Changes

* Occurs as part of the response to corticosteroids;.

** Thought to be associated with the depressive effect of corticosteroids on lymphocytes.

Eosinopaenia refers to a reduction in the normal number of circulating blood [[Eosinophil|eosinophils]].  It ocurs most commonly as part of a stress leucocgram and in other situations that result in an increase in the circulating concentration of glucocorticoids:

*** Secretions of these lymphocytes are thought to stimulate eosinophil production.

*'''Stress leucogram''', with which [[Neutrophilia|neutrophilia]], [[Monocytosis|monocytosis]] and [[Lymphopenia|lymphopaenia]] would also be expected. 

[[Category:Blood Cell Changes]][[Category:To Do - Blood]]

*'''Hyperadrenocorticism''' (Cushing's disease) results in a similar pattern due to an increase in endogenous glucocorticoids.

*'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations.

 

Corticosteroids are thought to exert a depressive effect on lymphocytes that usually stimulate eosinophil production.

 

[[Category:Blood Cell Changes]][[Category:To Do - James]]