Granulation Tissue
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- Is completlely different to granulomatous inflammation, despite the similarity in name!
- Occurs on the surface of the skin where large areas of the epithelium have been lost.
- Makes up the lining of sinus tracts discharging from deeper lesions.
- Takes its name from the gross appearance of the small vessels which appear at the surface.
- Look like red granules.
- These vessels supply inflammatory cells, mainly neutrophils, to the infected surface.
- The most frequent example in domestic animals is the formation of excessive granulation tissue on the legs of horses with poorly healing wounds.
- "Proud flesh"
- Ulcers and open wounds may heal by granulation.