Ehrlichia canis

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Canine monocytic ehrlichiosis

  • Generalised disease of dogs in tropical and subtropical regions
  • Caused by Ehrlichia canis
  • The brown tick, Rhipicephalus sanguineus, is the main vector
  • Dogs may carry the organism for 2 years after resolution of clinical signs
  • Clinical signs
    • Incubation period of 3 weeks
    • Acute, subclinical or chronic phases
    • Acute phase: fever, thrombocytopenia, leukopenia and anaemia
    • Subclinical phase: low blood cell numbers but minimal clinical signs; can progress to a severe disease, tropical canine pancytopenia
    • Chronic phase: bone marrow depression, haemorrhages, neurological disease, peripheral oedema, emaciation and hypotensive shock
  • Diagnosis
    • E. canis morulae present in mononuclear cells in Giemsa-stained blood smears
    • Rising antibody titre detected by indirect immunofluorescence
    • Culture in canine macrophages
  • Treatment and control
    • Doxycycline for 10 days
    • Fluid therapy or blood transfusion
    • Prophylactic tetracyclines



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Update on canine ehrlichiosis/anaplasmosis and rocky mountain spotted fever. Birkenheuer, A.; The North American Veterinary Conference, Gainesville, USA, Small animal and exotics. Proceedings of the North American Veterinary Conference, Orlando, Florida, USA, 17-21 January, 2009, 2009, pp 639-640

Tick-borne disease testing: canine erhlichiosis and anaplasmosis. Alleman, R.; The North American Veterinary Conference, Gainesville, USA, Small animal and exotics. Proceedings of the North American Veterinary Conference, Orlando, Florida, USA, 17-21 January, 2009, 2009, pp 629-631

Recent concepts in diagnosis of canine ehrlichiosis. Bindu Lakshmanan; Lalitha John; Intas Pharmaceuticals Ltd, Ahmedabad, India, Intas Polivet, 2007, 8, 1, pp 124-127, 30 ref.

Canine ehrlichiosis - a review. Kafil Hussain; Soodan, J. S.; Neelesh Sharma; Upadhyay, S. R.; North-East Veterinarian, Guwahati, India, North-East Veterinarian, 2006, 6, 2, pp 18-20, 13 ref.

Tick-borne disease testing: canine erhlichiosis and anaplasmosis. Alleman, R.; The North American Veterinary Conference, Gainesville, USA, Small animal and exotics. Proceedings of the North American Veterinary Conference, Orlando, Florida, USA, 17-21 January, 2009, 2009, pp 629-631