Changes

==Why is it Important?==

==Why is it Important?==

The main function of chloride is in '''maintaining acid-base balance''' and '''contributing to the osmotic pressure found in extracellular fluids'''.

The main function of chloride is in '''maintaining [[Essential Ion and Compound Balance and Homeostasis - Anatomy & Physiology|acid base balance]]''' and '''contributing to the osmotic pressure found in extracellular fluids'''.

==Roles in the Body==

==Roles in the Body==

====Recognised Syndromes Related to Chloride Deficiency====

====Recognised Syndromes Related to Chloride Deficiency====

Signs of chloride deficiency were observed in puppies fed a milk substitute diet containing 0.021% chloride on a dry matter (DM) basis. After two weeks puppies developed low plasma chloride and [[Potassium - Nutrition|potassium]] and a metabolic alkalosis. General weakness, ataxia and stunted growth were noted. In comparison, puppies fed a diet with a chloride content of about 0.3% DM showed normal growth and no abnormalities<ref>Felder, C, Robillard, J, Roy III, S, Jose, P (1987). “Severe chloride deficiency in the neonate: The canine puppy as an animal model”. Pediat. Res. 21:497-501.</ref>.

Signs of chloride deficiency were observed in puppies fed a milk substitute diet containing 0.021% chloride on a [[Nutrition Glossary#Dry Matter Basis|dry matter (DM) basis]]. After two weeks puppies developed low plasma chloride and [[Potassium - Nutrition|potassium]] and a metabolic alkalosis. General weakness, ataxia and stunted growth were noted. In comparison, puppies fed a diet with a chloride content of about 0.3% DM showed normal growth and no abnormalities<ref>Felder, C, Robillard, J, Roy III, S, Jose, P (1987). “Severe chloride deficiency in the neonate: The canine puppy as an animal model”. Pediat. Res. 21:497-501.</ref>.

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===Cat:===   

==References==

==References==

<references/>

<references/>

[[Category:Minerals in Nutrition]]

[[Category:Minerals in Nutrition]]