Upper Alimentary Tract Carcinoma Complex - Revision history

Bara: Text replace - "[[Eructation - Anatomy & Physiology" to "[[Eructation"

2013-02-08T09:22:56Z

Text replace - "[[Eructation - Anatomy & Physiology" to "[[Eructation"

Bara at 12:17, 4 May 2011

2011-05-04T12:17:40Z

Bara at 13:20, 17 January 2011

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Bara at 13:20, 17 January 2011

2011-01-17T13:20:11Z

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2010-09-06T13:44:58Z

Text replace - "[[The Rumen - Anatomy & Physiology|" to "[[Rumen - Anatomy & Physiology|"

Bara: Text replace - "[[Oral Cavity - Oropharynx - Anatomy & Physiology|" to "[[Oropharynx - Anatomy & Physiology|"

2010-09-05T15:22:06Z

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Bara: Text replace - "[[Alimentary - Anatomy & Physiology|" to "[[Alimentary System Overview - Anatomy & Physiology|"

2010-08-31T15:28:40Z

Text replace - "[[Alimentary - Anatomy & Physiology|" to "[[Alimentary System Overview - Anatomy & Physiology|"

Bara at 11:57, 1 July 2010

2010-07-01T11:57:49Z

Bara at 22:27, 28 June 2010

2010-06-28T22:27:23Z

Bara: Created page with '=====Aetiology===== The most important oesophageal neoplasm is squamous cell carcinoma in the cow. This tumou…'

2010-05-28T11:32:08Z

Created page with '=====Aetiology===== *The most important oesophageal neoplasm is squamous cell carcinoma in the cow. *This tumou…'

New page

=====Aetiology=====
*The most important [[Oesophagus - Anatomy & Physiology|oesophageal]] neoplasm is [[Squamous Cell Carcinoma|squamous cell carcinoma]] in the cow.
*This tumour is seen as part of a more general syndrome of upper alimentary tract neoplasia in adult cattle grazing rough pasture on which the '''bracken fern''' (Pteridium aquilinum) is present.
*The syndrome is seen in various part of the world including the Western Highlands of Scotland, Brazil and Kenya.
*In affected animals, squamous carcinomas may be present in the [[Oral Cavity - Oropharynx - Anatomy & Physiology|oropharynx]], [[Oesophagus - Anatomy & Physiology|oesophagus]] and [[The Rumen - Anatomy & Physiology|rumen]] and there may also be [[intestinal adenocarcinomas]] and bladder tumours, or the condition known as [[enzootic bovine haematuria]].

=====Pathogenesis=====
*Experimentally, the feeding of bracken to laboratory animals will result in alimentary and [[Urinary Bladder - Anatomy & Physiology|bladder]] tumours.
*However, in many naturally-occurring cases of upper alimentary carcinoma in cattle there are coexisting viral papillomata, some of which show malignant change.
*The relationship between the ingestion of bracken and the presence of virus in the aetiology of the malignancies is currently the subject of intensive investigations.
*It may be that both are involved in the carcinogenesis.

=====Macroscopically=====
*These upper alimentary squamous carcinomas are most often seen as:
**large
**fungating
**often superficially-necrotic
**protruding into the lumen of the [[Alimentary - Anatomy & Physiology|alimentary tract]];
*There is often a marked scirrhous reaction.
*The tumours are locally aggressive and may permeate local lymphatics and metastasise to local lymph nodes.

=====Microscopically=====
The tumour consists of cords or groups of squamous cells, which may form keratin.
Individual or multiple papillomata may be found in association with the carcinomata.
*The presence of the tumours interferes with normal alimentary function
**there may be difficulty in chewing and [[Deglutition|swallowing]] or in cudding and [[Eructation - Anatomy & Physiology|eructation]].[[Category:Oesophagus_-_Pathology]][[Category:Cattle]]

@@ Line 24: / Line 24: @@
 Individual or multiple papillomata may be found in association with the carcinomata.
 *The presence of the tumours interferes with normal alimentary function
-**there may be difficulty in chewing and [[Deglutition|swallowing]] or in cudding and [[Eructation - Anatomy & Physiology|eructation]].
+**there may be difficulty in chewing and [[Deglutition|swallowing]] or in cudding and [[Eructation|eructation]].
 [[Category:Oesophagus_-_Pathology]][[Category:Alimentary Diseases - Cattle]]
 [[Category:Neoplasia]][[Category:To Do - Alimentary]][[Category:To Do - Medium]]

← Older revision		Revision as of 12:17, 4 May 2011
Line 28:		Line 28:

	[[Category:Oesophagus_-_Pathology]][[Category:Alimentary Diseases - Cattle]]		[[Category:Oesophagus_-_Pathology]][[Category:Alimentary Diseases - Cattle]]
−	[[Category:Neoplasia]][[Category:To Do - ~~Clinical~~]]	+	[[Category:Neoplasia]][[Category:To Do - Alimentary]][[Category:To Do - Medium]]

@@ Line 3: / Line 3: @@
 *This tumour is seen as part of a more general syndrome of upper alimentary tract neoplasia in adult cattle grazing rough pasture on which the '''bracken fern''' (Pteridium aquilinum) is present.
 *The syndrome is seen in various part of the world including the Western Highlands of Scotland, Brazil and Kenya.
-*In affected animals, squamous carcinomas may be present in the [[Oropharynx - Anatomy & Physiology|oropharynx]], [[Oesophagus - Anatomy & Physiology|oesophagus]] and [[Rumen - Anatomy & Physiology|rumen]] and there may also be [[Intestinal Adenocarcinoma|intestinal adenocarcinomas]] and bladder tumours, or the condition known as [[Enzootic Bovine Haematuria|enzootic bovine haematuria]].
+*In affected animals, squamous carcinomas may be present in the [[Oropharynx - Anatomy & Physiology|oropharynx]], [[Oesophagus - Anatomy & Physiology|oesophagus]] and [[Rumen - Anatomy & Physiology|rumen]] and there may also be [[Intestinal Adenocarcinoma|intestinal adenocarcinomas]] and bladder tumours, or the condition known as enzootic bovine haematuria.
 =====Pathogenesis=====

@@ Line 16: / Line 16: @@
 **fungating
 **often superficially-necrotic
-**protruding into the lumen of the [[Alimentary - Anatomy & Physiology|alimentary tract]];
+**protruding into the lumen of the [[Alimentary System Overview - Anatomy & Physiology|alimentary tract]];
 *There is often a marked scirrhous reaction.
 *The tumours are locally aggressive and may permeate local lymphatics and metastasise to local lymph nodes.

Upper Alimentary Tract Carcinoma Complex - Revision history

Bara: Text replace - "[[Eructation - Anatomy & Physiology" to "[[Eructation"

Bara at 12:17, 4 May 2011

Bara at 13:20, 17 January 2011

Bara at 13:20, 17 January 2011

Bara: Text replace - "[[The Rumen - Anatomy & Physiology|" to "[[Rumen - Anatomy & Physiology|"

Bara: Text replace - "[[Oral Cavity - Oropharynx - Anatomy & Physiology|" to "[[Oropharynx - Anatomy & Physiology|"

Bara: Text replace - "[[Alimentary - Anatomy & Physiology|" to "[[Alimentary System Overview - Anatomy & Physiology|"

Bara at 11:57, 1 July 2010

Bara at 22:27, 28 June 2010

Bara: Created page with '=====Aetiology===== *The most important oesophageal neoplasm is squamous cell carcinoma in the cow. *This tumou…'

Bara: Created page with '=====Aetiology===== The most important oesophageal neoplasm is squamous cell carcinoma in the cow. This tumou…'