Difference between revisions of "Gastritis, Haemorrhagic"

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[[Category:Stomach_and_Abomasum_-_Inflammatory_Pathology]][[Category:Gastric Diseases - Pig]][[Category:Sheep]]
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[[Category:Stomach_and_Abomasum_-_Inflammatory_Pathology]][[Category:Gastric Diseases - Pig]][[Category:Gastric Diseases - Sheep]]
[[Category:To_Do_-_Clinical]]
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[[Category:To_Do_-_Alimentary]][[Category:To Do - Medium]]

Latest revision as of 13:12, 10 May 2011

Clinical

  • Usually only seen post mortem.
  • Stomach full of thick tarry clots.
  • Occasionally will vomit blood in life.

Pathology

Haemorrhagic gastritis (Courtesy of BioMed Image Archive)

Gross

  • Wall of stomach is blacked and ulcerated.
    • Red, thickened, necrotic, haemorrhagic mucosa.

Histologically

  • Coagulative necrosis with fibrin, oedema, haemorrhage, and sometimes emphysema.
  • May extend deep into submucosa/muscle.

Pathogenesis

  • There are several causes of haemorrhagic gastritis
    1. Aspirin and non-steroidal anti inflammatory drug toxicity.
    2. Peracute / acute infections, e.g.
      • Swine Fever
      • Anthrax
      • Leptospirosis in dogs (Leptospira icterohaemorrhagiae).
    3. Clostridial disease
      • e.g. Braxy (Clostridium septicum)
        • Affects older lambs or yearlings producing sudden death.
        • Usually seen on sheep grazing on frosted grass so more common in colder areas.
        • Bacterial exotoxin causes acute abomasitis.
        • Pathology- At post mortem the stomach is grossly distended with partially clotted blood. The wall of the stomach is thickened,reddened and oedematous.
        • Diagnosed by isolation of organism from the stomach wall.
        • Is now usually vaccinated against (Heptovac 7 in 1 clostridial vaccine).
    4. Anticoagulant Rodenticide Toxicity.