- The mucosa eroded to produce lesions of darkish-red submucosa covered in dry, crumbly fibrin.
- Is usually caused by severe damage due to secondary bacterial infection following an earlier milder insult.
- Tends to be more severe in the lower small intestine and upper large intestine.
- Many severe infections tend to get worse further down the gut.
- In the lower aprt of the bowel, where the inflammation is more severe, disease is more anaerobic.
- Lesions are caused by anaerobic organisms- convert mild diseases into more serious disease.