Difference between revisions of "Bovine Parainfluenza - 3"
Jump to navigation
Jump to search
(New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Paramyxoviridae |subtext1=PARAMYXOVIRIDAE |pagetype =Bugs }} <br> ====Pathogenesis==== *Virulence varies with is...) |
|||
| Line 15: | Line 15: | ||
*Cessation of [[Respiratory System General Introduction - Pathology#Mucociliary escalator|ciliary clearance]] and epithelial necrosis predisposes to secondary bacterial infections -> cough | *Cessation of [[Respiratory System General Introduction - Pathology#Mucociliary escalator|ciliary clearance]] and epithelial necrosis predisposes to secondary bacterial infections -> cough | ||
*May cause [[Respiratory Viral Infections - Pathology#Parainfluenza- 3|rhinitis]] of cattle | *May cause [[Respiratory Viral Infections - Pathology#Parainfluenza- 3|rhinitis]] of cattle | ||
| − | |||
| − | |||
====Diagnosis==== | ====Diagnosis==== | ||
*Diseased lung tissue from dead animals or centrifuged cells from lung lavage | *Diseased lung tissue from dead animals or centrifuged cells from lung lavage | ||
| Line 28: | Line 26: | ||
**Temperature sensitive mutant that replicates at 34<sup>o</sup>C but not at 37<sup>o</sup>C | **Temperature sensitive mutant that replicates at 34<sup>o</sup>C but not at 37<sup>o</sup>C | ||
**Re-infection is common | **Re-infection is common | ||
| + | ====Secondary Concerns==== | ||
| + | *With other agents causes [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|calf pneumonia ]] | ||
| + | *Associated with poor management: | ||
| + | **Overcrowding | ||
| + | **Poor ventilation | ||
| + | **High humidity | ||
| + | **Deprivation of colostrum | ||
| + | **Stress caused by transport or mixing of stock | ||
Revision as of 18:48, 13 October 2008
 |
This article is still under construction. |
|
Pathogenesis
- Virulence varies with isolates
- Cessation of ciliary clearance and epithelial necrosis predisposes to secondary bacterial infections -> cough
- May cause rhinitis of cattle
Diagnosis
- Diseased lung tissue from dead animals or centrifuged cells from lung lavage
- Virus is too fragile for cell culture isolation (often inactivated in transport)
- Antigen detection by immunocytochemistry for intracytoplasmic viral inclusions containing labelled viral protein
- Serology: 4-fold rise in ELISA antibody in paired serum samples from several animals
Control
- Improve managemental factors
- All-in, all-out systems
- Some vaccination
- Temperature sensitive mutant that replicates at 34oC but not at 37oC
- Re-infection is common
Secondary Concerns
- With other agents causes calf pneumonia
- Associated with poor management:
- Overcrowding
- Poor ventilation
- High humidity
- Deprivation of colostrum
- Stress caused by transport or mixing of stock