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Herpesviridae (view source)

Revision as of 14:01, 17 August 2007

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==Introduction==

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===Feline herpesvirus -1===

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*Feline viral rhinotracheitis in [[Nasal cavity - inflammatory#Rhinitis|rhinitis]]

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**One of the causes of Feline viral rhinotracheitis

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***Viruses and bacteria are involved in the complex. The most frequent aetiologic agent is FHV-1, and less frequently feline calicivirus and/or ''Chlamydophia psittaci'' (NB: previously called Chlamydia psittaci var felis)

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***All three agents infect URT respiratory epithelium, although FHV-1 has the highest affinity for this epithelium

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***Feline calicivirus more frequently infects the oral mucosa -> ulcerative stomatitis

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***C.psittaci more frequently infects the conjunctival epithelium -> chronic conjunctivitis

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***Infection of the respiratory epithelium by FHV-1 results in a typical neutrophilic rhinitis with intraepitheial intranuclear eosinophilic inclusion bodies, with expected clinical signs

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***Resolution of clinical signs usually occurs by 7-14 days.

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***FHV-1 remains latent in the trigeminal ganglion, and can reactivate at times of stress. Can infect the cornea -> ulcerative keratitis.

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***Occasional mortality in kitten or immunocompromised animals usually associated with secondary bacterial infection.

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===Bovine herpesvirus -1===

* Bovine herpesvirus - 1 (Infectious bovine rhinotracheitis virus) contributes to [[Intestines - Catarrhal Enteritis#Undifferentiated Neonatal Calf Diarrhoea|undifferentiated neonatal calf diarrhoea]], a mixed viral enteritis in calves; and [[Nasal cavity - inflammatory#Rhinitis|rhinitis]]

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~~===Bovine herpesvirus -1===~~

*Causes '''Infectious bovine rhinotracheitis (IBR)'''

*Highly infectious URT disease of cattle

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