Sendai Virus - Revision history

Bara at 18:20, 18 July 2012

2012-07-18T18:20:42Z

Bara at 21:54, 20 April 2011

2011-04-20T21:54:22Z

Kthompson at 18:34, 24 March 2011

2011-03-24T18:34:52Z

Bara at 16:35, 13 August 2010

2010-08-13T16:35:35Z

Bara: Text replace - "Category:To_Do_-_Viruses" to "Category:To_Do_-_Clinical/Viruses"

2010-07-30T12:25:50Z

Text replace - "Category:To_Do_-_Viruses" to "Category:To_Do_-_Clinical/Viruses"

Bara at 22:46, 26 June 2010

2010-06-26T22:46:25Z

A.allison: Text replace - 'Lymphocytes - WikiBlood' to 'Lymphocytes'

2010-06-12T12:37:53Z

Text replace - 'Lymphocytes - WikiBlood' to 'Lymphocytes'

Bara: Created page with '===Murine Parainfluenza - 1 (Sendai Virus)=== Endemic in many '''mouse''' colonies Most mice show no symptoms due to maternal antibodies *But minor respiratory lesions may …'

2010-05-22T11:21:18Z

Created page with '===Murine Parainfluenza - 1 (Sendai Virus)=== *Endemic in many '''mouse''' colonies *Most mice show no symptoms due to maternal antibodies *But minor respiratory lesions may …'

New page

===Murine Parainfluenza - 1 ([[Sendai Virus]])===
*Endemic in many '''mouse''' colonies
*Most mice show no symptoms due to maternal antibodies
*But minor respiratory lesions may invalidate carcinogenic or toxicological studies
*Immunological studies also confused due to virus activating [[Lymphocytes - WikiBlood#Natural Killer (NK) Cells|NK cells]] via high circulating [[Innate Immune System - WikiBlood#Interferons|IF]] 3-4 days post-infection
*Control achieved by:
**Purchasing '''specific pathogen free (SPF)''' mice
**Kill whole colony in an outbreak -> disinfection -> formalin fumigation
[[Category:Paramyxovirinae]][[Category:Rodents]]

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 Also known as: '''''Murine Parainfluenza - 1'''''
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 {{review}}
 [[Category:Paramyxovirinae]] [[Category:Rodents]] [[Category:Expert_Review]]

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 Also known as: '''''Murine Parainfluenza - 1'''''
 == Introduction ==
-Sendai virus is of the family paramyxoviridae. It is endemic in '''mouse''' colonies worldwide, but rarely shows as a clinical disease as maternal anitbody is usually high so the disease rarely has clinical effects.
+Sendai virus is of the family [[Paramyxovirinae|Paramyxoviridae]]. It is endemic in '''mouse''' colonies worldwide, but rarely shows as a clinical disease as maternal antibody is usually high so the disease rarely has any clinical effects.
 == Clinical Signs ==
-There may be mild clinical signs related to the respiratory tract such as nasal discharge or coughing and increased respiratory rate. The animal may be inappentant and lethargic for a short period.
+There may be mild clinical signs related to the respiratory tract such as nasal discharge or coughing and increased respiratory rate. The animal may be inappetant and lethargic for a short period.
 == Diagnosis ==
 Virus isolation is diagnostic.
 == Control ==
-Control is achived by purchasing '''specific pathogen free (SPF)''' mice, which have been screened serologically as having not been exposed to many viruses and bacteria. This is obviously only avaliable in large scale laboratories.
+Control is achieved by purchasing '''specific pathogen free (SPF)''' mice, which have been screened serologically as having not been exposed to many viruses and bacteria. This is obviously only available in large scale laboratories.
-In the cases of an outbreak, the whole colony should be destroyed and disinfection&nbsp;and formalin fumigation should take place.
+In the cases of an outbreak, the whole colony should be destroyed and disinfection and formalin fumigation should take place.
-== References ==
+Bridger, J and Russell, P (2007) '''Virology Study Guide,''''' Royal Veterinary College ''
-Blood, D.C. and Studdert, V. P. (1999) Saunders Comprehensive Veterinary Dictionary (2nd Edition), Elsevier Science <br>Bridger, J and Russell, P (2007) Virology Study Guide, Royal Veterinary College <br>Paterson, S (2006) Skin Diseases of Exotic Pets, Blackwell Publishing <br>Roberts, W.A. and Carter, G.A.(1976) Essentials of Veterinary Virology, Michigan State University Press, East Lansing, Michigan
+Paterson, S (2006) '''Skin Diseases of Exotic Pets,''''' Blackwell Publishing ''
-[[Category:Paramyxovirinae]] [[Category:Rodents]] [[Category:To_Do_-_Review]]
+{{review}}

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 **Kill whole colony in an outbreak -> disinfection -> formalin fumigation
 [[Category:Paramyxovirinae]][[Category:Rodents]]
-[[Category:To_Do_-_Viruses]]
+[[Category:To_Do_-_Clinical/Viruses]]

← Older revision		Revision as of 22:46, 26 June 2010
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	**Kill whole colony in an outbreak -> disinfection -> formalin fumigation		**Kill whole colony in an outbreak -> disinfection -> formalin fumigation
	[[Category:Paramyxovirinae]][[Category:Rodents]]		[[Category:Paramyxovirinae]][[Category:Rodents]]
		+	[[Category:To_Do_-_Viruses]]

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 *Most mice show no symptoms due to maternal antibodies
 *But minor respiratory lesions may invalidate carcinogenic or toxicological studies
-*Immunological studies also confused due to virus activating [[Lymphocytes#Natural Killer (NK) Cells|NK cells]] via high circulating [[Innate Immune System - WikiBlood#Interferons|IF]] 3-4 days post-infection
+*Immunological studies also confused due to virus activating [[Natural Killer cells|NK cells]] via high circulating [[Interferons|IF]] 3-4 days post-infection
 *Control achieved by:
 **Purchasing '''specific pathogen free (SPF)''' mice