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Bullous Pemphigoid
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Revision as of 16:51, 22 February 2011
482 bytes added
,
16:51, 22 February 2011
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'''Pathogenesis:''' [[Type II Hypersensitivity|Type II hypersensitivity]]?
−
'''Pathogenesis
:
'''
[[
Type II Hypersensitivity
|
Type II hypersensitivity
]]
+
*Dogs and horses
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*Involves oral cavity, mucocutaneous junctions, groin and axilla
+
*Subepidermal vesicles and bullae
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*Antibodies bound to basement membrane
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*Grossly
:
+
**Similar to
[[
Pemphigus
|
Pemphigus vulgaris
]]
+
*Microscopically:
+
**Bullae containing fibrin, [[Neutrophils|neutrophils]] or [[Eosinophils|eosinophils]]
+
**Basement membrane forms floor of bullae and roof is lined with basal cells
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*Bullae may rupture -> ulcers
+
+
[[Category:Integumentary System - Autoimmune Reactions]]
[[Category:Antibody Mediated Autoimmune Diseases]]
[[Category:Antibody Mediated Autoimmune Diseases]]
[[Category:To Do - Blood]][[Category:To Do - Clinical]]
[[Category:To Do - Blood]][[Category:To Do - Clinical]]
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