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==Treatment==
 
==Treatment==
 
===Ancillary medication===
 
===Ancillary medication===
'''NSAIDs''': DMSO IV as 10% solution, thought to reduce CSF pressure and improve clinical status.  Recommended for severe cases of EPM or to avoid worsening inflammation that may be induced by parasite kill(Furr).  Caution: DMSO may cause intravascular haemolysis(Pasq).
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*'''NSAIDs''': DMSO IV as 10% solution, thought to reduce CSF pressure and improve clinical status.  Recommended for severe cases of EPM or to avoid worsening inflammation that may be induced by parasite kill(Furr).  Caution: DMSO may cause intravascular haemolysis(Pasq).
 
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*'''Corticosteroids''': a short course of dexamethasone may be beneficial whilst waiting for antiprotozoals to take effect.  However, use is controversial because cell-mediated immunity is required to control parasites(Pasq) and stress is a proposed risk factor for EPM.(Furr)
'''Corticosteroids''': a short course of dexamethasone may be beneficial whilst waiting for antiprotozoals to take effect.  However, use is controversial because cell-mediated immunity is required to control parasites(Pasq) and stress is a proposed risk factor for EPM.(Furr)
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*'''Immunomodulators''': '''Levamisole''' influences T-cell mediated immunity and enhances phagocytosis.  '''Parapox ovis virus (PPOV)''' immunomodulator (Zylexis, Pfizer Animal Health, Kalamazoo, Mich).  This vaccine has been shown to upregulate the secretion of cytokines including IFN-γ in several species (110 in Furr).  IFN-γ is thought to be essential for the clearance of S neurona, thus PPOV may be useful in EPM.(Furr)
 
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*'''Multiple vitamin B supplement'''.(Pasq)
'''Immunomodulators''':
  −
*Levamisole influences T-cell mediated immunity and enhances phagocytosis
  −
*Parapox ovis virus (PPOV) immunomodulator (Zylexis, Pfizer Animal Health, Kalamazoo, Mich).  This vaccine has been shown to upregulate the secretion of cytokines including IFN-γ in several species (110 in Furr).  IFN-γ is thought to be essential for the clearance of S neurona, thus PPOV may be useful in EPM.(Furr)
  −
 
  −
'''Multiple vitamin B supplement'''.(Pasq)
      
===Supportive management===
 
===Supportive management===
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