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Caused by [[Actinobacillus pleuropneumoniae]]
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#redirect[[Actinobacillus pleuropneumoniae]]
 
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*Clinical signs and epidemiology:
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**Acute disease in susceptible herds with high morbidity and mortality (up to 50%)
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**In acute outbreaks, pigs may be dyspnoeic, pyrexic or anorexic
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**Blood-stained froth surrounding nose and mouth
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**Cyanosis
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**Pregnant sows abort
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**Causes [[Respiratory Bacterial Infections - Pathology#Actinobacillus pleuropneumoniae|pneumonia]] in pigs
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**Carrier herds have some immunity, protecting from acute disease, where lesions are often subclinical, and deaths sporadic
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**Lung scarring and pleural adhesions in many recovered animals
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**Solid immunity develops in recovered animals to all serotypes
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**The disease is spread between herds by carrier pigs
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*Diagnosis:
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**Haemorrhagic consolidation close to the main bronchi and fibrinous pleuritis may be suggestive
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**Specimens are cultured on chocolate agar and blood agar in 5-10% carbon dioxide for 2-3 days
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**Small colonies surrounded by clear haemolysis
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**No growth on MacConkey agar
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**Positive CAMP reaction with ''[[Staphylococcus aureus]]''
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**Most strains are NAD-dependent (grow on Heated Blood agar)
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**Immunofluorescent- or PCR-based techniques
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**The bacteria on the [[Tonsils - Anatomy & Physiology#Palatine|palatine tonsil]] may remain undetected by serological tests and swabbing, and can therefore cause an outbreak in naive pigs
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*Treatment:
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**Antibiotics depending on the strain of bacteria
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**Prophylactic antibiotics for in-contact pigs
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*Control:
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**Killed and polyvalent bacterin vaccines as well as a subunit vaccine are available 
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**Improve ventilation, avoid chilling and overcrowding
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[[Category:Pig]][[Category:To_Do_-_Clinical]]
 
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