus concentrates in germinal centers.
-====Epidemiology====
+<br>
-====Diagnosis====
+=== Signalment ===
-*Clinical signs
+Typically strikes '''weaners''' of around 8-12 weeks old.
-====Control====
+<br>
-===Postweaning multisystemic wasting syndrome (PMWS)===
+=== Clinical Signs ===
-*Caused by a [[Circoviridae|porcine circovirus]] alone or in combination with [[Parvoviridae|porcine parvovirus]]
+<br>
-*May cause mild [[Interstitial Pneumonia|interstitial pneumonia]], failure of lungs to collpse on opening the thoracic cavity
-*Microscopically: thickening of alveolar wall due to type 2 pneumocyte hyperplasia
+=== Differential Diagnoses ===
 ==Literature Search==
@@ Line 60: / Line 56: @@
-Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
+Use these links to find recent scientific publications via CABI Abstracts (log in required unless accessing from a subscribing organisation).
 <br><br><br>
 [http://www.cabi.org/cabdirect/FullTextPDF/2008/20083075304.pdf ''' Porcine circovirus structure and replication: a minireview.''' Weingartl, H. M.; University of Maribor, Faculty of Agriculture, Maribor, Slovenia, Agricultura (Slovenia), 2002, 1, 1, pp 11-14, 28 ref. - '''Full Test article''']
@@ Line 67: / Line 63: @@
 [[Category:Circoviridae]][[Category:Pig Viruses]]
-[[Category:To_Do_-_Clinical/Viruses]]
+[[Category:To_Do_-_Review]]
 [[Category:Respiratory_Viral_Infections]]
 [[Category:Musculoskeletal Diseases - Pig]][[Category:Intestinal Diseases - Pig]][[Category:Respiratory Diseases - Pig]][[Category:Urological Diseases - Pig]]

← Older revision		Revision as of 12:19, 14 November 2010
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	*Microscopically: thickening of alveolar wall due to type 2 pneumocyte hyperplasia		*Microscopically: thickening of alveolar wall due to type 2 pneumocyte hyperplasia

		+	==Literature Search==
		+	[[File:CABI logo.jpg\|left\|90px]]

		+
		+	Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
		+	<br><br><br>
		+	[http://www.cabi.org/cabdirect/FullTextPDF/2008/20083075304.pdf ''' Porcine circovirus structure and replication: a minireview. Weingartl, H. M.; University of Maribor, Faculty of Agriculture, Maribor, Slovenia, Agricultura (Slovenia), 2002, 1, 1, pp 11-14, 28 ref. - '''Full Test article''']