Seborrhea - Revision history

Bara at 18:19, 18 July 2012

2012-07-18T18:19:20Z

Bara at 22:20, 6 September 2011

2011-09-06T22:20:57Z

HelenD: e

2011-09-02T07:02:44Z

HelenD at 16:47, 1 September 2011

2011-09-01T16:47:16Z

Bara: Created page with " Epidermal growth or differentiation disorder ===Seborrheic disease complex=== Abnormal cornification or function of sebaceous glands *Large amounts of free fatty acids and ..."

2011-02-22T18:24:07Z

Created page with " *Epidermal growth or differentiation disorder ===Seborrheic disease complex=== *Abnormal cornification or function of sebaceous glands *Large amounts of free fatty acids and ..."

New page

*Epidermal growth or differentiation disorder

===Seborrheic disease complex===

*Abnormal cornification or function of sebaceous glands
*Large amounts of free fatty acids and cholesterol
*Decreased amounts of diester waxes in surface lipids
*Bacterial population changes to pathogenic [[:Category:Staphylococcus species|coagulase positive staphylococci]]
*Chronic disease affecting mainly dogs, sometimes cats and horses
*Dry form - white to grey scales
*Greasy form - scaly, excess brown to yellow lipids sticking to skin and hair

===Primary idiopathic seborrhea===
*Abnormal cornification
*Epidermal turnover reduced to about 2/3 of normal
*Microscopically:
**Hyperkeratosis distending follicular ostia causing papillary appearance
**Parakeratosis at edges of follicular ostia
**Congested, oedematous dermal papillae
**Spongiotic epidermis with leukocytes

===Secondary seborrhea===
*Develops secondarily to many types of disease (''e.g.'' [[:Category:Integumentary System - Parasitic Infections|ectoparasites]], [[:Category:Integumentary System - Mycotic Infections|fungal infections]], [[Endocrine effects on the skin - Pathology|endocrine disease]], internal disease or allergy)
*Microscopically:
**Hyperkeratosis and/or parakeratosis of follicles and epidermis
**Lesions relevant to the other disease

[[Category:Integumentary System - Pathology]]

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 ==Introduction==
 Seborrhea is characterised by a '''defect in keratinisation or cornification'''. This results in increased scale formation, a greasy skin and hair coat and often secondary inflammation and infection.
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 {{review}}
 [[Category:Dermatological Diseases - Dog]][[Category:Dermatological Diseases - Cat]][[Category:Dermatological Diseases - Horse]]
 [[Category:Expert Review]]
 [[Category:Integumentary System - Pathology]]

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 Seborrhea is characterised by a '''defect in keratinisation or cornification'''. This results in increased scale formation, a greasy skin and hair coat and often secondary inflammation and infection.
-There are large amounts of free fatty acids and cholesterol and decreased amounts of diester waxes in surface lipids which lead bacterial populations to become pathogenic [[:Category:Staphylococcus species|coagulase positive staphylococci]]
+There are large amounts of free fatty acids and cholesterol and decreased amounts of diester waxes in surface lipids which lead bacterial populations to become pathogenic [[:Category:Staphylococcus species|coagulase positive staphylococci]].
 It is a '''chronic disease''' affecting mainly dogs, but also sometimes cats and horses.
-==Primary idiopathic seborrhea==
+==Primary Idiopathic Seborrhea==
 This is a common '''inherited skin disorder''' seen most frequently in '''Cocker Spaniels'''. Basal epidermal cells in affected dogs undergo accelerated cellular proliferation and turnover.
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 Abnormal keratinisation begins from a '''very early age''' and tend to worsen with time.
-==Secondary seborrhea==
+==Secondary Seborrhea==
 Secondary seborrhea occurs due to an '''underlying disease''' predisposing to excessive scale, crusting and oiliness.
 The most common causes are endocrinopathies and allergies, but other diagnoses should be considered.
-For animals '''under the age of 1''': demodecosis, cheyletiellosis, scabies, nutritional deficiencies, icthyosis, epidermal dysplasia, food hypersensitivity and atopy.
+For animals '''under the age of one''': [[demodecosis]], [[cheyletiellosis]], [[scabies]], nutritional deficiencies, icthyosis, epidermal dysplasia, food hypersensitivity and [[Atopic Dermatitis|atopy]].
-In animals up to 5, '''allergy''' is the most common cause of seborrhea.
+In animals up to five years old, '''allergy''' is the most common cause of seborrhea.
 In animals over the age of 5 an '''endocrinopathy''' or neoplasia become more likely.
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 Sulfur, salicylic acid and benzoxyl peroxide should be used in more severe cases needing agents with keratinolytic, keratinoplastic and antimicrobial effects.
-In most cases the '''prognosis is good''', but treatment is usually complex and involves alot of input from both the vet and the owner.
+In most cases the '''prognosis is good''', but treatment is usually complex and involves a lot of input from both the vet and the owner.
 {{Learning
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 Merck and Co (2008) '''The Merck Veterinary Manual''' ''Merial''
 [[Category:Integumentary System - Pathology]]