Difference between revisions of "Helicobacter"
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*''H. mustelae'' has been associated with chronic gastritis and gastric ulcers in ferrets | *''H. mustelae'' has been associated with chronic gastritis and gastric ulcers in ferrets | ||
*Significance in gastrointestinal diseases of domestic carnivores not known | *Significance in gastrointestinal diseases of domestic carnivores not known | ||
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| + | * Carried in the [[Forestomach - Anatomy & Physiology|stomach]] of a high proportion of people. | ||
| + | ** 60% in the elderly. | ||
| + | * Implicated in the development of peptic ulcers and gastritis in people. | ||
| + | * Strong epidemiological evidence for the involvement of ''H. pylori'' in human gastric neoplasia. | ||
| + | ** No evidence this is the case for animals. | ||
| + | * Several species demonstrated in dogs: ''H. felis'', ''H. bizzozeronii'', ''H. salomonis'' and ''H. bilis''. | ||
| + | ** Present in around 80% of clinically healthy pet dogs. | ||
| + | *** Up to 100% in dogs from animal shelters. | ||
| + | *Experimental infection of dogs has failed to show a consistent relationship between infection with ''Helicobacter'' and pathology. | ||
| + | ** Inflammation accompanies infection in some but not all infected dogs. | ||
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[[Category:Bacteria miscellaneous]][[Category:Rods]][[Category:Gram_negative_bacteria]] | [[Category:Bacteria miscellaneous]][[Category:Rods]][[Category:Gram_negative_bacteria]] | ||
| + | [[Category:Enteritis,_Bacterial]] | ||
Revision as of 11:19, 6 June 2010
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Overview
- Related to Campylobacter species and Arcobacter species
- A bacterial pathogen of the intestines
- Discovered in the stomach of humans in 1987
- H. felis, H. bizzozeronii, H. salomonis and H. bilis found in gastric mucosa and intestines of dogs and cats
Characteristics
- Helical, S-shaped or curved Gram negative rods
- Require enriched media; some grow on Skirrow agar
- Microaerophilic, non-saccharolytic
- Oxidase positive and catalase positive except for H. canis
- Helicobacters which colonise gastric mucosa are urease positive
Clinical infections
- Helicobacter pylori causes gastritis and duodenal and gastric ulcers in humans
- Association with gastric adenocarcinoma in humans
- H. mustelae has been associated with chronic gastritis and gastric ulcers in ferrets
- Significance in gastrointestinal diseases of domestic carnivores not known
- Carried in the stomach of a high proportion of people.
- 60% in the elderly.
- Implicated in the development of peptic ulcers and gastritis in people.
- Strong epidemiological evidence for the involvement of H. pylori in human gastric neoplasia.
- No evidence this is the case for animals.
- Several species demonstrated in dogs: H. felis, H. bizzozeronii, H. salomonis and H. bilis.
- Present in around 80% of clinically healthy pet dogs.
- Up to 100% in dogs from animal shelters.
- Present in around 80% of clinically healthy pet dogs.
- Experimental infection of dogs has failed to show a consistent relationship between infection with Helicobacter and pathology.
- Inflammation accompanies infection in some but not all infected dogs.