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Porcine Parvovirus

Revision as of 21:55, 30 October 2008 by Bepocock (talk | contribs) (New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Parvoviridae |subtext1=PARVOVIRUSES |pagetype =Bugs }} <br> ====Antigenicity==== *Single serotype ====Hosts==== ...)

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VIRUSES
PARVOVIRUSES



Antigenicity

  • Single serotype

Hosts

  • Pigs

Pathogenesis

  • Principal viral cause of SMEDI syndrome: Stillbirths, Mummification, Embryonic Deaths, and Infertility
  • Replicates in alimentary epithelium followed by viremia
  • Often no clinical signs in breeding and growing stock
  • Transplacental infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers

Epidemiology

  • About 50% of UK pigs are antibody-positive
  • Transfer is orofecal or via fomites
  • Outbreaks occur as herd is developing immunity
  • Congenitally infected piglets act as herd reservoir

Diagnosis

  • Immunostaining of fetal tissues
  • Virus isolation in cell culture
  • HA on feces
  • Rising antibody titres in paired serum sample by HAI

Control

  • Inactivated vaccine (UK) or live attenuated (USA)
  • Infected piglets should be culled
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