Gluten-Sensitive Enteropathy

• Affects Irish setters
• Caused by a single major autosomal recessive gene
  • Note: most genetic diseases in dogs are autosomal recessive
    • Unlike humans- most are autosomal dominant.
• Histology
  • Partial villus atrophy in the jejunum.
  • Increased intestinal permeability.

Gluten-Sensitive Enteropathy Learning Resources
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