Helicobacter

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Overview

  • Related to Campylobacter species and Arcobacter species
  • A bacterial pathogen of the intestines
  • Discovered in the stomach of humans in 1987
  • H. felis, H. bizzozeronii, H. salomonis and H. bilis found in gastric mucosa and intestines of dogs and cats


Characteristics

  • Helical, S-shaped or curved Gram negative rods
  • Require enriched media; some grow on Skirrow agar
  • Microaerophilic, non-saccharolytic
  • Oxidase positive and catalase positive except for H. canis
  • Helicobacters which colonise gastric mucosa are urease positive


Clinical infections

  • Helicobacter pylori causes gastritis and duodenal and gastric ulcers in humans
  • Association with gastric adenocarcinoma in humans
  • H. mustelae has been associated with chronic gastritis and gastric ulcers in ferrets
  • Significance in gastrointestinal diseases of domestic carnivores not known