Difference between revisions of "Gut Endocrine Function - Anatomy & Physiology"
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|<font color=Purple>Cholecystokinin</font> | |<font color=Purple>Cholecystokinin</font> | ||
| − | |Duodenum | + | |[[Duodenum - Anatomy & Physiology|Duodenum]] |
| − | |Stimulates digestion of fat and protein by causing release of digestive enzymes and bile from the [[Pancreas - Anatomy & Physiology|pancreas]] and gall bladder. | + | |Stimulates digestion of fat and protein by causing release of digestive enzymes and bile from the [[Pancreas - Anatomy & Physiology|pancreas]] and [[Gall Baldder - Anatomy & Physiology|gall bladder]]. |
|- | |- | ||
|<font color=Purple>Gastrin</font> | |<font color=Purple>Gastrin</font> | ||
| − | |G-Cells in | + | |G-Cells in [[Forestomach - Anatomy & Physiology|stomach]] and [[Duodenum - Anatomy & Physiology|duodenum]] |
|Stimulates Parietal cells in the [[Forestomach - Anatomy & Physiology|stomach]] to secrete HCl and Chief cells to secrete pepsinogen. | |Stimulates Parietal cells in the [[Forestomach - Anatomy & Physiology|stomach]] to secrete HCl and Chief cells to secrete pepsinogen. | ||
|- | |- | ||
|<font color=Purple>Gastric Inhibitory Peptide</font> | |<font color=Purple>Gastric Inhibitory Peptide</font> | ||
| − | |Duodenum and Jejunum | + | |[[Duodenum - Anatomy & Physiology|Duodenum]]and [[Jejunum - Anatomy & Physiology|Jejunum]] |
|Inhibits gastric motility and HCl secretion in the [[Forestomach - Anatomy & Physiology|stomach]], induces insulin secretion. | |Inhibits gastric motility and HCl secretion in the [[Forestomach - Anatomy & Physiology|stomach]], induces insulin secretion. | ||
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|<font color=Purple>Secretin</font> | |<font color=Purple>Secretin</font> | ||
|Crypts of Leiberkuhn in the Duodenum | |Crypts of Leiberkuhn in the Duodenum | ||
| − | |Causes secretion of bicarbonate to buffer the pH of the chyme entering the small intestine. Also triggers insulin release. | + | |Causes secretion of bicarbonate to buffer the pH of the chyme entering the [[Small Intestine - Anatomy & Physiology|small intestine]]. Also triggers insulin release. |
|- | |- | ||
|<font color=Purple>Somatostatin </font> | |<font color=Purple>Somatostatin </font> | ||
| − | |Gastric glands of the stomach | + | |Gastric glands of the [[Forestomach - Anatomy & Physiology|stomach]] |
| − | |Inhibits release of gastrin and HCl from the [[Forestomach - Anatomy & Physiology|stomach]], inhibits secretin and cholecystokinin release from the duodenum and inhibits release of glucagon from the [[Pancreas - Anatomy & Physiology|pancreas]]. | + | |Inhibits release of gastrin and HCl from the [[Forestomach - Anatomy & Physiology|stomach]], inhibits secretin and cholecystokinin release from the [[Duodenum - Anatomy & Physiology|duodenum]] and inhibits release of glucagon from the [[Pancreas - Anatomy & Physiology|pancreas]]. |
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Revision as of 08:59, 23 July 2008
Various regions of the Alimentary Tract secrete hormones which have various functions within the gastrointestinal tract itself, plus the liver, gall bladder and
pancreas.
Many of the hormones act in a paracrine fashion, exerting their effect on cells close to the secretion site without travelling in the bloodstream.
| Hormone | Site of Secretion within GIT | Action |
|---|---|---|
| Cholecystokinin | Duodenum | Stimulates digestion of fat and protein by causing release of digestive enzymes and bile from the pancreas and gall bladder. |
| Gastrin | G-Cells in stomach and duodenum | Stimulates Parietal cells in the stomach to secrete HCl and Chief cells to secrete pepsinogen. |
| Gastric Inhibitory Peptide | Duodenumand Jejunum | Inhibits gastric motility and HCl secretion in the stomach, induces insulin secretion. |
| Ghrelin | Stomach and Pancreas | Increases food intake (by stimulating hunger) at the level of the hypothalamus. |
| Secretin | Crypts of Leiberkuhn in the Duodenum | Causes secretion of bicarbonate to buffer the pH of the chyme entering the small intestine. Also triggers insulin release. |
| Somatostatin | Gastric glands of the stomach | Inhibits release of gastrin and HCl from the stomach, inhibits secretin and cholecystokinin release from the duodenum and inhibits release of glucagon from the pancreas. |