Difference between revisions of "Fusobacterium necrophorum"
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''F.necrophorum'' is a pathogenic, anaerobic, non-spore-forming Gram-negative bacteria; it is a normal inhabitant of the mammalian gut and cannot invade normal tissue. | ''F.necrophorum'' is a pathogenic, anaerobic, non-spore-forming Gram-negative bacteria; it is a normal inhabitant of the mammalian gut and cannot invade normal tissue. | ||
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Antibody levels to ''F.necrophorum'' rise with age, suggesting that these are not protective. | Antibody levels to ''F.necrophorum'' rise with age, suggesting that these are not protective. | ||
| − | ''F.necrophorum'' is associated with bucket feeding, where buckets are contaminated with faeces. Bacteria enter through abrasions in the mucosa of the pharynx and larynx and cause fever, depression, anorexia, salivation, respiratory distress and halitosis. Aspiration of necrotic material into lungs may cause fatal [[Lungs Inflammatory - Pathology#Infectious causes of | + | ''F.necrophorum'' is associated with bucket feeding, where buckets are contaminated with faeces. Bacteria enter through abrasions in the mucosa of the pharynx and larynx and cause fever, depression, anorexia, salivation, respiratory distress and halitosis. Aspiration of necrotic material into lungs may cause fatal [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|bronchopneumonia]]. |
''F.necrophorum'' causes a number of necrotic wound infections often in association with facultative anaerobes. | ''F.necrophorum'' causes a number of necrotic wound infections often in association with facultative anaerobes. | ||
It causes; | It causes; | ||
| − | '''Cows''': [[Calf Diphtheria| | + | '''Cows''': [[Calf Diphtheria|calf diphtheria]] or necrotic laryngitis in cattle and necrobacillosis of the mouth and pharynx of young calves. Also, [bovine liver abscesses]] and localised necrosis and scab formation of the teat orifice and sphincter of dairy cows. |
| − | '''Pigs''': [[ | + | '''Pigs''': [[necrotic rhinitis]] in pigs. |
| − | '''Sheep''': | + | '''Sheep''': interdigital dermatitis, ([[Bacterial skin infections - Pathology#Bacterial pododermatitis|pododermatitis]]) in sheep in association with ''D. nodosus'' and [[Arcanobacter pyogenes|''Arcanobacter pyogenes'']], predisposing to [[Contagious Footrot|footrot]]. It also causes [[Laryngeal Chondritis|laryngeal chondritis]] in sheep and mixed infections in heel abscesses. |
| − | ''F.necrophorum'' is also involved in; [[Thrush - Hoof| | + | ''F.necrophorum'' is also involved in; [[Thrush - Hoof|hoof thrush]]; Mixed infections in [[Pleural Cavity & Membranes Inflammatory - Pathology#Pyothorax (Thoracic empyema)|pyothorax]]; mixed infections in aspiration pneumonia and in bovine traumatic reticuloperitonitis and pericarditis; [[Bacterial skin infections - Pathology#Subcutaneous abscesses|subcutaneous abscesses]] due to cat bites; [[Nasal Cavity Inflammatory - Pathology#Chronic rhinitis|chronic fibronecrotic rhinitis]]; [[Bones Inflammatory - Pathology#Osteitis|osteitis]]; [[Contagious Footrot|contagious footrot]]; [[Necrobacillosis|necrobacillosis]] and [[Laryngeal Chondritis|laryngeal chondritis]]. |
==Treatment== | ==Treatment== | ||
Treatment against ''F.necrophorum'' includes potentiated sulphonamides or tetracyclines. | Treatment against ''F.necrophorum'' includes potentiated sulphonamides or tetracyclines. | ||
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| + | ==Literature Search== | ||
| + | [[File:CABI logo.jpg|left|90px]] | ||
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| + | Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation). | ||
| + | <br><br><br> | ||
| + | [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Fusobacterium+necrophorum%22&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&x=57&y=9&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all ''Fusobacterium necrophorum'' publications] | ||
[[Category:Gram Negative Anaerobic Bacteria]] | [[Category:Gram Negative Anaerobic Bacteria]] | ||
[[Category:To_Do_-_AimeeHicks]][[Category:Expert_Review]] | [[Category:To_Do_-_AimeeHicks]][[Category:Expert_Review]] | ||
Revision as of 10:13, 30 September 2010
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This article has been peer reviewed but is awaiting expert review. If you would like to help with this, please see more information about expert reviewing. |
| Fusobacterium necrophorum | |
|---|---|
| Phylum | Fusobacteria |
| Class | Fusobacteria |
| Order | Fusobacteriales |
| Family | Fusobacteriaceae |
| Genus | Fusobacterium |
| Species | F.necrophorum |
F.necrophorum is a pathogenic, anaerobic, non-spore-forming Gram-negative bacteria; it is a normal inhabitant of the mammalian gut and cannot invade normal tissue.
Characteristics
F.necrophorum is pleimorphic and is either long and filamentous or a short cocci. It is fermentative and haemolytic on blood agar. It produces grey, round and shiny colonies. There are three biotypes, biotype A has the greatest haemolytic activity and virulence.
Pathogenesis and pathogenicity
F.necrophorum is a primary pathogen in various diseases of farm animals. It forms mixed bacterial infections and can be secondary to IBR. Extracellular haemolysin contributes to infection and heat-stable leucocidin is correlated with biotype and virulence. Cytoplasmic toxin is haemolytic and LPS endotoxin causes host damage. Antibody levels to F.necrophorum rise with age, suggesting that these are not protective.
F.necrophorum is associated with bucket feeding, where buckets are contaminated with faeces. Bacteria enter through abrasions in the mucosa of the pharynx and larynx and cause fever, depression, anorexia, salivation, respiratory distress and halitosis. Aspiration of necrotic material into lungs may cause fatal bronchopneumonia.
F.necrophorum causes a number of necrotic wound infections often in association with facultative anaerobes. It causes;
Cows: calf diphtheria or necrotic laryngitis in cattle and necrobacillosis of the mouth and pharynx of young calves. Also, [bovine liver abscesses]] and localised necrosis and scab formation of the teat orifice and sphincter of dairy cows.
Pigs: necrotic rhinitis in pigs.
Sheep: interdigital dermatitis, (pododermatitis) in sheep in association with D. nodosus and Arcanobacter pyogenes, predisposing to footrot. It also causes laryngeal chondritis in sheep and mixed infections in heel abscesses.
F.necrophorum is also involved in; hoof thrush; Mixed infections in pyothorax; mixed infections in aspiration pneumonia and in bovine traumatic reticuloperitonitis and pericarditis; subcutaneous abscesses due to cat bites; chronic fibronecrotic rhinitis; osteitis; contagious footrot; necrobacillosis and laryngeal chondritis.
Treatment
Treatment against F.necrophorum includes potentiated sulphonamides or tetracyclines.
Literature Search
Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
Fusobacterium necrophorum publications