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*Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]].
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== Introduction<br> ==
*Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively.
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*May be primary autoimmune or part of another autoimmune condition.
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*Causes of xerostomia:
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**Dysautonomia
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**Infectious sialadenitis
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**Neoplasia
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**Salivary amyloidosis
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**Head and neck radiation
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**Drugs
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**AutoI disease.
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'''Tagging-PG'''
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This is a rare syndrome is a complex of&nbsp; Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.<br>
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[[Category:Salivary Glands - Pathology]]
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Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease. <br>
[[Category:To_Do_-_Clinical]]
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<br>
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== Clinical Signs<br> ==
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Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, stomatitis, gingivitis and glossitis are all possible clinical signs.<br>
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<br>
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== Diagnosis<br> ==
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Diagnosis by elimination of all other causes of these clinical signs.<br>
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<br>
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== Treatment<br> ==
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None.<br>
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Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.<br>
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<br>
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== Prognosis<br> ==
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Guarded to Poor<br>
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<br>
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== References<br> ==
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Merck &amp; Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial<br>Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier. <br>Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams &amp; Wilkins. <br><br>
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'''<br>'''
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[[Category:Salivary_Glands_-_Pathology]] [[Category:To_Do_-_Review]]
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