Intermediate Mesoderm Development - Anatomy & Physiology

BACK TO DEVELOPMENTAL BIOLOGY

Introduction

The intermediate mesoderm exists as a strip of tissue between the lateral plate mesoderm and somites. It gives rise to the urinary system and some parts of the reproductive system. Kidney development includes three forms:

Pronephros

Mesonephros

Metanephros

Mammals develop all three, and continue to use the metanephros in adult life. More primitive animals have only the first one or two.

Pronephros

• The earliest kidney. Develops in the anterior of the animal (adjacent to somites 7 - 10). Eliminated in later development.

1. At intervals along the intermediate mesoderm, dorsal evaginations occur.
2. Evaginations extend caudally and eventually fuse with more caudal evaginations.
   • The caudal - most evagination fuses with the cloaca.
3. Forms a continuous excretory tube to the cloaca.
4. Capillaries develop at the medial aspect of the intermediate mesoderm so that waste can diffuse from the blood to the excretory channel.
5. Connections between the intermediate mesoderm and somites as well between the intermediate mesoderm and lateral plate mesoderm break down.