Eumycotic Mycetoma

• Pseudoallescheria boydii, Curvularia geniculata, Cochliobolus spicifer, Helminthosporium spp.

• Lives in soil

• Enters the body via wounds

• Granulomatous abscesses

• Microcolonies can be seen grossly in exudate or lesions
  • Grains or granules
  • Brown or black embedded in granulation tissue
  • Small, irregularly shaped

• Infrequent infections of dogs, cats, cattle and horses

• Usually affect the extremities
  • Can infect the nasal mucosa
    • E.g. Bovine nasal granuloma
  • Can also infect the peritoneum and skin

• Microscopically:
  • Grains of maduromycosis with wide mycelia (compared to actinomycotic granules)
  • Chlamydospores present

• Grows on Sabauraud's Dextrose agar
  • Slow
  • Takes 2-3 weeks

• Treatment includes Ketoconazole, 5-fluorocytosine and amphotericin B