Difference between revisions of "Gastric Neoplasia - Dog and Cat"

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More common compared with oesophageal neoplasia but still uncommon accounting for less than 1% of all malignancies. Malignant tumours include:
 
More common compared with oesophageal neoplasia but still uncommon accounting for less than 1% of all malignancies. Malignant tumours include:
* [[Stomach and Abomasum Proliferative - Pathology #Adenocarcinoma|Adenocarcinoma]]
+
* [[Stomach and Abomasum Proliferative - Pathology #Adenocarcinoma|Adenocarcinoma]] - 70-80% of cancers of the somach in dogs
 
* [[Stomach and Abomasum Proliferative - Pathology #Squamous cell carcinoma|Squamous Cell Carcinoma]]
 
* [[Stomach and Abomasum Proliferative - Pathology #Squamous cell carcinoma|Squamous Cell Carcinoma]]
* [[Stomach and Abomasum Proliferative - Pathology #Lymphoma|Lymphoma]]
+
* [[Stomach and Abomasum Proliferative - Pathology #Lymphoma|Lymphoma]] - the most common gastric neoplasm in the cat
 
* Fribrosarcoma  
 
* Fribrosarcoma  
 
* Plasmacytoma
 
* Plasmacytoma
 
* Leiomyosarcoma
 
* Leiomyosarcoma
 +
* Mast cell
 
Benign tumours include:
 
Benign tumours include:
 
* Polyps
 
* Polyps
 
* [[Stomach and Abomasum Proliferative - Pathology #Leiomyoma|Leiomyoma]]
 
* [[Stomach and Abomasum Proliferative - Pathology #Leiomyoma|Leiomyoma]]
 +
  
 
==Signalment==
 
==Signalment==
* Male dogs are more commonly affected than female:
+
* Male dogs are more commonly affected than female: e.g male:female ratio in those with carcinoma 2.5:1
* Mean age of dogs with carinoma 8 years
+
* Mean age of dogs with carinoma - 8 years
* Cats with carcinoma over 10 years
+
* Cats with carcinoma - usually over 10 years
* Mean age of dogs with benign tumour 15 years
+
* Mean age of dogs with benign tumour - 15 years
 +
 
  
 
==Description==  
 
==Description==  
 
Aetiology largely idiopathic though long term ingestion of dietary carcinogens may have some responsibility. Long term administration of nitrosamines may cause carcinomas in dogs. In humans, the bacterium ''Helicobacter pylori'' can induce gastric carcinoma and lymphoma. Its role in gastric tumours in dogs and cats has not yet been fully established though it can cause gastritis and ulceration. Belgian Shepher dogs may have a genetic predisposition to gastric carcinoma. Cats with gastric lymphoma are not usually FeLV positive.
 
Aetiology largely idiopathic though long term ingestion of dietary carcinogens may have some responsibility. Long term administration of nitrosamines may cause carcinomas in dogs. In humans, the bacterium ''Helicobacter pylori'' can induce gastric carcinoma and lymphoma. Its role in gastric tumours in dogs and cats has not yet been fully established though it can cause gastritis and ulceration. Belgian Shepher dogs may have a genetic predisposition to gastric carcinoma. Cats with gastric lymphoma are not usually FeLV positive.
 +
  
 
==Diagnosis== (based on typical history, clinical signs, physical exam findings, imaging/laboratory results)
 
==Diagnosis== (based on typical history, clinical signs, physical exam findings, imaging/laboratory results)
 +
===History and Clinical Signs===
 +
* Chronic vomiting - blood tinged/'coffee grounds' appearance
  
 
==Treatment==
 
==Treatment==
 +
  
 
==Prognosis==
 
==Prognosis==
 +
Adenocarcinoma frequently metastasises to the regional lympho nodes, also the liver and lungs.
 +
  
 
==References==
 
==References==

Revision as of 09:44, 11 August 2009



More common compared with oesophageal neoplasia but still uncommon accounting for less than 1% of all malignancies. Malignant tumours include:

Benign tumours include:


Signalment

  • Male dogs are more commonly affected than female: e.g male:female ratio in those with carcinoma 2.5:1
  • Mean age of dogs with carinoma - 8 years
  • Cats with carcinoma - usually over 10 years
  • Mean age of dogs with benign tumour - 15 years


Description

Aetiology largely idiopathic though long term ingestion of dietary carcinogens may have some responsibility. Long term administration of nitrosamines may cause carcinomas in dogs. In humans, the bacterium Helicobacter pylori can induce gastric carcinoma and lymphoma. Its role in gastric tumours in dogs and cats has not yet been fully established though it can cause gastritis and ulceration. Belgian Shepher dogs may have a genetic predisposition to gastric carcinoma. Cats with gastric lymphoma are not usually FeLV positive.


==Diagnosis== (based on typical history, clinical signs, physical exam findings, imaging/laboratory results)

History and Clinical Signs

  • Chronic vomiting - blood tinged/'coffee grounds' appearance

Treatment

Prognosis

Adenocarcinoma frequently metastasises to the regional lympho nodes, also the liver and lungs.


References